Index Catalog // ScholarsArchive@OSU

A stereochemically controlled approach to the morphine alkaloids: racemization of 8,9-benzo-4,5-dihydro-6,7-pyrido[4,3-d] oxanin-3(2H)-ones

Creator:: Runyan, Mark T.
Abstract:: A method for the control of absolute stereochemistry in morphine syntheses has been demonstrated by the resolution and efficient racemization of the advanced morphine precursor , 9-methoxy-3-methyl-5,6-dihydro-3H-benzofuro[3,2-e]isoquinoline- 7(7aH)-one, I. This was accomplished by the facile coversion of optically resolved I to its ring opened form, 5,6,7,8-tetrahydro-10-methoxy-3-methyl-7-oxo[1]benzoxonino[ 6,7-c]pyridinium tosylate, II, (Equation...
Resource Type:: Masters Thesis
Full Text:: alkaloids: racemization of 8,9-benzo-4,5-dihydro-6,7-pyrido[4,3-d] oxanin-3(2H)-ones AN ABSTRACT OF THE

Advanced studies on the biosynthesis of the streptolidine moiety of streptothricin F

Creator:: Jackson, Michael D.
Resource Type:: Dissertation
Full Text:: Moiety of Streptothricin F AN ABSTRACT OF THE THESIS OF Michael D. Jackson for the degree of Doctor of

Part I : development and application of an arsenic speciation technique using ion-exchange solid phase extraction coupled with GFAAS ; Part II : investigation of zinc amalgam as a reductant

Creator:: Bos, Mark C.
Abstract:: Two related techniques, based upon ion-exchange solid phase extraction, have been developed for the determination of arsenic speciation. The inorganic arsenic species arsenite (As(III)) and arsenate (As(V)) are separated by anion-exchange and detected with graphite furnace atomic absorption spectrophotometry (GFAAS) with a nickel matrix modifier. The first separation technique, which...
Resource Type:: Masters Thesis
Full Text:: Ion-Exchange Solid Phase Extraction Coupled with GFAAS Mark C. Bos and James D. Ingle Jr

Synthetic studies on marine natural products : I. Stereoselective synthesis of E,Z-1,3-Dienes by tandem nucleophilic addition to a dienylphosphonium salt followed by Wittig reaction. II. Synthesis of cyclopropyl oxylipins by a cation mediated carbocyclization

Creator:: Jensen, Mark S.
Resource Type:: Dissertation
Full Text:: ABSTRACT OF THE DISSERTATION OF Mark S. Jensen Jr. for the degree of Doctor of Philosophy in Chemistry

Synthesis of novel ambifunctional atropisomeric 2,2',6,6'-tetrasubstituted biphenyls and investigation of their properties and organocatalytic activity

Creator:: Sephton, Mark Alan
Abstract:: Ambifunctional axially chiral 2,2',6,6'-tetrasubstituted biphenyls containing nucleophilic (or basic) functional groups juxtaposed with hydrogen-bond donors were synthesized and their properties studied. Applications for the prepared biaryls as potential organocatalysts for enantioselective carbon-carbon bond forming reactions were examined. Processes investigated included: aldol, Michael, nitroaldol (Henry), and Baylis-Hillman reactions. The novel amidoamine...
Resource Type:: Dissertation
Full Text:: AN ABSTRACT OF THE DISSERTATION OF Mark Alan Sephton for the degree of Doctor of Philosophy

The cyclization reactions of certain 5-amino-4-chloro-6-hydrazinopyrimidines with phosgene

Creator:: Krackov, Mark Harry
Resource Type:: Dissertation
Full Text:: -HYDRAZINOPYRIMIDINES WITH PHOSGENE by MARK HARRY KRACKOV A THESIS submitted to OREGON STATE UNIVERSITY in

Studies on the catalytic dehydrogenation of borneol

Creator:: Bocek, Max Mark
Resource Type:: Masters Thesis
Full Text:: BORNEOL by MAX MARK BOCEK A THESIS submitted to the OREGON STATE COLLEGE in partial

Studies towards the total syntheses of (+)-phomactins A, D and G

Creator:: Schwartz, Keith D.
Abstract:: Studies towards the total synthesis of (+)-Phomactin A (1), D (6), and G (9), fungal metabolites with unique molecular architecture and pronounced biological activity, are described. These studies resulted in the synthesis of advanced intermediates 354 and 356, which contain all of the carbon atoms of 1, 6 and 9....
Resource Type:: Dissertation
Full Text:: DISSERTATION OF Keith D. Schwartz for the degree of Doctor of Philosophy in Chemistry presented

Atropisomeric 8,8'-biquinolyl derivatives : synthesis, properties and applications

Creator:: Milicevic, Selena D.
Abstract:: 7,7'-Dihydroxy-8,8'-biquinolyl (azaBINOL) was prepared from 7-hydroxyquinoline via N,N-dimethyl O-quinol-7-yl carbamate by directed ortho-metallation followed by FeCl₃-mediated oxidative coupling of the 8-lithioquinoline intermediate. Saponification of the resulting dicarbamate provided crystalline (±)-azaBINOL in 56% overall yield. 6,6'-Bis(dimethylaminocarbonyl)-7,7'-dihydroxy-8,8´-biquinolyl was prepared from the same dicarbamate by a double anionic-Fries rearrangement in 43% yield. 7,7'-Bis(diethylamino-carbonyloxy)-6,6'-diiodo-8,8´-biquinolyl...
Resource Type:: Dissertation
Full Text:: DISSERTATION OF Selena D. Milicevic for the degree of Doctor of Philosophy in Chemistry presented on

Synthesis and oligomerization of Delta, 4-diamino-2-oxo-1(2H)-pyrimidinehexanoic acid

Creator:: Huang, Sung-ben
Resource Type:: Dissertation
Full Text:: Delta,4-diamino-2-oxo-1(2M- pyrimidinehexanoic Acid Abstract approved: Redacted for Privacy Dwight D

Synthetic studies on marine natural products : Part 1. Synthesis of the sesquiterpenoid dihydropallescensin D via manganese(III)- mediated carbocyclization. Part 2. Approaches toward the synthesis of prianosin and discorhabdin alkaloids

