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Filtering by: Committee Member Ishmael, Jane Remove constraint Committee Member: Ishmael, Jane Academic Affiliation Chemistry Remove constraint Academic Affiliation: Chemistry

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  • Insights into Cytostatic and Cytotoxic Properties of the Natural Product Mensacarcin

    Creator:
    Kaweesa, Elizabeth Namagoba
    Abstract:
    Mensacarcin is a stereogenic complex polyketide with potent anti-tumor activity produced by a soil-dwelling Streptomyces bottropensis. The US National Cancer Institute (NCI) 60 human tumor cell line anticancer drug screen (NCI-60) reveals mensacarcin’s cytostatic properties in almost all tested cell lines and distinct cytotoxic properties specifically in eight melanoma cell...
    Resource Type:
    Masters Thesis
    Full Text:
    Blakemore, Dr. Jane Ishmael, Dr. Kerry McPhail, Dr. Siva Kolluri and Dr. Taifo Mahmud for their insight