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Filtering by: Creator Loprinzi, Paul D. Remove constraint Creator: Loprinzi, Paul D. Academic Affiliation Chemistry Remove constraint Academic Affiliation: Chemistry

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  • Total synthesis of phorboxazole A

    Creator:
    Lee, Tae Hee
    Abstract:
    The total synthesis of a highly potent cytotoxic marine natural product, phorboxazole A, is described. Both a palladium(II)-mediated and a palladium(II)-catalyzed intramolecular alkoxycarbonylation were used as key steps for the preparation of the two cis-2,6-disubstituted tetrahydropyran rings (C22-C26 and C11-C15) of phorboxazole A. The synthesis used a convergent approach involving...
    Resource Type:
    Dissertation
    Full Text:
    : James D. White The total synthesis of a highly potent cytotoxic marine natural product

  • Studies toward the synthesis of halichlorine and pinnaic acid

    Creator:
    Korf, Eric A.
    Abstract:
    Three approaches toward the core of halichlorine and pinnaic acid are described. The first approach entails a racemic transannular nitrone-olefin [3+2] cycloaddition from nitrone 238. Construction of the nitrone 238 began with aldehyde 241. Another key feature in this route involved a ring-closing metathesis for the formation of a 14-membered...
    Resource Type:
    Dissertation
    Full Text:
    approved: James D. White Three approaches toward the core of halichlorine and

  • Studies towards the total synthesis of (-)-kendomycin

    Creator:
    Smits, Helmars
    Abstract:
    Studies towards the total synthesis of (−)-kendomycin (1), a bacterial metabolite with a unique molecular architecture and pronounced biological activity, are described. These studies resulted in the synthesis of advanced intermediate 208, containing all of the carbon atoms of 1. A Dötz annulation between alkyne 122 and novel chromium carbenoid...
    Resource Type:
    Dissertation
    Full Text:
    :_____________________________________________________ James D. White Studies towards the total synthesis of (−)-kendomycin (1), a bacterial

  • Studies toward the total synthesis of alkaloids : nagelamide A and D, agelastatin D, dragmacidin A-C, salacin and almazoles

    Creator:
    Tonsiengsom, Sorasaree
    Abstract:
    Studies toward the total syntheses of highly potent cytotoxic alkaloids including the bromopyrrole alkaloids and indole alkaloids were conducted and are described. Studies carried out in the course of this dissertation consist of five total syntheses of natural products that include bromopyrrole alkaloids nagelamide A, D and agelastatin D as...
    Resource Type:
    Dissertation
    Full Text:
    : STUDIES TOWARD THE TOTAL SYNTHESIS OF ALKALOIDS: NAGELAMIDE A AND D, AGELASTATIN D, DRAGMACIDIN A-C

  • Tracking semi-volatile organic pollutants in remote lake systems

    Creator:
    Usenko, Sascha
    Abstract:
    SOCs volatility and persistence properties cause many SOCs to become ubiquitous in the environment as well as accumulate in areas with lower temperatures such as polar or orographic regions. Many anthropogenic SOCs pose a serious risk to human and ecosystem health because of their persistent, bioaccumulative, and toxic properties in...
    Resource Type:
    Dissertation
    Full Text:
    ………………………………………….. 149 APPENDIX C. Lake Water SOC Database ………………………………… 164 APPENDIX D. Sediment SOC Database

  • Semi-volatile fluorinated organic compounds in Asian and Pacific Northwestern U.S. air masses

    Creator:
    Piekarz, Arkadiusz M.
    Abstract:
    Current studies suggest that perfluorinated organic compounds, such as fluorotelomer alcohols (FtOHs) in the troposphere, may be precursors of perfluorocarboxylic acids and perfluorosulfonates in remote regions. Fluorinated organic compounds were investigated in archived extracts collected from remote locations in Okinawa, Japan (HSO) and Mount Bachelor, Oregon (MBO) during the springs...
    Resource Type:
    Masters Thesis
    Full Text:
    ............................................................................................................ 12 Page ..... 65 ..... 66 NS ..... 67 D ..... 68 ..... 69 CHAPTER 1 INTRODUCTION

  • Determination of fluorochemicals in waste-dominated aqueous systems

    Creator:
    Huset, Carin A.
    Abstract:
    While fluorochemicals have been detected all over the world and in wastewater treatment plants, the effect of wastewater effluent on the receiving waters has not been evaluated. In the first study, the mass flow of fluorochemicals emanating from wastewater treatment plants along the Glatt River in Switzerland was evaluated. The...
    Resource Type:
    Dissertation
    Full Text:
    year opened for Site D……………………..….... 122 LIST OF APPENDIX FIGURES (Continued

  • Biological oxidation of sorbitol

    Creator:
    Cummins, Joseph Thomas
    Abstract:
    The oxidation of sorbitol by soluble extracts of A. suboxydans proceeds by two pathways depending upon which pyridine nucleotide is present. In the presence of TPN, sorbose is formed. In the presence of DPN fructose is produced. Both products of the oxidation of sorbitol have been identified by paper chromatography,...
    Resource Type:
    Dissertation
    Full Text:
    glycols are attacked by this organism. D-2,3-Butane- diol and D-3,4-hexanediol are oxidized to the

  • Solution deposition and characterization of the thin film inorganic materials

    Creator:
    Özmen, Bahar
    Abstract:
    The general emphasis of this work has been synthesis, characterization, and applications of n- and p-type inorganic oxide thin films that are deposited from solutions. In particular, a study of n-type transparent semiconductor films of tin (IV) oxide and zinc-doped tin (IV) oxide has been performed by spin coating. Solution...
    Resource Type:
    Masters Thesis
    Full Text:
    AFM measurements, to Paul Newhouse for his resistivity measurements on my films and to Dr. Wager’s

  • From electrophoresis to dielectrophoresis: designing, fabricating, and evaluating an electroformed ratchet type microfluidic dielectrophoresis device

    Creator:
    Gonzalez, Carlos F.
    Abstract:
    Dielectrophoresis (DEP) is a separation method in which a non-uniform electric field is used to induce a dipole moment in a suspended particle. If the polarization of the particle is greater than that of the suspending medium, the particle will move towards the region of higher field strength (positive DEP);...
    Resource Type:
    Dissertation
    Full Text:
    to my committee members: Dr. Nathan Ballou, Dr. James Ingle, Dr. Brian Paul, Dr. William Warnes