Creator:: Yager, Kraig M.
Resource Type:: Dissertation
Full Text:: . Synthesis of the sesquiterpenoid dihydropallescensin D via manganese(III)- mediated carbocyclization. Part 2

Approaches toward synthesis of the mycosporins

Creator:: Cammack, Janice H.
Abstract:: The mycosporins, formerly called P310's are secondary metabolites of fungi closely associated with fungal reproductive processes that require light. The structurally related iminomycosporins are found in marine plants and animals and may also have functions related to light. In this study, approaches toward the asymmetric synthesis of the mycosporins are...
Resource Type:: Dissertation
Full Text:: . James D. White Abstract approved: The mycosporins, formerly called P310's are secondary metabolites

Design, development and optimization of a fluorometric reaction-rate instrument and method of analysis for metal ions

Creator:: Wilson, Robert Loren
Abstract:: The design, construction and operation of a fluorometric reaction rate instrument is described. The instrument is designed for simple operation with maximum versatility. Advantages and modes of operation of the system are discussed in detail. The instrument is used for the kinetics-based determination of trace levels of Ag and Al....
Resource Type:: Dissertation
Full Text:: the above mechanisms are in agreement with the experimental rate law d[S20:1 dt 16 = k[S208

Proton-neutron-hole states in antimony isotopes populated in the beta decay of ¹²⁸SN and ¹³⁰SN

Creator:: Nunnelley, Lewis Lee
Abstract:: ¹³⁰ Sn and ¹²⁸Sn were separated from mixed fission products. The decay of these isotopes were studied with Ge(Li), LEPS, and plastic scintillator detector systems in single and two parameter coincidence modes. The decay scheme constructed for ¹²⁸Sn decay has levels at 0.0 (5+), 45.7 (4+), 77.8 (3+), 152.9 (2+),...
Resource Type:: Dissertation
Full Text:: -polarization was used to try to explain the hindrance in the 6 decay of a d3/2 neutron to a d 5/2 proton

A reaction rate determination of aluminum with a microcomputer-based spectrofluorometer

Creator:: Campi, Gregory Louis
Abstract:: The development and optimization of a fluorometric reaction rate method for the determination of aluminum is described. Modifications to existing instrumentation permit automatic monitoring and reporting of measurement conditions. Automatic correction of measured analytical signals is provided if monitored parameters deviate from optimum values. A computer controlled standard addition procedure...
Resource Type:: Masters Thesis
Full Text:: ALUMINUM WITH A MICRO- COMPUTER BASED SPECTROFLUOROMETER Abstract approved: Redacted for Privacy J. D

Determination of trace concentrations of cobalt via lucigenin chemiluminescence

Creator:: Montano, Laurence Alan
Abstract:: The application of lucigenin chemiluminescence for the determination of trace concentrations of Co(II) is described. This method is based on the enhancing effect that Co(II) has on the reaction of lucigenin and hydrogen peroxide in a basic solution. The chemiluminescence signal from a Co(II) enhanced lucigenin reaction, which is in...
Resource Type:: Masters Thesis
Full Text:: Description a sample module b PMT module c sample module lid d Swagelock injection port e hinge f access

Applications of redox indicators for evaluating redox conditions in environmental samples

Creator:: Jones, Brian Dion
Resource Type:: Dissertation
Full Text:: Conditions in Environmental Samples AN ABSTRACT OF THE THESIS OF Brian D. Jones for the degree of Doctor

Applicability of the Diels-Alder reactions of o-quinones towards the synthesis of quassinoids and preparation of oxygenated benzeneacetic acids

Creator:: Stirchak, Eugene P.
Resource Type:: Dissertation
Full Text:: . Dwight D. Weller Abstract Approved: The reactions of 3,5-disubstituted o-quinones (59a, 59c) and 4

Development of chemostats and use of redox indicators for studying redox transformations in biogeochemical matrices

Creator:: Lemmon, Teresa L.
Resource Type:: Dissertation
Full Text:: Matrices. Abstract approved. James D. Ingle Jr. Two sophisticated reactor systems were developed for

A microcomputer automated anodic stripping voltammetric analyzer for trace heavy metal speciation

Creator:: Dewald, Lamar Robert
Abstract:: An automated instrument based on a single-board microcomputer was developed for use in voltammetric analyses. Operator input of numerous experiment parameters allows any type of voltammetric analysis to be implemented and multiple scans to be run unattended. A three operational amplifier potentiostat is used to control the cell voltage and...
Resource Type:: Dissertation

Tandem intramolecular photocycloaddition-retro-Mannich fragmentation as a route to indole and oxindole

Creator:: Li, Yang
Abstract:: Irradiation of a tryptamine linked through its side-chain nitrogen to an alkylidene malonate residue results in an intramolecular [2 + 2] cycloaddition to the indole 2,3-double bond. The resultant cyclobutane undergoes spontaneous retro-Mannich fission to produce a spiro[indoline-3,3-pyrrolenine] with relative configuration defined by the orientation of substituents in the transient...
Resource Type:: Dissertation
Full Text:: approved: James D. White

Design and development of an intensified diode array system and its application to new fluorometric reaction rate methods of analysis

Creator:: Ryan, Mary Andrieu
Abstract:: Improvements in instrumentation for fluorometric kinetic measurements and the application of a new intensified diode array (IDA) rapid scanning system to low level transient fluorescence measurements are reported. This instrumentation is applied to a new fluorometric kinetic method for thiamine (TM). Modifications to the existing fluorometric reation rate instrument include...
Resource Type:: Dissertation
Full Text:: FLUOROMETRIC REACTION RATE METHODS OF ANALYSIS Redacted for Privacy Abstract approved: J. D. Ingle, Yr

The development and characterization of miniature spectrometers for measuring the redox status of environmental samples

Creator:: Cantrell, Kevin
Abstract:: A spectrometer, here denoted a Simple, Low-power, Inexpensive. Microcontroller-based or SLIM spectrometer. was developed that exploits the small size and low cost of solid-state electronic devices. This approach results in customizable spectrometers that are considerably less expensive and smaller than traditional instrumentation. The performance of the SLIM spectrometer was evaluated...
Resource Type:: Dissertation
Full Text:: approved: James D. Ingle, Jr. A spectrometer, here denoted a Simple, Low-power, Inexpensive

