Index Catalog // ScholarsArchive@OSU

N-D-Glucosylglycine in purine biosynthesis

Creator:: Rogers, Dexter, 1921-
Resource Type:: Dissertation
Full Text:: properties toward bacteria_. Journal of bacteriology 21:299- 303 . 1931 . 6a. Goldthwait , D. A. and R. A

Coriolis analysis of several high-resolution infrared bands of bicyclo[111]pentane-d₀ and -d₁

Creator:: Perry, A., Martin, M. A., Nibler, J. W., Maki, A., Weber, A., and Blake, T. A.
Abstract:: High-resolution infrared absorption spectra have been analyzed for two bicyclo[111]pentane isotopologues, C₅H₈ (-d₀) and C₅H₇D (-d₁), where in the latter the D-atom replaces a hydrogen on the C₃ symmetry axis such that the molecular symmetry is reduced from D₃ₕ to C₃ᵥ. Two (a"₂) parallel bands, v₁₇ and v₁₈, of bicyclopentane-d₀...
Resource Type:: Article
Full Text:: . Weber c, T.A. Blake d aDepartment of Chemistry, Oregon State University, Corvallis, OR 97332-4003

High-resolution infrared studies of perdeutero-spiropentane, C₅D₈

Creator:: Erickson, Blake Alexander, Ju, X., Nibler, Joesph W., Beaudry, C. M., and Blake, T. A.
Abstract:: Perdeutero-spiropentane (C₅D₈) has been synthesized and infrared and Raman spectra are reported for the first time. Wavenumber assignments are made for most of the fundamental vibrational modes. Gas phase infrared spectra were recorded at a resolution (0.002 cm⁻¹) sufficient to resolve individual rovibrational lines and show evidence of strong Coriolis...
Resource Type:: Article
Full Text:: vibration is vib = 5a1 (R) + 3a2 + 4b1 (R) + 5b2 (IR, R) + 8e (IR,R). The infrared and Raman

Large-D limit for correlation methods in atoms

Creator:: Summerfield, John H.
Resource Type:: Dissertation
Full Text:: of Doctor of Philosophy in Chemistry presented on May 26, 1994 Title: Large-D Limit for Correlation

The preparation of d-arginine hydrochloride from salmon testes

Creator:: Ruggles, Judson Gilbert
Resource Type:: Masters Thesis
Full Text:: The preparation of d-arginine hydrochloride from salmon

Synthesis of 2-substituted-5, 8-dihydroxypyrimido (4,5-d) pyridazines

Creator:: McMahill, Paul Edward
Resource Type:: Masters Thesis
Full Text:: Synthesis of 2-Substituted-5,8-Dihydropyrimido (4,5-d

Studies toward the total synthesis of alkaloids : nagelamide A and D, agelastatin D, dragmacidin A-C, salacin and almazoles

Creator:: Tonsiengsom, Sorasaree
Abstract:: Studies toward the total syntheses of highly potent cytotoxic alkaloids including the bromopyrrole alkaloids and indole alkaloids were conducted and are described. Studies carried out in the course of this dissertation consist of five total syntheses of natural products that include bromopyrrole alkaloids nagelamide A, D and agelastatin D as...
Resource Type:: Dissertation
Full Text:: : R = Br agelastatin C 1.9 N NH NH N O O HO H H H H Br agelastatin D 1.10 A B C D HN N

Catalytic desymmetrization of D₂d̳-symmertic proprochiral tetrasubstituted biphenyl compounds: a novel approach to the synthesis of axially chiral C₂-symmetric molecules

Creator:: Gunderson, Jeremey Tyson
Abstract:: Many D2d-symmetric 2,2',6,6'-tetrasubstituted biphenyls are readily prepared via net oxidative dimerization of appropriate 1,3-disubstituted benzenes. Conversion of such proprochiral compounds to useful C2-symmetric chiral biphenyls requires formal replacement of two substituents on opposing aryl ring units with alternate groups. This under exploited desymmetrization tactic has been demonstrated for the generation...
Resource Type:: Masters Thesis
Full Text:: . 16 R OH Cl R' O DCM/Pyr (10:1) 0 oC to rt, 4h + RO R' O 29a-c 30a-c 31a-d Entry Alcohol

