Index Catalog // ScholarsArchive@OSU

Purification of cyclotron-produced 89Zr for its use in diagnostic radiopharmaceutical labeling

Creator:: Knaus, Clinton W.
Abstract:: Production of 89Zr serves as a crucial preliminary step for exploring Zr-chelates, determining their stability constants, and advancing radiolabeling methodologies for monoclonal antibody based theranostics. 89Zr is typically produced by the irradiation of natural yttrium targets, a process extensively documented in scientific literature. Two primary methods are employed: the 89Y(p,n)89Zr...
Resource Type:: Capstone Project
Full Text:: .................................................................................................. 82 3.5.2. Radionuclidic Purity

Optimizing the Membrane Architecture and Interrogating the Stability of Hybrid Lipid-coated Gold Nanoparticles for Biological Studies and Applications

Creator:: Kmetz-Gonzalez, Gemma
Abstract:: Nanoparticles are a hugely diverse category of material that have a wide variety of biomedical applications, and developing tools for biological research with high cellular uptake is critical to their effective application. However, rarely is attention paid to the exact mechanism by which this is occurring, with most studies focusing...
Resource Type:: Capstone Project
Full Text:: hydrodynamic diameter (HDD) and zeta-potential by dynamic light scattering. No significant changes in optical

Comprehensive Analysis of The Brain Metabolome Using Mass Spectrometry in Conjunction with Data Analysis Techniques

Creator:: Khorani, Mona
Abstract:: Metabolomics has recently gained momentum in biomolecule research and complements the genomics and proteomics research space. Metabolomics strives to detect, identify, and quantify all metabolites present in biological samples. In particular, biomolecular analysis using ultra-performance liquid chromatography combined with mass spectrometry (UPLC-MS) has become increasingly important for metabolomic analyses. Similarly,...
Resource Type:: Dissertation
Full Text:: ......................................................................................................................... 15 2.2 Internal Standards

Novel Charge Carriers for Aqueous Electrochemical Energy Storage

Creator:: Sandstrom, Sean K.
Abstract:: The continued long-term use of fossil fuels as a primary energy source has resulted in dramatic increases in greenhouse gas emissions and the associated concerns of climate change and environmental pollution. A key strategy to circumvent these issues is a global shift away from fossil fuels toward renewable energy sources....
Resource Type:: Dissertation
Full Text:: result in increased internal impedance and mechanical disintegration of the electrode materials.28

Electrochemical Reactions in Aqueous Batteries with Anionic Charge Carriers

Creator:: Gallagher, Trenton C.
Abstract:: In this dissertation, the primary objective is to discover more sustainable electrode materials and study new reaction mechanisms using aqueous electrolytes. The first study conducted reveals a reversible conversion reaction from copper to Cu2CO3(OH)2. The reaction mechanism uses OH- and CO32- as charge carriers at the cathode. The results open...
Resource Type:: Dissertation
Full Text:: .............................................................................................82 LIST OF FIGURES (Continued

Laser patterned porous-media microfluidic analytical devices : fabrication methods and applications in bioassays

Creator:: Sumantakul, Saichon
Abstract:: The concept of reducing laboratory operations into microfluidic devices has been an attractive area of research for several decades. Due to several advantages of porous-media microfluidic devices including low mass, portability, power-free fluid transport, and the ability to store dried reagents in the porous structures, these devices show great promise...
Resource Type:: Dissertation
Full Text:: training. I have no doubt that the hard and soft skills I have developed during my time at OSU will

New Approaches for Quantifying Target and Estimating Suspect PFAS in Complex Media

Creator:: Cao, Dunping
Abstract:: Per- and polyfluoroalkyl substances (PFAS) are a group of anthropogenic compounds that are used ubiquitously in different industrial fields. However, concerns regarding the potential health impacts of PFAS, including perfluoroalkyl carboxylic acids (PFCAs) and perfluoroalkyl sulfonates (PFSAs), has raised stakeholder interest regarding continued use of PFAS. Analytical methods for PFAS...
Resource Type:: Dissertation
Full Text:: laboratory fish diet [36, 37]. However, to date, there is no report on the determination of PFAS

A Pyrone Diels–Alder Approach to Substituted Indoles and Carbazoles and the Synthesis of New Ropinirole Analogues

Creator:: Points, Gary L., III
Abstract:: Aromatic heterocycles are core structural motifs in natural products, pharmaceuticals and biological polymers. Indoles, in particular, represent a significant subclass of aromatic heterocycles, both in terms of sheer numbers, but also in biological and pharmaceutical relevance. As such, new methodologies for the synthesis of indoles represent an important and continually...
Resource Type:: Dissertation
Full Text:: …....……………...……………...82

Low-Dose X-Ray Radiation Effects On the Proteomic Profiles of Hippocampus, Cortex, and Cerebellum of Contextual Fear Conditioning and Novel Object Recognition Trained Mice

Creator:: Koluda, Rony
Abstract:: Radiation exposure to the brain can occur from a variety of events, including space missions, nuclear accidents, and clinical treatments. The effects of high dose radiation are well studied, but those of lower dosage are more elusive. Decline of memory and cognition is observed in patients exposed to low dose...
Resource Type:: Masters Thesis
Full Text:: in contextual fear memory, while no effect is seen on novel object recognition. Mass spectrometric

Computational Investigation into the Mechanisms and Origins of Selectivity in Selected Organic and Organometallic Chemical Processes

Creator:: Harper, Jordan L.
Abstract:: Put generally, the work I have conducted in my time at Oregon State University has been to answer two questions. The first of these is “Why do I get this particular product from this particular chemical reaction?” and the second is “How do the reagents in this chemical reaction lead...
Resource Type:: Dissertation
Full Text:: IV, VI, and VIII….. 82 5.10. Experimentally observed kinetic isotope effects………………………………. 83

ScholarsArchive@OSU

Purification of cyclotron-produced 89Zr for its use in diagnostic radiopharmaceutical labeling

Optimizing the Membrane Architecture and Interrogating the Stability of Hybrid Lipid-coated Gold Nanoparticles for Biological Studies and Applications

Comprehensive Analysis of The Brain Metabolome Using Mass Spectrometry in Conjunction with Data Analysis Techniques

Novel Charge Carriers for Aqueous Electrochemical Energy Storage

Electrochemical Reactions in Aqueous Batteries with Anionic Charge Carriers

Laser patterned porous-media microfluidic analytical devices : fabrication methods and applications in bioassays

New Approaches for Quantifying Target and Estimating Suspect PFAS in Complex Media

A Pyrone Diels–Alder Approach to Substituted Indoles and Carbazoles and the Synthesis of New Ropinirole Analogues

Low-Dose X-Ray Radiation Effects On the Proteomic Profiles of Hippocampus, Cortex, and Cerebellum of Contextual Fear Conditioning and Novel Object Recognition Trained Mice

Computational Investigation into the Mechanisms and Origins of Selectivity in Selected Organic and Organometallic Chemical Processes

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