Fiber optic sensors and spectrometry for the detection of volatile gem-polyhalogenated hydrocarbons

Creator:: Louch, Jeff
Abstract:: A fiber optic fluorometer utilizing a double-fiber optic probe was constructed. The absolute fluorescence signal and effective collection efficiency are approximately one fifth those of typical cuvette fluorometers and agree with those predicted by theory. A quinine sulfate calibration curve shows linearity from a detection limit of 10 pg/mL to...
Resource Type:: Dissertation
Full Text:: Privacy James D. Ingle, Jr. A fiber optic fluorometer utilizing a double-fiber optic probe was

Continuous sample flow and mercury (II) speciation studies utilizing the cold vapor atomic absorption method for mercury determination

Creator:: Oda, Carl Ekio
Resource Type:: Masters Thesis
Full Text:: for Mercury Determination Redacted for Privacy Abstract approved: James D. Ingle, Jr., Associate

Approaches to the synthesis of methymycin

Creator:: Raghavan, Palaykotai Rajagopalan
Abstract:: Several approaches to the synthesis of methymycin were investigated. Segment A (39), containing functionality corresponding to C-9, 10, and 11 of methynolide was made in six steps from propionaldehyde in an overall yield of 37%. Oxidation of 34 with silver nitrate gave 35 which, upon hydroxylation with hydrogen peroxide, gave...
Resource Type:: Dissertation
Full Text:: approved: Dr. James D. White Several approaches to the synthesis of methymycin were investigated

Evaluation of fungal amylases for saccharifying fermentation mashes

Creator:: Cormack, James Frederick
Resource Type:: Dissertation
Full Text:: ACKNOWLEDGMENT I would like to express my deepest appreciation to Dr. H. D. Reese for the guidance and

Development of methodology and instrumentation for determination of chloroform in water

Creator:: Yang, Ying, 1969-
Resource Type:: Dissertation
Full Text:: the Determination of Chloroform in Water Abstract approved: James D. Ingle, Jr. Spectrophotometric

An approach toward the synthesis of euonyminol and cathedulin K- 19

Creator:: Shin, Hyunik
Abstract:: A synthetic approach toward the two major fragments of cathedulin K-19, euonyminol (4) and dimethyl cathate (69), was investigated. Synthesis of dimethyl cathate was accomplished in 3 steps starting from 73. Efforts directed towards the synthesis of euonyminol, a highly oxygenated dihydroagarofuran sesquiterpene, was advanced to a stage in which...
Resource Type:: Dissertation
Full Text:: , Chaehee, and Jaesoon Acknowledgements I would like to sincerely thank professor James D. White for the

Synthetic studies on natural products : Part I. The total synthesis of ±-euonyminol and ±-3,4-dideoxymaytol : Part II. The absolute configuration and enantioselective synthesis of curacin A

Creator:: Kim, Tae-Seong
Resource Type:: Dissertation
Full Text:: Synthesis of Curacin A . Abstract approved: James D. White Part I. The determination of the absolute

Synthetic studies on necic acids of pyrrolizidine alkaloids

Creator:: Lee, Nadine Chauyi
Resource Type:: Dissertation
Full Text:: . Dillon, Neal J. Green, Yoshio Takeuchi, Mitchell D. Nambu, Randy W. Jackson, Neil S. Cutshall, Mark A

Intramolecular diels-alder cycloadditions of citraconic and mesaconic esters ; Studies on the synthesis of the northwest and southeast segments of boromycin

Creator:: Sheldon, Bernard Gale
Resource Type:: Dissertation
Full Text:: BOROMYCIN Redacted for privacyAbstract approved: Dr. James D. White The thermal cycloaddition of trans

Solid-phase synthesis and biophysical testing of uncharged acyclic oligonucleotide analogues

Creator:: Nelson, Jeffrey Stephen, 1962-
Resource Type:: Dissertation
Full Text:: and Biophysical Testing of Uncharged Acyclic Oligonucleotide Analogues. Abstract approved: Dwight D

Low temperature thermal analysis of some boron halide complexes with weak Lewis bases

Creator:: Lerch, Ronald Edwin
Abstract:: Thermal analysis was used to investigate the following seven systems: H₂S-B₂F₄, SOF₂-B₂F₄, COC1₂-B₂F₄, SF₄-B₂F₄, Xe-BF₃, NF₃-BF₃, and NF₃-BC1₃. In two of the seven systems compound formation was observed. In the system, H₂S-B₂F₄ the compounds H₂S[superscript .]B₂F₄ and 2H₂S[superscript .]B₂F₄ are formed. The compound H₂S[superscript .]B₂F₄ has a melting point of...
Resource Type:: Dissertation
Full Text:: complexes with weak Lewis bases AN ABSTRACT OF THE THESIS OF RONALD EDWIN LERCH for the Ph. D. in

Trace element abundances in automobile exhaust particulate

Creator:: Jones, Roger A.
Resource Type:: Masters Thesis
Full Text:: Redacted for Privacy Abstract approved: Walter D. Loveland The trace element abundances in automobile

Analytical and mechanistic studies of the chemiluminescence oxidation of hydroxy-containing compounds

Creator:: Vasquez de Montalvo, Socorro I.
Abstract:: This thesis is concerned with the development and use of routine analysis techniques based on chemiluminescence (CL) detection for: 1) ethanol in gin down to the 0.3% (v/v) level; 2) the antioxidants propyl gallate and BHA in lard to levels as low as 0.3 and 0.2 mg/L, respectively; 3) pyrogallol...
Resource Type:: Dissertation
Full Text:: in lard c) pyrogallol (Py) in hair dye d) vanillin in vanilla extract Most mechanistic studies

Application of flow injection analysis to enzymatic fluorescence kinetic methods

Creator:: Elliott, Colin Bruce
Abstract:: Studies of the use of NADH as the monitored fluorophore for enzymatic fluorescence kinetic methods are discussed. Interference studies for the detection of NADH and the adaptation and optimization of fluorescence kinetic measurements to four serum assays are also described. A microcomputer-controlled flow injection analysis (FIA) system was designed and...
Resource Type:: Dissertation
Full Text:: Enzymatic Fluorescence Kinetic Methods Redacted for Privacy Abstract approved: -- James D. Ingle Jr