Development of Carbenoid Eliminative Cross-coupling for the Stereocontrolled Synthesis of Trisubstituted Alkenyl Moieties Within Styrenes and 1,3-Dienes

Creator:: Tanpure, Subhash D.
Abstract:: Traditional approaches for the direct preparation of alkenes are unable to fully control either the stereochemical configuration of the carbon-carbon double bond or else the regiochemistry of the substituents surrounding it. The recently introduced concept of carbenoid eliminative cross-coupling (CEXC) offers a remedy to these deficiencies by providing for a...
Resource Type:: Dissertation
Full Text:: : ______________________________________________________ Paul R. Blakemore Traditional approaches for the direct preparation of alkenes are

Development of stable x-ray fluorescent tracers for use in small water systems

Creator:: Dzata, Francis K. A.
Resource Type:: Masters Thesis
Full Text:: h e e x p e r i m e n t p e r f o r m e d t o v e r i f y t h e e x t e n t o f c h

Topotactic Reduction and Reoxidation of Hexagonal RCu0.5Ti0.5O3 (R =Y, Eu-Lu) Phases

Creator:: Jiang, Peng, Berthelot, Romian, Li, Jun, Sleight, A. W., and Subramanian, M. A.
Abstract:: Hexagonal AMO₂ and AMO₃ phases have the same basic structure, and intermediate compositions for this structure have been prepared by topotactic oxidation of AMO₂ phases such as RCuO₂, where R is a trivalent rare earth cation. We now find that such intermediate phases can also be prepared by topotactic reduction...
Resource Type:: Article
Full Text:: Reduction and Reoxidation of Hexagonal RCu0.5Ti0.5O3 (R =Y, Eu-Lu) Phases Peng Jiang, Romian

Synthesis of substituted cyclooctatetraenide dianions ; Cycloheptadienyl complexes of the ḏ- and f̲-transistion elements ; Reactions of cyclohexanone with metal vapors

Creator:: Miller, Jeffrey Templeton
Abstract:: I. Lithium alkyl and aryl monosubstituted cyclooctatetraenide dianions (Li₂ C₈H₇-R; R = methyl, n- butyl, sec- butyl, tert- butyl, phenyl and benzyl) were synthesized by the reaction of the appropriate organolithium reagent with cyclooctatetraene in diethyl ether or tetrahydrofuran. The reaction occurred cleanly and with good yield of lithium monosubstituted...
Resource Type:: Dissertation
Full Text:: D UC1 4 02, Ram ethyl 11=n- butyl R=sec - butyl R=t-butyl R =phenyl R=benzyl Figure 1-1

Studies towards the total syntheses of (+)-phomactins A, D and G

Creator:: Schwartz, Keith D.
Abstract:: Studies towards the total synthesis of (+)-Phomactin A (1), D (6), and G (9), fungal metabolites with unique molecular architecture and pronounced biological activity, are described. These studies resulted in the synthesis of advanced intermediates 354 and 356, which contain all of the carbon atoms of 1, 6 and 9....
Resource Type:: Dissertation
Full Text:: DISSERTATION OF Keith D. Schwartz for the degree of Doctor of Philosophy in Chemistry presented

Enantioselective Total Syntheses of Quinolizidine Lycopodium Alkaloid Cermizine D and Cytotoxic Marine Macrolide Mandelalide A

Creator:: Veerasamy, Nagarathanam
Abstract:: The enantioselective total synthesis of quinolizidine-containing natural product cermizine D and formal syntheses of senepodine G and cermizine C has been achieved. These natural products are members of the lycopodium alkaloids, which have attracted significant attention due to their exciting biological activities and the diverse structural scaffolds. Key steps in...
Resource Type:: Dissertation
Full Text:: Physiol. 2004, 134, 339-351. (2) John Bostock, M. D.; Riley, F. R. S. H. T.; Esq, B. A. Pliny the Elder

ESCA studies of a brass surface subjected to gas-jet enhanced sputtering

Creator:: Govier, R. D.
Abstract:: The inert gas ion bombardment of solid surfaces has found many uses in the field of analytical chemistry. In one method of spectrochemical analysis, inert gas ion bombardment in a glow discharge is used to produce an atomic vapor, representative of the sample bulk, which is analyzed using atomic absorption...
Resource Type:: Masters Thesis
Full Text:: Enhanced Sputtering AN ABSTRACT OF THE THESIS OF Robert D. Govier for the degree of Master of Science in

