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Filtering by: Creator Giesen, Thomas William Remove constraint Creator: Giesen, Thomas William Academic Affiliation Chemistry Remove constraint Academic Affiliation: Chemistry

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  • Formation of alkyl-and dialkylcarbenes. The 3-cyclohexenyl carbinyl carbene system

    Creator:
    Crouse, Dale McClish
    Abstract:
    The 3-cyclohexenyl carbinyl carbene species was formed by the thermal decomposition of the p-toluenesulfonylhydrazone sodium salt and by oxidation of the hydrazone. Several oxidizing agents were studied. The products were investigated under aprotic and protic conditions and at various temperatures. The diazocompound was formed as an intermediate and found to...
    Resource Type:
    Masters Thesis
    Full Text:
    Gwendolyn Hansen ACKNOWLEDGEMENTS I wish to express my appreciation to Dr. F. Thomas Bond for his

  • Reactions of organoboranes

    Creator:
    Thompson, Thomas Myron
    Abstract:
    An examination was made of some reactions involving a transfer of carbon from boron to carbon. In the case of the reaction of a C[subscript n] alkylorganoborane with dichlorocarbene the intermediate was a C[subscript n]₊₁ chloroalkylorganoborane. Oxidation of this intermediate yielded an homologous acid (33%) and the usual alcohol (66%)....
    Resource Type:
    Masters Thesis
    Full Text:
    Thomas Myron Thompson for the M. S. in Chemistry (Organic) (Name) (Degree) (Major) Date thesis is

  • Steroid-dihalocarbene reactions

    Creator:
    Damewood, John Roderick
    Abstract:
    Dihalocarbenes have been generated by thermal decomposition of sodium trichloroacetate and tribromomethylphenylmercury, and give mono dihalocyclopropyl adducts with steroid dienes. Such compounds offer an easy starting point for the synthesis of unusual derivatives of potential biological interest. Under the same conditions, however, addition to non-conjugated double bonds does not take...
    Resource Type:
    Masters Thesis
    Full Text:
    Dr. F. Thomas Bond for his guidance and assistance in the preparation of this thesis. TABLE OF

  • Dihalocarbene reactions with steroid olefins

    Creator:
    Cornelia, Richard Hartman
    Abstract:
    Dihalocarbenes have been generated mainly by thermal decomposition of sodium trihaloacetate and phenyl (trihalomethyl)mercury, and give gem-dihalocyclopropyl adducts with various steroid olefins. A new procedure involving the use of sealed tubes makes possible the addition of dihalocarbenes to sterically hindered olefins. In this manner, 7-cholestenyl benzoate when treated with PhHgCC1₃...
    Resource Type:
    Dissertation
    Full Text:
    . Thomas Bond for his critical reading of the manuscript. TABLE OF CONTENTS INTRODUCTION 1

  • Some synthetic efforts in small ring chemistry

    Creator:
    Lam, Luke Kwok Tung
    Abstract:
    Cyclopropylcyclobutene was prepared via the intermediate dicyclopropylcarbinyl carbene which was generated by the thermal decomposition of the sodium salt of dicyclopropylketone p-toluenesulfonylhydrazone. The successive thermal isomerization of cyclopropylcyclobutene to 2-cyclopropyl-1, 3-butadiene and to vinylcyclopentene was studied. Kinetic data were obtained for the cyclopropylcyclobutene to 2-cyclopropyl-1, 3-butadiene isomerization in the gas...
    Resource Type:
    Masters Thesis
    Full Text:
    . Thomas Bond Cyclopropylcyclobutene was prepared via the intermediate dicyclopropylcarbinyl carbene

  • Steroid dialkylcarbene reactions

    Creator:
    Dixon, Dale David
    Abstract:
    Steroid carbenes have been investigated as synthetic intermediates. Basic decomposition of 4-en-3-one tosylhydrazones (and other A-ring systems) gives varying amounts of 2, 4-dienes, and solvent derived products with diglyme, heptane, tetrachloroethylene, carbon tetrachloride, benzene and cyclohexene. A method for separating complex product mixtures was developed and a study of the...
    Resource Type:
    Dissertation
    Full Text:
    express my appreciation to Dr. F. Thomas Bond for his instruction, encouragement, and scientific

  • The synthesis and chemistry of strained bicyclic systems

    Creator:
    Scerbo, Louis
    Abstract:
    A facile route to bicyclo(2.1.1)hexanes was developed involving the intramolecular photocyclization of 1, 5-hexadien-3-one to bicyclo(2.1.1)hexan-2-one. A study of the chemistry of bicyclo-(2.1.1)hexan-2-one was undertaken. Deuterium exchange and borohydride reduction demonstrated the strain present in the ketone. Further evidence was obtained from the failure to introduce substituents alpha to the...
    Resource Type:
    Dissertation
    Full Text:
    Abstract approved Dr. F. Thomas Bond A facile route to bicyclo(2. 1. 1)hexanes was developed involving

  • Chemistry of cyclobutane compounds

    Creator:
    Musa, Willie Edsel
    Abstract:
    Examination of a proposed reaction scheme to prepare bicyclo-(2.2.0)hexan-1-ol produced the first known condensation of an enamine with its carbonyl precursor. Hydrolysis of the resulting dienamine gave an unusual conjugated cyclobutenone in which the double bond is exocyclic. Characterization and reactions of the cyclobutenone were successfully carried out.
    Resource Type:
    Masters Thesis
    Full Text:
    (ltr5 ACKNOWLEDGEMENT The author wishes to express his appreciation to Dr. F.. Thomas Bond for his

  • Steroid organoborane reactions

    Creator:
    Byall, Elliott Bruce
    Abstract:
    Steroid organoboranes have been found to be useful synthetic intermediates. Attempted pyrolyses, based on simple trialkylborane cyclizations, have not yielded C-19 or C-18 functionalized steroids, but have produced isomerized systems not otherwise available. Thus, hydroboration of cholesterol followed by pyrolysis at 215° gives 31% of 2-cholestene-6α-ol and 49% of a...
    Resource Type:
    Dissertation
    Full Text:
    . Thomas Bond Steroid organoboranes have been found to be useful synthetic intermediates. Attempted

  • Some features influencing the valence isomerism of cis-dienones to α-pyrans

    Creator:
    Gosink, Thomas A. (Thomas Anthony)
    Resource Type:
    Dissertation
    Full Text:
    AN ABSTRACT OF THE THESIS OF THOMAS ANTHONY GOSINK for the