Part I : synthesis of azetidin-2-ones from pyrazolidin-3-ones ; Part II : synthesis of a subunit of the immunosuppressant FK-506

Creator:: Toske, Steven Gerald
Resource Type:: Dissertation
Full Text:: Immunosuppressant FK-506. Abstract approved: James D. White Part I. A new route for the preparation of azetidin-2

A critical comparison of methods for the determination of phytoplankton chlorophyll

Creator:: Salinas, John T.
Abstract:: The concentration of chlorophyll in natural bodies of water is commonly determined as a means to rapidly estimate the phytoplankton biomass. The literature gives numerous warnings, however, as to the problems involved with accurately determining chlorophyll concentrations. The author's work at Crater Lake, Oregon enticed him to explore critically the...
Resource Type:: Masters Thesis
Full Text:: . James D. Ingle, Jr. The concentration of chlorophyll in natural bodies of water is commonly determined

Synthetic studies n bioactive natural products. Part I, An approach towards the nootrophic agent huperzine A. Part II, Synthesis of the tricarbonyl subunit of rapamycin

Creator:: Jeffrey, Scott C.
Resource Type:: Dissertation
Full Text:: Rapamycin. Abstract approved: James D. White Part I. Two approaches towards the bicyclic framework of

Microcomputer-based fluorometric kinetic determination of ascorbic acid and flow injection analysis methods for interference correction and kinetic determinations based on the peak profile

Creator:: Chung, Hyung-Keun
Resource Type:: Dissertation
Full Text:: Determinations Based on the Peak Profile Redacted for privacy Abstract approved: James D. Ingle, Jr. A

Design, characterization, and application of spectrometers for determination of low-level dissolved oxygen with small-volume sampling methodology

Creator:: Cakin, Defne
Abstract:: New analytical methods and instrumentation were developed for the determination of dissolved oxygen (DO) at low concentrations in water. The methods were based on monitoring the absorbance increase due to the oxidation of reduced indigo carmine (IC) by oxygen in the sample in different types of spectrometer cells. Spectrophotometer cells...
Resource Type:: Dissertation
Full Text:: : ___________________________________________ James D. Ingle, Jr. New analytical methods and instrumentation were developed for the

Analytical chemiluminescence measurements and instrumentation

Creator:: Marino, Dean Frank
Resource Type:: Dissertation
Full Text:: system (hardware and software), capable of analog to digital (A/D) peak height and area measurements

Total synthesis of phorboxazole A

Creator:: Lee, Tae Hee
Abstract:: The total synthesis of a highly potent cytotoxic marine natural product, phorboxazole A, is described. Both a palladium(II)-mediated and a palladium(II)-catalyzed intramolecular alkoxycarbonylation were used as key steps for the preparation of the two cis-2,6-disubstituted tetrahydropyran rings (C22-C26 and C11-C15) of phorboxazole A. The synthesis used a convergent approach involving...
Resource Type:: Dissertation
Full Text:: : James D. White The total synthesis of a highly potent cytotoxic marine natural product

Studies toward the total synthesis of (+)-providencin

Creator:: Jana, Somnath
Abstract:: Studies toward the total synthesis of (+)-providencin (1), a highly oxygenated cembranoid dipterpene with a unique bicyclo[12.2.0]hexadecane skeleton and pronounced biological activity, are described. These studies resulted in the synthesis of advanced intermediates 320 and 332 which contain all of the carbon atoms of 1. In a first generation approach...
Resource Type:: Dissertation
Full Text:: approved: _____________________________________________________ James D. White Studies toward

Synthetic studies on the macrolide antibiotic rutamycin B

Creator:: Wang, Shan
Resource Type:: Dissertation
Full Text:: approved: J James D. White Part I. Five approaches, including two successful routes, toward the

Multielement atomic absorption and fluorescence spectrometry

Creator:: Salin, Eric Dunbar
Abstract:: A multielement spectrometer has been developed for the simultaneous determination of four elements by atomic absorption (AA) or atomic fluorescence (AF). The spectrometer is based on a multiple exit slit monochromator and uses a mirrored funnel to direct light from the various exit slits to a single photomultiplier. There are...
Resource Type:: Dissertation
Full Text:: ABSORPTION AND FLUORESCENCE SPECTROMETRY Redacted for Privacy Abstract approved: J. D. Ingle, Jr. A

Microcomputer controlled chemical and radiochemical separations and analysis

Creator:: Bennett, Casey Wayne
Abstract:: An automated radiochemical flow analysis (ARFA) system was developed which integrates chemical and radiochemical techniques into one system through the use of a microcomputer. The operator, through the microcomputer, controls valves and pumps to transfer sample and reagent solutions to counting loops, ion exchange columns and holdup reservoirs. A Ge(Li)...
Resource Type:: Dissertation
Full Text:: Radiochemical Separations and Analysis Abstract approved: Redacted for Privacy James -D. Ingle, Jr

Two studies concerning rare earth elements : I. Rare earth DTPA complexes as estuarine hydrological tracers : II. Rare earth elemental concentrations in some Pacific Northwest rivers

Creator:: Keasler, Kenneth M.
Abstract:: Two studies were conducted involving rare earth elements. In the first study, the use of rare earth diethylenetriaminepentaacetic acid (DTPA) complexes as stable actiable tracers, a method of stable-isotope tracing with post-sampling neutron activation analysis, was explored. The persistence of rare earth DTPA complexes in estuarine waters was measured in...
Resource Type:: Masters Thesis
Full Text:: in some Pacific Northwest Rivers. Abstract approved: Redacted for Privacy Walter D. Loveland Two

Cis-2,5-diaminobicyclo[2.2.2]octane : a novel C₂-symmetric scaffold for asymmetric catalysis