The preparation of 2,4,7-trichloroimidazo [4,5-d] pyridazine and certain of its derivatives

Creator:: Laursen, Paul Herbert
Resource Type:: Dissertation
Full Text:: synthesis dich I orop rid azi ne. o + H2N--H R H N C C-H of imidazo[4,5-d]pyridazine from

Atmospheric trace element abundances associated with slash burning

Creator:: Ungerer, Carl Andre
Abstract:: The atmospheric trace element abundances associated with slash burning have been measured by instrumental neutron activation analysis (INAA). On site ground level samples were collected during the slash burning season using high volume samplers and a cascade impactor. In addition to the air samples, soil, wood and ashed wood samples...
Resource Type:: Masters Thesis
Full Text:: Co 46 Sc 182 Ta 75 Se 65 Zn 134 Cs 60 Co 152 Eu 12.401 H 13.800 H 15.000 H 1.096 D 1.479

Trace element abundances in automobile exhaust particulate

Creator:: Jones, Roger A.
Resource Type:: Masters Thesis
Full Text:: members of my committee, Dr. W. D. Loveland, Prof. J. G. Mingle, Dr. R. A. Schmitt, and Dr. B. I. Spinrad

Micro total analysis system for in-situ and autonomous spectrophotometric monitoring of iron in groundwater

Creator:: Koch, Corey R.
Abstract:: We have developed a compact micro total analysis system (μTAS) to serve as a platform for in-situ spectrophotometric water quality monitoring. Individual fluidic, optical, and electrical components were designed, developed, and characterized. These components were combined in both an integrated (single lithographic “chip-based” platform) and a modular manner. The microfluidic...
Resource Type:: Dissertation
Full Text:: . Chem. 1998, 194, 21-50. 4. Auroux, P. A.; Iossifidis, D.; Reyes, D. R.; Manz, A., Anal. Chem. 2002

Tandem intramolecular photocycloaddition-retro-Mannich fragmentation as a route to indole and oxindole

Creator:: Li, Yang
Abstract:: Irradiation of a tryptamine linked through its side-chain nitrogen to an alkylidene malonate residue results in an intramolecular [2 + 2] cycloaddition to the indole 2,3-double bond. The resultant cyclobutane undergoes spontaneous retro-Mannich fission to produce a spiro[indoline-3,3-pyrrolenine] with relative configuration defined by the orientation of substituents in the transient...
Resource Type:: Dissertation
Full Text:: , J. D.; Le Mahieu, R.; Mitra, R. B. J. Am. Chem. Soc. 1964, 86, 5570. 7. De Mayo, P

Cis-2,5-diaminobicyclo[2.2.2]octane : a novel C₂-symmetric scaffold for asymmetric catalysis

Creator:: Shaw, Subrata
Abstract:: This thesis describes the development of a new enantioselective synthetic method employing chiral cis-2,5-diaminobicyclo[2.2.2]octane-based organometallic catalysts. The significance of this new method to organic synthesis is illustrated with preparation of enantioenriched products that are transformed to important pharmaceutical agents. Chapter 1 provides a brief historical overview of asymmetric catalysis, especially...
Resource Type:: Dissertation
Full Text:: [2.2.2]octane: A Novel C2-Symmetric Scaffold for Asymmetric Catalysis Abstract approved: James D

Total synthesis of phorboxazole A

Creator:: Lee, Tae Hee
Abstract:: The total synthesis of a highly potent cytotoxic marine natural product, phorboxazole A, is described. Both a palladium(II)-mediated and a palladium(II)-catalyzed intramolecular alkoxycarbonylation were used as key steps for the preparation of the two cis-2,6-disubstituted tetrahydropyran rings (C22-C26 and C11-C15) of phorboxazole A. The synthesis used a convergent approach involving...
Resource Type:: Dissertation
Full Text:: phorboxazole A : (a) Forsyth, C. J.; Ahmed, F.; Cink, R. D.; Lee, C. S. J. Am. Chem. Soc. 1998, 120, 5597

