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  • New Treatments for HIV and Cancer: Uncovering Bioactive Compounds from Small Molecule Sources

    Creator:
    Overacker, Ross D.
    Abstract:
    Small molecule drugs have been instrumental in our fight against diseases, beginning when some of the earliest ancient cultures used plant remedies to treat illnesses. More recently, the skill of isolating and characterizing the active ingredients within bioactive plants and microbial extracts has led to the isolation and design of...
    Resource Type:
    Dissertation
    Full Text:
    Streptomyces sp. bacterium resulted in the first report of nanomolar anti-HIV activity from the natural

  • New Graphite Intercalation Chemistry with Alkaline Earth Metals

    Creator:
    Xu, Wei
    Abstract:
    Novel graphite intercalation compounds (GICs) and associated chemistry have been explored, specifically: (1) containing alkyl- substituted imidazolium cations; (2) a series containing alkaline earth metal (Mg, Ca, Sr, Ba) cations with ethylenediamine (en) co-intercalates; (3) showing reversible intragallery M-M bonding and (4) via electrochemical intercalation of Mg cations with potential...
    Resource Type:
    Dissertation
    Full Text:
    (II) ion complexes, [M(en)2] 2+ . We report here facile interconversion between dimeric-M(I) and

  • Porous metal-organic materials for gas capture

    Creator:
    Rookard, Tanner Daniel
    Abstract:
    Metal-organic polyhedra (MOPs) are discrete molecules comprised of a metal and interconnecting ligands. The resulting MOP structures are porous cages, and to date, they have shown great promise toward gas capture. Ammonia is a hazardous gas that is produced in enormous quantities for use in fertilizers. In this talk, I...
    Resource Type:
    Capstone Project
    Full Text:
    . IPCC, 2018: Summary for Policymakers. In: Global Warming of 1.5°C. An IPCC Special Report on the