Creator:: Shaw, Subrata
Abstract:: This thesis describes the development of a new enantioselective synthetic method employing chiral cis-2,5-diaminobicyclo[2.2.2]octane-based organometallic catalysts. The significance of this new method to organic synthesis is illustrated with preparation of enantioenriched products that are transformed to important pharmaceutical agents. Chapter 1 provides a brief historical overview of asymmetric catalysis, especially...
Resource Type:: Dissertation
Full Text:: [2.2.2]octane: A Novel C2-Symmetric Scaffold for Asymmetric Catalysis Abstract approved: James D

Characterization and applications of polyphenol chemiluminescence reactions and flow cell instrumentation

Creator:: Miller, Robert J. (Robert James), 1933-
Resource Type:: Dissertation
Full Text:: approved: Redacted for Privacy James D. Ingle, Jr. This thesis encompasses the development of direct

Monitoring redox conditions with redox indicators during microbial reductive dechlorination in microcosms and bioaugmented columns

Creator:: Ruiz-Haas, Peter A.
Abstract:: New methods, sensors, and devices based on redox indicators were developed to monitor redox conditions in anoxic and anaerobic laboratory systems and the subsurface environment. The primary application was monitoring redox conditions during the dechlorination of tetrachioroethene (PCE) to ethene (ETH) in packed columns and microcosm bottles containing an enriched...
Resource Type:: Dissertation
Full Text:: Columns. Abstract approved: James D. Ingle, Jr. New methods, sensors, and devices based on redox

A mechanistic study of the distribution of amphiphilic organic compounds between water and organic sorbents

Creator:: Zhang, Wanjia
Resource Type:: Dissertation
Full Text:: discussion. To my committee members, especially to Dr. James D. Ingle for his kindness, understanding and

The kinetic and radiolytic aspects of control of the redox speciation of neptunium in solutions of nitric acid

Creator:: Precek, Martin
Abstract:: Neptunium, with its rich redox chemistry, has a special position in the chemistry of actinides. With a decades-long history of development of aqueous separation methods for used nuclear fuel (UNF), management of neptunium remains an unresolved issue because of its not clearly defined redox speciation. Neptunium is present in two,...
Resource Type:: Dissertation
Full Text:: to the past and present members of my doctoral committee at OSU: Dr. James D. Ingle, Dr. Walter D

Photoelectron spectroscopy of small molecules

Creator:: Bomben, Kenneth D.
Abstract:: The photoelectron spectra of a series of halogenated molecules have been investigated in the gas phase. Both core-ionization energies and Auger kinetic energies were measured to probe the nature of the interaction that holds a core electron to the molecule. It was found that satellite structure (shake) could be used...
Resource Type:: Dissertation
Full Text:: OF THE THESIS OF Kenneth D. Bomben for the degree of Doctor of Philosophy in Chemistry presented on

New Treatments for HIV and Cancer: Uncovering Bioactive Compounds from Small Molecule Sources

Creator:: Overacker, Ross D.
Abstract:: Small molecule drugs have been instrumental in our fight against diseases, beginning when some of the earliest ancient cultures used plant remedies to treat illnesses. More recently, the skill of isolating and characterizing the active ingredients within bioactive plants and microbial extracts has led to the isolation and design of...
Resource Type:: Dissertation
Full Text:: -rich DNA. (A) Actinomycin D (4.1) was tested at 0.03, 0.10, 0.20, 0.40, 1.00, 2.00, and 3.00 µM. (B

High resolution ionization-detected simulated Raman spectroscopy

Creator:: Crew, Marshall D.
Abstract:: A new experimental apparatus was built at Oregon State University to perform high resolution stimulated Raman spectroscopy in a pulsed molecular jet at state densities of the order of 10¹¹ cm⁻³. The technique uses a stimulated Raman step to first populate a vibrational/rotational level and then a resonantly enhanced multiphoton...
Resource Type:: Dissertation
Full Text:: AN ABSTRACT OF THE THESIS OF Marshall D. Crew for the degree of

Abiotic and biological transformation of TBOS and TKEBS, and their role in the biological transformation of TCE and c-DCE

Creator:: Vancheeswaran, Sanjay
Abstract:: At Site-300, Lawrence Livermore National Laboratory (LLNL), CA, trichloroethene (TCE) is present along with tetraalkoxysilanes such as tetrabutoxysilane (TBOS) and tetrakis(2-ethylbutoxy) silane (TKEBS), as subsurface contaminants. Intrinsic transformation of TCE to cis-dichloroethene (c-DCE) was observed in the groundwater at locations co-contaminated with TBOS or TKEBS. Attenuation of TBOS and TKEBS...
Resource Type:: Masters Thesis
Full Text:: , Ying, Lutz, George, Matt, Jason, Merf, Young, Sarun, Pardi, Dave, Mark, Mohammad) who have

Wide band gap semiconductors and insulators : synthesis, processing and characterization

Creator:: Hersh, Peter A.
Abstract:: The work presented here is focused on applying basic principles of solid-state chemistry to the study and development of new wide band-gap semiconductors and insulators for photovoltaic and electronic-device applications. Analysis of crystal structure, band structure, optical band gap, morphology and transport properties provides fundamental insight into materials performance as...
Resource Type:: Dissertation
Full Text:: Watson for his expertise on surface chemistry, and Dr. Mark Zabriskie for his time and patience. I

Exploring the Distinct Solution Behavior of Isostructural Polycoltanates

Creator:: Fullmer, Lauren
Abstract:: Polyoxometalates are a rapidly growing class of discrete metal oxide clusters with a wide range of applications including functional materials. These anionic clusters of the group V and VI transition metals are inexpensive and non-toxic. Within group V polyoxometalates, niobium and tantalum chemistry has been underdeveloped owing to their unique...
Resource Type:: Dissertation
Full Text:: Information for Chapter 6………………………………………109 C. Supporting Information for Chapter 7………………………………………127 D

Quantitative determination of emerging contaminants, solvent stabilizers and fullerene nanomaterials, in biological and environmental systems

Creator:: Isaacson, Carl W.
Abstract:: To determine the impact of emerging environmental contaminants on human and environmental health, quantitative analytical methods are required. Analysis of emerging contaminants is hampered by their widely varying physical-chemical properties. Therefore quantitative analytical methods must be developed to determine the behavior of emerging contaminants in environmental systems. A quantitative analytical...
Resource Type:: Dissertation
Full Text:: committee members (Douglas Barofsky, James Ingle, and Mark Dolan) for their investment of time and support