Studies toward the total synthesis of (+)-providencin

Creator:: Jana, Somnath
Abstract:: Studies toward the total synthesis of (+)-providencin (1), a highly oxygenated cembranoid dipterpene with a unique bicyclo[12.2.0]hexadecane skeleton and pronounced biological activity, are described. These studies resulted in the synthesis of advanced intermediates 320 and 332 which contain all of the carbon atoms of 1. In a first generation approach...
Resource Type:: Dissertation
Full Text:: .; Baran, P.; Raptis, R. G. Org. Lett. 2003, 5, 2551. 2. Roethle, P. A.; Trauner, D. Nat. Prod. Rep. 2008

Studies towards the total synthesis of (-)-kendomycin

Creator:: Smits, Helmars
Abstract:: Studies towards the total synthesis of (−)-kendomycin (1), a bacterial metabolite with a unique molecular architecture and pronounced biological activity, are described. These studies resulted in the synthesis of advanced intermediate 208, containing all of the carbon atoms of 1. A Dötz annulation between alkyne 122 and novel chromium carbenoid...
Resource Type:: Dissertation
Full Text:: :_____________________________________________________ James D. White Studies towards the total synthesis of (−)-kendomycin (1), a bacterial

Polymeric submicron optical ion-selective sensors

Creator:: Bychkova, Valeriya
Abstract:: Ion-selective polymeric optical sensors – ion optodes – are a promising alternative to ion-selective electrodes and fluorescent dyes for analytical and biological applications, e.g. extra- and intracellular measurements. They are non-toxic, highly selective robust probes for ionic fluxes monitoring. A large-scale fabrication of ion optodes using a solvent displacement method...
Resource Type:: Dissertation
Full Text:: - Chemistry 1997, 38, 8-12. (4) Tan, W. H. S., Z.Y., Smith, S., Birnbaum, D., Kopelman, R. Science 1992

The kinetic and radiolytic aspects of control of the redox speciation of neptunium in solutions of nitric acid

Creator:: Precek, Martin
Abstract:: Neptunium, with its rich redox chemistry, has a special position in the chemistry of actinides. With a decades-long history of development of aqueous separation methods for used nuclear fuel (UNF), management of neptunium remains an unresolved issue because of its not clearly defined redox speciation. Neptunium is present in two,...
Resource Type:: Dissertation
Full Text:: to the past and present members of my doctoral committee at OSU: Dr. James D. Ingle, Dr. Walter D

Synthesis of a model of the spiroketal portion of avermectin B

Creator:: Warrier, Ulhas S.
Abstract:: Avermectin Bia is a member of a class of medicinally important natural products known for its potent antiparasitic activity and interesting structural features. In this thesis, synthesis of a model for the spiroketal portion of the avermectins is presented. Oxidation of (S)-2-methylbutanol, followed by a stereoselective chromium mediated reaction with...
Resource Type:: Masters Thesis
Full Text:: Bla Abstract approved: Redacted for privacy r Dr. James D. White Avermectin Bia is a member of a

[Lambda hyperon]-((R)-cysteinesulfenamido-N,S) bis (ethylenediamine) cobalt(III) complex : Characterization of the complex and kinetics and mechanism of formation and base-catalyzed decomposition

Creator:: Sanguanruang, Oravan
Resource Type:: Dissertation
Full Text:: [Lambda hyperon]-((R)-cysteinesulfenamido-N,S) bis

A stereochemically controlled approach to the morphine alkaloids: racemization of 8,9-benzo-4,5-dihydro-6,7-pyrido[4,3-d] oxanin-3(2H)-ones

Creator:: Runyan, Mark T.
Abstract:: A method for the control of absolute stereochemistry in morphine syntheses has been demonstrated by the resolution and efficient racemization of the advanced morphine precursor , 9-methoxy-3-methyl-5,6-dihydro-3H-benzofuro[3,2-e]isoquinoline- 7(7aH)-one, I. This was accomplished by the facile coversion of optically resolved I to its ring opened form, 5,6,7,8-tetrahydro-10-methoxy-3-methyl-7-oxo[1]benzoxonino[ 6,7-c]pyridinium tosylate, II, (Equation...
Resource Type:: Masters Thesis
Full Text:: 5 12.1 10.1 80 Scheme 5 113C H3C 30 16a 80% [a]r, + 48.3° 16b 79% [a]D - 48.3° 20 Et20

Examination of low-lying rovibrational states of D₃[subscript h] oblate top molecules using high resolution FTIR and coherent anti-Stokes Raman spectroscopies

