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Filtering by: Creator Hathaway, D. O. Remove constraint Creator: Hathaway, D. O. Academic Affiliation Chemistry Remove constraint Academic Affiliation: Chemistry File Format application/pdf Remove constraint File Format: application/pdf

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  • Studies toward the total synthesis of alkaloids : nagelamide A and D, agelastatin D, dragmacidin A-C, salacin and almazoles

    Creator:
    Tonsiengsom, Sorasaree
    Abstract:
    Studies toward the total syntheses of highly potent cytotoxic alkaloids including the bromopyrrole alkaloids and indole alkaloids were conducted and are described. Studies carried out in the course of this dissertation consist of five total syntheses of natural products that include bromopyrrole alkaloids nagelamide A, D and agelastatin D as...
    Resource Type:
    Dissertation
    Full Text:
    : R = Br agelastatin C 1.9 N NH NH N O O HO H H H H Br agelastatin D 1.10 A B C D HN N

  • Total synthesis of phorboxazole A

    Creator:
    Lee, Tae Hee
    Abstract:
    The total synthesis of a highly potent cytotoxic marine natural product, phorboxazole A, is described. Both a palladium(II)-mediated and a palladium(II)-catalyzed intramolecular alkoxycarbonylation were used as key steps for the preparation of the two cis-2,6-disubstituted tetrahydropyran rings (C22-C26 and C11-C15) of phorboxazole A. The synthesis used a convergent approach involving...
    Resource Type:
    Dissertation
    Full Text:
    , 3801. (n) Greer, P. B.; Donaldson, W. A. Tetrahedron 2002, 58, 6009. (o) White, J. D.; Kranemann, C. L

  • Studies towards the total synthesis of (-)-kendomycin

    Creator:
    Smits, Helmars
    Abstract:
    Studies towards the total synthesis of (−)-kendomycin (1), a bacterial metabolite with a unique molecular architecture and pronounced biological activity, are described. These studies resulted in the synthesis of advanced intermediate 208, containing all of the carbon atoms of 1. A Dötz annulation between alkyne 122 and novel chromium carbenoid...
    Resource Type:
    Dissertation
    Full Text:
    :_____________________________________________________ James D. White Studies towards the total synthesis of (−)-kendomycin (1), a bacterial

  • Design, characterization, and application of spectrometers for determination of low-level dissolved oxygen with small-volume sampling methodology

    Creator:
    Cakin, Defne
    Abstract:
    New analytical methods and instrumentation were developed for the determination of dissolved oxygen (DO) at low concentrations in water. The methods were based on monitoring the absorbance increase due to the oxidation of reduced indigo carmine (IC) by oxygen in the sample in different types of spectrometer cells. Spectrophotometer cells...
    Resource Type:
    Dissertation
    Full Text:
    : ___________________________________________ James D. Ingle, Jr. New analytical methods and instrumentation were developed for the

  • Studying fusion reactions for effect of PCN on heavy nucleus formation and for nuclear structure effects

    Creator:
    Naik, Radhika
    Abstract:
    The fusion reaction ²⁰⁸Pb (⁵⁰Ti, xn) ²⁵⁸⁻x Rf (x = 1-3) was studied to determine PCN (probability that the mononucleus system evolves to form a compound nucleus inside the fission saddle point) and to establish the value of Wsur (survival probability) for the given reaction experimentally. The fission excitation function...
    Resource Type:
    Dissertation
    Full Text:
    Walter D. Loveland The fusion reaction 208Pb (50Ti, xn) 258-xRf (x = 1-3) was studied to determine

  • Design, fabrication and application of a microfluidic nanofiltration module for separation and purification of macromolecules and nanoparticles

    Creator:
    Rundel, Jack T.
    Abstract:
    A microfluidic nanofiltration module has been designed, fabricated and applied to the continuous-flow, pressure-driven, post-synthetic purification of macromolecules and nanoparticles via diafiltration using a commercially available organic solvent resistant nanofiltration membrane, STARMEM 122. This module will readily interface with other microscale components within a "nanofactory" for the rapid synthesis, purification...
    Resource Type:
    Dissertation
    Full Text:
    -Aldrich) • PPh3 stabilized gold-eleven (Au11) o Crystalline standards (Lallie McKenzie, UO, Eugene, OR

  • Graphite intercalation compounds containing fluoroanions

    Creator:
    Katinonkul, Watcharee
    Abstract:
    New chemical synthesis strategies have been investigated for the preparation of acceptor-type graphite intercalation compounds (GIC's) with fluoroanions in order to obtain new materials and to develop a better understanding of the synthetic approaches and properties of the products. New GIC's containing borate chelate anion such as bis(oxalato)borate, CxB[OC(O)C(O)O]₂•δF, are...
    Resource Type:
    Dissertation
    Full Text:
    properties of the products. New GIC’s containing borate chelate anion such as bis(oxalato)borate, CxB[OC(O

  • Solution deposition and characterization of the thin film inorganic materials

    Creator:
    Özmen, Bahar
    Abstract:
    The general emphasis of this work has been synthesis, characterization, and applications of n- and p-type inorganic oxide thin films that are deposited from solutions. In particular, a study of n-type transparent semiconductor films of tin (IV) oxide and zinc-doped tin (IV) oxide has been performed by spin coating. Solution...
    Resource Type:
    Masters Thesis
    Full Text:
    ....................................................................................................................6 2.1 Unit cell of the crystal structure of SnO2. Large circles indicate O atoms and the small

  • Development, validation and the application of a congener specific photodegradation model for PBDEs

    Creator:
    Zeng, Xia
    Abstract:
    The thermodynamic properties of 39 PBDEs have been calculated using Gaussian 03 on the B3LYP/6-31G(d)//B3LYP/6-31G(d) level. The PBDE congeners' enthalpies of formation increase with increasing number of bromines and show a strong dependence on the bromine substitution pattern. The effects of bromine substitution pattern have been quantitatively studied by GAM...
    Resource Type:
    Dissertation
    Full Text:
    .; Broman, D.; Gustafsson, O., Soot-water distribution coefficients for polychlorinated dibenzo-p-dioxins

  • Studies toward the synthesis of halichlorine and pinnaic acid

    Creator:
    Korf, Eric A.
    Abstract:
    Three approaches toward the core of halichlorine and pinnaic acid are described. The first approach entails a racemic transannular nitrone-olefin [3+2] cycloaddition from nitrone 238. Construction of the nitrone 238 began with aldehyde 241. Another key feature in this route involved a ring-closing metathesis for the formation of a 14-membered...
    Resource Type:
    Dissertation
    Full Text:
    approved: James D. White Three approaches toward the core of halichlorine and