Hydrophobicity, Anion Exchange, and Phytoaccumulation of Per- and Polyfluoroalkyl Substances (PFAS): Retention and Remediation

Creator:: Parker, Bethany A.
Abstract:: Per- and polyfluoroalkyl substances (PFAS) are a group of contaminants of great concern due to their toxicity and ubiquity in the environment. Remediation efforts historically have focused on granular activated carbon (GAC) because of its low maintenance and relatively low cost. However, GAC is not PFAS selective and is especially...
Resource Type:: Dissertation
Full Text:: , D. R. U.; Chiang, S. Y. D.; Pohlmann, D.; Varley, C.; Bodour, A.; Field, J. A., Pilot scale

Polycyclic Aromatic Hydrocarbons in Atmospheric Fine Particulate Matter: Beyond the Priority Pollutant List

Creator:: Kramer, Amber L.
Abstract:: Atmospheric fine particulate matter (PM2.5) has been linked to the death of 7 million people per year around the planet. The organic portion of PM2.5 is responsible for increases in oxidative stress, inflammation, mutation and carcinogenesis. Anthropogenic activity releases more organic material into the atmosphere, and has increased the amount...
Resource Type:: Dissertation
Full Text:: , Claudia Meier, Mark Dolan, Alla Zelenyuk, and Stephen Giovannoni for their patience and guidance through

Investigations of two chemical systems relevant to pyroprocessing used nuclear fuel

Creator:: Hames, Amber
Abstract:: Pyroprocessing is an advanced technology for recycling used nuclear fuel. Pyrochemical processes encompass a wide range of chemical, physical, and electrochemical methods to partition fission products and other components from used nuclear fuel, which allows for the reuse of the actinides in nuclear fuel. This dissertation investigates two chemical systems...
Resource Type:: Dissertation
Full Text:: , Dr. Joseph Lapka, Dr. M. Alex Brown, and Dr. Brian Gullekson. To Dr. Mark Williamson, my Argonne

Expanding the scope of a Diels-Alder approach to biaryl synthesis

Creator:: Schwartz, Johanna Perkins
Abstract:: A Diels-Alder approach to biaryls (DAB) has been applied towards the synthesis of highly substituted, programmable biaryl templates. Tri- and tetra-ortho-substituted biaryls can be produced in just three to four steps from commercially available materials utilizing the Diels-Alder [4+2] cycloaddition. The methods described herein will illustrate the ability of mono...
Resource Type:: Dissertation
Full Text:: , Prof. Paul R. Blakemore, Prof. Kevin P. Gable, Prof. Mark Zabriskie, and Prof. Kaichang Li for their

Prediction and Measurement of Polycyclic Aromatic Hydrocarbons (PAHs) Transformation Products in the Environment.

Creator:: Titaley, Ivan A.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are a group of environmental contaminants consisting of fused benzene rings. Parent-PAHs, methylated-PAHs (MPAHs), and PAHs with molecular weight of 302 a.m.u (MW302-PAHs) are considered as unsubstituted-PAHs. These unsubstituted-PAHs undergo transformation reactions resulting in the formation of PAH-transformation products (PAH-TPs), or substituted-PAHs, including nitrated-, oxygenated-, and...
Resource Type:: Dissertation
Full Text:: Sleszynski, Dr. Sean Burrows, and Dr. Mark Dolan, for providing me with advice for my research projects

Some chemical and physical properties of dry lime-sulfur

Creator:: Bullis, D. E. (DeLoss Everett), 1894-1984
Resource Type:: Masters Thesis
Full Text:: dry lime-sulfur by placing 2.5 grams in a 250 c.c. volumetric flask, making to the mark with water

Searching for new niobium oxide based superconductors

Creator:: Bacon, Paul Eric
Resource Type:: Masters Thesis
Full Text:: . D. A. Keszler Dr. M. M. Lerner Dr. R. T. Mason people from the Sleight group: Dr. Laura King Dr

Fluorinated and deuterated surrogates for quantifying microbial transformation of chlorinated ethenes and ethanes in anaerobic groundwater

Creator:: Ennis, Elliot G.
Abstract:: Chlorinated aliphatic hydrocarbons (CAHs) such as vinyl chloride (VC) and 1,-2 dichioroethane (DCA), are wide-spread groundwater pollutants found at many contaminated field sites around the world. Quantitative tools are needed to determine the in situ rates of VC and DCA transformation to ethene in contaminated groundwater. The objective of this...
Resource Type:: Masters Thesis
Full Text:: OSU: Professors Staci Simonich, Vince Remcho, Richard Nafshun, Nick Drapela, and Mark Dolan for all

Synthesis of Intercalation Compounds and Nanocomposites of Inorganic Layered Hosts

Creator:: Liyanage, Medagama Liyanage Amila Udayanga
Abstract:: Novel synthetic strategies are developed to prepare new intercalation compounds and nanocomposites with several layered hosts (NiPS₃, Na-montmorillonite, MoS₂ and MoO₃). In these products, alkali metals are ionic intercalates and linear polymers, dendrimers or amines act as co-intercalates. In addition to new synthetic approaches, new structures are identified and characterized....
Resource Type:: Dissertation
Full Text:: method contain polymer monolayers (d = 0.42 nm) between host layers, in contrast to the polymer

The urea denaturation of bovine serum albumin, polyglycyl bovine serum albumin and poly-L-phenylalanyl bovine serum albumin

Creator:: Chung, Po-luen
Abstract:: A comparative study was made on the effect of urea denaturation of bovine serum albumin (BSA), polyglycyl BSA and poly-L-phenylalanyl BSA. The denaturation process was followed by ultraviolet spectrophotometry and optical rotation. A blue shift in the absorption maximum at 278 mμ was observed in urea denatured proteins, In 7M...
Resource Type:: Masters Thesis
Full Text:: . 36 37 38 43 10. Effect of urea concentration on specific rotation [ a ] D for native BSA and