Creator:: Kirkpatrick, Robynne
Abstract:: Interesting rovibrational characteristics of two D_(3h) oblate symmetric top molecules were studied. Hamiltonian models for the fine rovibrational level structure of [1.1.1]propellane (propellane) were obtained for many low-lying modes. Ground state parameters (GSP) that are not exclusively K^(2n) dependent were obtained. Initially, the GSP were used in conjunction with density...
Resource Type:: Dissertation
Full Text:: , Revision D.01, M. J. Frisch, G. W. Trucks, H. B. Schlegel, G E. Scuseria, M. A. Robb, J. R. Cheeseman, J

Total synthesis of (-)-7-epicylindrospermopsin

Creator:: Hansen, Joshua D.
Abstract:: The first asymmetric synthesis of (-)-7-epicylindrospermopsin via intramolecular nitrone cycloaddition is described. The synthesis utilized a convergent approach to prepare the cycloaddition precursor 176, which was assembled by condensation of hydroxylamine 175 with aldehyde 145. Hydroxylamine 175 was synthesized from ethylene glycol (166) in seven steps. Aldehyde 145 was completed...
Resource Type:: Dissertation
Full Text:: OF THE DISSERTATION OF Joshua D. Hansen for the degree of Doctor of Philosophy in Chemistry

Studies on the synthesis of the "northern" and "southern" segments of boromycin and aplasmomycin

Creator:: Kang, Myung Chol
Abstract:: The stereocontrolled synthesis of the southern lactone 17 of boromycin and of the northern segments of both boromycin and aplasmomycin are described. The syntheses begin with enantioselective epoxidation of 3-buten-2-ol (42) to provide the optically active 2(S),3(R) epoxy alcohol 43. The absolute configuration was confirmed by preparing 43 from (-)-2,3-dihydroxybutyric...
Resource Type:: Dissertation
Full Text:: I ego ne D -Ma nnose 20 A.v. + 21 /VA 11-Bu i -Pr 7 N Si 22".". R=TBDM S 23 24AA" CH3 11

Synthesis of metabolites from the ascomycetes : I. The synthesis and absolute configuration of leptosphaerin : II. Approaches to the synthesis of byssochlamic acid

Creator:: Pallenberg, Alexander J.
Abstract:: Part I. The total synthesis of (+)-leptosphaerin (2), a metabolite of the marine Ascomycete Leptosphaeria Oraemaris (Linder) was achieved, unambiguously establishing both the relative and absolute stereochemistry of this natural product. This synthesis also resolved the long-standing question of which of the isomeric structures 1 or 2 correctly represents the...
Resource Type:: Dissertation
Full Text:: - 190.5°C): [a]r, +400 (c 0.2, H2O); 1F1 NMR (400MHz, acetone-d6) S 7.46 (1H, d, J=1.95), 5.06 (1H, dd, J

Approaches to the synthesis of methymycin

Creator:: Raghavan, Palaykotai Rajagopalan
Abstract:: Several approaches to the synthesis of methymycin were investigated. Segment A (39), containing functionality corresponding to C-9, 10, and 11 of methynolide was made in six steps from propionaldehyde in an overall yield of 37%. Oxidation of 34 with silver nitrate gave 35 which, upon hydroxylation with hydrogen peroxide, gave...
Resource Type:: Dissertation
Full Text:: approved: Dr. James D. White Several approaches to the synthesis of methymycin were investigated

Target fragmentation in the interaction of relativistic heavy ions and protons with ¹⁸¹Ta

Creator:: Oertel, Christopher Paul
Abstract:: The production cross sections for a number of target fragments formed by the reactions of 42- and 21- GeV²⁰ Ne and 28 GeV p with ¹⁸¹Ta have been measured. The target fragment radioactivities were measured by off-line gamma-ray spectroscopy. Details of the measurement as well as the calculation of the...
Resource Type:: Masters Thesis
Full Text:: Walter D. Loveland The production cross sections for a number of target fragments formed by the

Absolute stereochemistry and total synthesis of botryococcene

Creator:: Reddy, Guvvala Nagabhushana
Abstract:: Studies were carried out to determine the absolute stereochemistry of botryococcene (1). The natural product was degraded to two sets of 'y- and 8- valerolactones. All enantiomeric variations of these lactones were synthesized in optically pure form starting from (S)- and (R)-methyloxiranes. 1H NMR correlation of natural and synthetic materials...
Resource Type:: Dissertation
Full Text:: Botryococcene Abstract approved: Pedacted for Privacy Li James D. White Studies were carried out to determine