Mass spectrometric analysis of proteins and peptides : elucidation of the folding pathways of recombinant human macrophage colony stimulating factor beta

Creator:: Zhang, Yuan Heidi
Abstract:: Recombinant human macrophage colony stimulating factor beta (rhm-CSFβ) is a glycoprotein that stimulates the proliferation, differentiation and survival of cells belonging to the monocyte-macrophage lineage. It contains nine inter-subunit and intra-subunit disulfide bonds and represents an excellent model system for studying disulfide bond formation during protein folding because the assembly...
Resource Type:: Dissertation
Full Text:: catalyzed by GSH/GSSG represented an important isomerization step in folding. A dimeric intermediate, D

Strategic Application of Computations to Diverse Chemical Systems

Creator:: Brueckner, Alexander C.
Abstract:: My work has focused on streamlining the study of organic compound structure, properties, and reactions by 1) understanding and using available computational software, 2) developing software packages to facilitate data manipulation as well as augment public programs, and 3) applying public and in-house developed software to further the understanding of...
Resource Type:: Dissertation
Full Text:: -Javier Barrios Antúnez, Mark D. Greenhalgh, Pilar Elías-Rodríguez, Patrick Roberts, and Thomas H. West

Biosynthesis of blasticidin S : mechanistic and stereochemical investigations

Creator:: Prabhakaran, P. C.
Abstract:: Feeding of [3-¹³C, 2-¹⁵N]arginine, 38a, unequivocally established that the β- arginine moiety of blasticidin S, 1, was formed from α-arginine by an intramolecular migration of the α-amino group to the β- position. Further feedings using chirally deuteriated arginines 38e and 38f revealed that the aminomutase process occurred with inversion of...
Resource Type:: Dissertation
Full Text:: . griseochromogenes have not been successful so far. Feeding [2,3,4,6,6- 2H5] -D- glucose resulted in blasticidin S

Natural and semi-synthetic compounds with biocidal activity against arthropods of public health importance

Creator:: Khasawneh, Mohammad A.
Abstract:: This study identified new compounds with pest control activities. The two sources of candidates that were followed here were the main heartwood extract of Alaska Yellow Cedar (AYC) constituents and several semi-synthetic counterparts. Five compounds were isolated and identified for the first time in AYC heartwood in this research: two...
Resource Type:: Dissertation
Full Text:: these compounds were confirmed on the basis of spectroscopic techniques such as 1- and 2-D NMR, high

Part I: Synthesis and evaluation of synosutine as an inhibitor of serotonin, norepinephrine, and dopamine transporters Part II: Asymmetric approach to the tetracyclic core of neomangicol A

Creator:: Juniku, Rajan B.
Abstract:: Part I: Racemic and asymmetric syntheses of a new substance with prospective antidepressant properties were achieved. In vitro assays with synthetic racemates (±)-25 and (±)-26 suggested that the former is a relatively selective inhibitor of serotonin transporter whereas the latter is a more balanced inhibitor of both serotonin and norepinephrine...
Resource Type:: Dissertation
Full Text:: Abstract approved: _____________________________________________________ James D. White Part I

Removal of Radioactive Strontium, Iodine, and Uranium from Contaminated Groundwater : Sorption Processes and Properties

Creator:: Leonard, Mary E.
Abstract:: Iodine-129 is a key risk driver at sites where nuclear materials have been fabricated or processed, and it is a predominant isotope of concern in long-term waste storage strategies. I-129 exists primarily as iodate in the subsurface at the Hanford Site in south-central Washington State. Between 15 and 40% of...
Resource Type:: Dissertation
Full Text:: coefficient, D, is the ratio of the concentration of a given substance in one phase to its concentration in

Effects of small molecule ligands on the conformational dynamics of the Farnesoid X Receptor ligand binding domain (FXR-LBD)

Creator:: Yang, Liping
Abstract:: The Farnesoid X Receptor (FXR) is a member of the nuclear receptor superfamily of transcription factors that plays a key role in the regulation of bile acids, lipid and glucose metabolisms. The regulative function of FXR is governed by conformational changes of the ligand binding domain (LBD) upon ligand binding....
Resource Type:: Dissertation
Full Text:: ..................................................................................................................................................... 148 Bottom row: Average differences in deuterium percentage (D%) of seven time points

The metabolism of C¹⁴ labeled 2, 4-dichlorophenoxyacetic acid in bean plants

Creator:: Jaworski, Ernest George
Resource Type:: Dissertation
Full Text:: : Redacted for Privacy Prdrerm sf, Ctcclgtry hBartrat & Clar8r of IaJor Redacted for Privacy Bd d

A spectrophotelometric method for the determination of iron

Creator:: Hulett, Henry Russel
Resource Type:: Masters Thesis
Full Text:: calculated by determining the transmittancy at the given wave length. 6 AP±ANATUS AI\D SOLUTIONS o

The separation of zirconium and magnesium by means of ion exchange

Creator:: Lee, Eugene Edward
Resource Type:: Masters Thesis
Full Text:: an . d diluted up to the mark, A fifty milliliter (1.1 ram of zirconium) aliquot of zirconium

The investigation of octaammine-μ-nitro-μ-amidodicobalt (III) nitrate as an analytical reagent for sulfate

Creator:: Dennison, James Eugene
Resource Type:: Masters Thesis
Full Text:: spectrophotometrically. Cobalt complex salts are usually highly colored since the cobalt atom has an incomplete d

The colorimetric determination of niobium with thiocyanate

Creator:: Levitt, Arnold Edward
Resource Type:: Masters Thesis
Full Text:: as the 400 m)i mark is neared, but they were not carried far enough into the ultraviolet reEton to

Using Computational Studies to Characterize Aqueous Metal Clusters : From Spectroscopy to Stability

Creator:: Wills, Lindsay A.
Abstract:: In this dissertation, the spectroscopic properties and thermodynamic stability of a class of materials known as metal oxo and hydroxo clusters are studied. In aqueous solutions, many metals can aggregate into discrete clusters of metals bridged by oxo or hydroxo ligands. These clusters are of particular interest to us for...
Resource Type:: Dissertation
Full Text:: (B) and LSFC spectra of flat Al13 (C, orange), Al7+1 (D, green), and Al7 (E, violet