Studying fusion reactions for effect of PCN on heavy nucleus formation and for nuclear structure effects

Creator:: Naik, Radhika
Abstract:: The fusion reaction ²⁰⁸Pb (⁵⁰Ti, xn) ²⁵⁸⁻x Rf (x = 1-3) was studied to determine PCN (probability that the mononucleus system evolves to form a compound nucleus inside the fission saddle point) and to establish the value of Wsur (survival probability) for the given reaction experimentally. The fission excitation function...
Resource Type:: Dissertation
Full Text:: Walter D. Loveland The fusion reaction 208Pb (50Ti, xn) 258-xRf (x = 1-3) was studied to determine

Synthesis of two subunits of avermectin B1a

Creator:: Dantanarayana, Anura Pathmasiri
Abstract:: Avermectins are a group of potent anthelmintic agents produced by Streptomyces avermitilis. They are active at extremely low dosages and are now in commercial use. In this study, the synthesis of two segments of avermectin B[subscript 1a] are described. The synthesis of the hexahydrobenzofuran subunit (segment A) began with the...
Resource Type:: Dissertation
Full Text:: approved: Redacted for privacy (it James D. White Avermectins are a group of potent anthelmintic agents

Approaches to the synthesis of the macrolactone pyrrolizidine alkaloids (-)-integerrimine and (+)-usaramine

Creator:: Jayasinghe, Lalith Ratnasiri
Abstract:: A formal total synthesis of the macrolactone pyrolizidine alkaloid (-)-integerrimine (2), from R-(+)-citronellal (93) is described. Aldehyde 93 was converted to exo methylene derivative 94 which was reduced to allylic alcohol 95. The epoxides 96 and 98, obtained in a ratio of 3:1 respectively by Sharp less epoxidation of 95...
Resource Type:: Dissertation
Full Text:: . Redacted for privacy Abstract approved: James D. White A formal total synthesis of the macrolactone

Synthetic studies on marine natural products : Part 1. Synthesis of the sesquiterpenoid dihydropallescensin D via manganese(III)- mediated carbocyclization. Part 2. Approaches toward the synthesis of prianosin and discorhabdin alkaloids

Creator:: Yager, Kraig M.
Resource Type:: Dissertation
Full Text:: . Synthesis of the sesquiterpenoid dihydropallescensin D via manganese(III)- mediated carbocyclization. Part 2

The urea denaturation of bovine serum albumin, polyglycyl bovine serum albumin and poly-L-phenylalanyl bovine serum albumin

Creator:: Chung, Po-luen
Abstract:: A comparative study was made on the effect of urea denaturation of bovine serum albumin (BSA), polyglycyl BSA and poly-L-phenylalanyl BSA. The denaturation process was followed by ultraviolet spectrophotometry and optical rotation. A blue shift in the absorption maximum at 278 mμ was observed in urea denatured proteins, In 7M...
Resource Type:: Masters Thesis
Full Text:: Robert R. Becker whose innumerable suggestions were of invaluable aid to me during the course of my

Design of a chemiluminescence photometer and its application to trace chromium (III) analysis

Creator:: Hoyt, Steven D.
Abstract:: The design and construction of a chemiluminescence photometer is described. The design is based on a discrete sample system which has a number of advantages over the previously described flow cell system and centrifugal analyzer. The advantages include simple and inexpensive equipment, small sample size, versatile electronic readout system, and...
Resource Type:: Masters Thesis
Full Text:: major Redacted for Privacy Chairman of the D partment of Cheiiitry Redacted for Privacy Dean of

The determination of gasoline and alkyl benzenes in aqueous solution and the development of a remote reaction chamber for fiber optic remote sensing

Creator:: Waddle, Robert D.
Abstract:: The development and optimization of a single-phase derivatization technique for small ring aromatics in water are presented. Also described are the design, optimization and application of a remote reaction chamber for fiber optic sensing. Aqueous solutions of the major aromatic compounds in gasoline are derivatized to o-nitrosophenol-Cu complexes with a...
Resource Type:: Masters Thesis
Full Text:: 8.5 52.4 C 37.6 3.4 59.0 D 43.7 7.8 48.5 14 aMiller, R. L., J. Chromatogr., 264, (1983) 19-32 15