Development and application of an analytical technique for the determination of methylmercury compounds in environmental samples based on isolation by distillation, followed by purge-and-trap sample concentration and GC/MS separation and detection, after aqueous phase ethylation with sodium tetraethylborate

Creator:: Rice, William R.
Abstract:: An analytical technique has been developed for the determination of methylmercury compounds in environmental samples. The technique is based on a two-stage procedure. In the first stage, methylmercury compounds are isolated from the sample matrix as methylmercury chloride (MeRgCl) by distillation. The distillation procedure is based on a series of...
Resource Type:: Masters Thesis

The colorimetric determination of calcium with ammonium purpurate

Creator:: Moser, James Howard
Resource Type:: Masters Thesis
Full Text:: volumetric flask so that when diluted to the mark with distilled water, the volume percent alcohol

Determination of low level hydrocyanic acid in solution using gas-liquid chromatography

Creator:: Schneider, Carl Rudolph
Resource Type:: Dissertation
Full Text:: (p.s.i.) Plow Rate (cc./min.) Peak Area (cm2) Efficiency (calc*d) w 12.4 13 19.8 83.9 13.1 31

The apparent molal volume of salts in methanol solution

Creator:: Stark, John Benjamin
Resource Type:: Masters Thesis
Full Text:: liquid was in every case adjusted to the mark on the py1ìometer neck in a constant temperature bath

A study of the decomposition of murexide

Creator:: Moser, James Howard
Resource Type:: Dissertation
Full Text:: . E. N, 1arvell and H. D. Reese was Ereatly appreciated. TAELE OF CONTENTS PaEe t

Spectrophotometric determination of cobalt as the trioxalatocobaltate (III)

Creator:: Zeagas, George James
Resource Type:: Masters Thesis
Full Text:: diluted to the mark, shaken thoroughly, and iuediately filtered to remove excess of lead peroxide. The

A spectrophotometric method for the determination of iron with thioglycolic acid

Creator:: Shepherd, Maurice Joseph
Resource Type:: Masters Thesis
Full Text:: thoroughly washing any residue, diluted to the mark, and thoroughly shaken. An aliquot of i ml. was

Measuring in situ reductive dechlorination rates in trichloroethene-contaminated groundwater

Creator:: Hageman, Kimberly J.
Abstract:: Trichloroethene (TCE) is the most frequently detected organic contaminant in groundwater, is classified as a probable human carcinogen, and exhibits toxicological effects on the human endocrine, immune, developmental, and reproductive systems. While significant research efforts have been devoted to the development of strategies for remediating TCE-contaminated groundwater, their advancement is...
Resource Type:: Dissertation
Full Text:: assistance include Ralph Reed, Brian Davis, Jesse Jones, Kevin Tam, Brian Wood, Roy Haggerty, Mark Dolan

The use of 1,10-phenanthroline in a spectro-photometric method for the determination of copper in ores

Creator:: Gruzensky, Paul Milnore
Resource Type:: Masters Thesis
Full Text:: ,, reciprocal of the transmittancy, or the extinction as a function of concentration for a series d of

The paramagnetism of potassium ferrate

Creator:: Hrostowski, Henry John
Resource Type:: Masters Thesis
Full Text:: June 1949 D APPHOVEJJ: Assistant rofes'ior of Chemistry In Charge of Major Head of

Spectrophotometric determination of nickel in steel with potassium dithiooxalate

Creator:: Newby, Bill Joe
Resource Type:: Masters Thesis
Full Text:: diluting up to the mark and thorouL;hly mixing. The spectral tranamission curvos ax'e shown in Fie. I

Zero kinetic energy photoelectron spectroscopy of polycyclic aromatic hydrocarbons

Creator:: Zhang, Jie
Abstract:: In this dissertation, I present electronic spectra of a few polycyclic aromatic hydrocarbons (PAHs): tetracene, pentacene, pyrene, benzo[g,h,i]perylene and benzo[a]pyrene using resonantly enhanced multiphoton ionization (REMPI) and zero kinetic energy (ZEKE) photoelectron spectroscopy. The work of tetracene and pentacene also combine a laser desorption source with a ZEKE spectrometer, demonstrating...
Resource Type:: Dissertation
Full Text:: state as intermediate states: (a) 0 00 , (b) 15 1 , (c) 22 2 15 1 , (d) 15 2 , (e) 14 1 ,and (f

Nonlinear Raman spectroscopy of gases

Creator:: Lundeen, Thomas F.
Abstract:: Applications of several methods of coherent nonlinear Raman Spectroscopy have been made in this thesis research. The theory and potential of one of these, Photoacoustic Raman Spectroscopy (PARS), is discussed in chapter two. Experimental results are presented which illustrate the sensitivity of this method and establish sampling conditions for maximum...
Resource Type:: Dissertation
Full Text:: C. Partial State-to-State Model 99 D. Complete State-to-State Model 107 E. Para H 2 --- He

X-ray structure studies of oriented phospholipid multilayers

Creator:: Lytz, Robert Keith
Abstract:: Lamellar x-ray diffraction was studied from thin films of L-α-1,2-dipalmitoyl lecithin (DPL) and a 1:1 mixture (BrDPL) of L-α-l-palmitoyl-2-(9- bromopaimitoyl) lecithin and its 10-bromo analog. The specimens had high lamellar order, with an upper bound on the mosaicity of 6 mrad (0.4°) for DPL and BrDPL. With various water contents,...
Resource Type:: Dissertation
Full Text:: ) Calibration Perpendicular to Anode . . 26 D. Calibration using Point Source and Mask . . . . 34 E. Position

Metabolism of dl-valine and dl-isovaline in the normal rat

Creator:: Sinnhuber, R. O.
Resource Type:: Masters Thesis
Full Text:: transferred to a 100 cc volumetric flask. By washing down the funnel the saole was made up to the mark. The

Tissue metabolism of guinea pigs deficient in the anti-stiffness factor

Creator:: Simonsen, Donald Howard
Resource Type:: Masters Thesis
Full Text:: filled with mercury to the 150 rim. mark on the closed arm of the manometer. The mercury was removed

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