Approaches toward synthesis of the mycosporins

Creator:: Cammack, Janice H.
Abstract:: The mycosporins, formerly called P310's are secondary metabolites of fungi closely associated with fungal reproductive processes that require light. The structurally related iminomycosporins are found in marine plants and animals and may also have functions related to light. In this study, approaches toward the asymmetric synthesis of the mycosporins are...
Resource Type:: Dissertation
Full Text:: . James D. White Abstract approved: The mycosporins, formerly called P310's are secondary metabolites

Studies toward the total synthesis of sanglifehrin A

Creator:: Suttisintong, Khomson
Abstract:: Studies toward synthesis of subunits of sanglifehrin A, an immunosuppressant featuring a highly substituted [5,5]-spirolactam moiety as well as a 22-membered macrocycle are described. The macrolactone contains a peptidic backbone characterized by an unusual [beta]-substituted (S)-piperazic acid and (S)-m-hydroxyphenylalanine units. These studies resulted in the synthesis of advanced intermediate 358...
Resource Type:: Dissertation
Full Text:: :______________________________________________________ James D. White Studies

Proton-neutron-hole states in antimony isotopes populated in the beta decay of ¹²⁸SN and ¹³⁰SN

Creator:: Nunnelley, Lewis Lee
Abstract:: ¹³⁰ Sn and ¹²⁸Sn were separated from mixed fission products. The decay of these isotopes were studied with Ge(Li), LEPS, and plastic scintillator detector systems in single and two parameter coincidence modes. The decay scheme constructed for ¹²⁸Sn decay has levels at 0.0 (5+), 45.7 (4+), 77.8 (3+), 152.9 (2+),...
Resource Type:: Dissertation
Full Text:: -polarization was used to try to explain the hindrance in the 6 decay of a d3/2 neutron to a d 5/2 proton

Synthesis of epothilones and epothilone analogues

Creator:: Sundermann, Kurt F.
Abstract:: A convergent synthesis of epothilone B that generates all seven of its asymmetric centers in a completely stereoselective fashion has been completed. Key reactions include an anti-Felkin aldol condensation to set the C6 and C7 stereochemistry, a directed α-hydroxylation to install the C15 (S)-hydroxyl substituent, and a Wittig condensation to...
Resource Type:: Dissertation
Full Text:: ) Epothilone C (3) Figure 1. The Original Epothilones. Epothilone D (4) R1 S Epothilone E (5), R1 = OH; R

Fluoroboranes : I. Preparation and properties of trifluoromethyldi-n-butylborane : II. A study of doboron tetrafluoride

Creator:: Self, James Maurice
Abstract:: A large-scale preparative method for potassium di-n-butylborate in triethylamine solvent has been developed. The reaction of potassium di-n-butylborate I with trifluoromethyl iodide has been shown to yield trifluoromethyl di-n-butylborane and other products. Reaction of this substance with boron trifluoride gave trifluoromethyl boron difluoride. Reactions of diboron tetrafluoride, boron tribromide, and...
Resource Type:: Dissertation
Full Text:: Self for the Ph. D. in Inorganic Chemistry (Name) (Degree) (Major) Date thesis is presented , ,7//,9

Synthetic transformations of shikimic acid

Creator:: White, Edward D., III
Abstract:: Four strategies which involve synthetic elaboration of the shikimate nucleus are discussed. Methyl shikimate was differentially protected as the 3,4-0-cyclopentylidene ketal and as the 5- 0- tert- butyldiphenylsilyl ether. The methyl ester was then reduced with diisobutylaluminum hydride and the resulting allylic alcohol was oxidized to aldehyde 47 with pyridinium...
Resource Type:: Masters Thesis
Full Text:: OF THE THESIS OF Edward D. White III for the degree of Master of Science in Chemistry presented on

An approach to the morphine alkaloids : synthesis of 9-methoxy-3-methyl-2,3,4,4a,5,6-hexahydro-1H-benzofuro[3,2-e]isoquinoline-7(7aH)-ones

Creator:: Weller, Doreen L.
Resource Type:: Dissertation
Full Text:: -hexahydro-1H-benzofuro[3,2-e]- isoquinoline-7(7aH)-ones Abstract approved: Redacted for privacy Dwight D

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