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Filtering by: Creator Meier, Emily K. Remove constraint Creator: Meier, Emily K. Academic Affiliation Chemistry Remove constraint Academic Affiliation: Chemistry

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  • Carbene rearrangements : intramolecular interaction of a triple bond with a carbene center

    Creator:
    Dan̄ino, José C.
    Abstract:
    The tosylhydrazones of 2-heptanone, 4,4-dimethy1-2- heptanone, 6-heptyn-2-one and 4,4-dimethy1-6-heptyn-2- one were synthesized and decomposed under a variety of reaction conditions: dry lithium and sodium salt pyrolyses, sodium methoxide thermolyses in diglyme and photolyses of the lithium salt in tetrahydrofuran. The saturated analogues 2-heptanone tosylhydrazone and its 4,4-dimethyl isomer afforded the...
    Resource Type:
    Dissertation
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    ACKNOWLEDGEMENTS It is difficult to express with words the gratitude the author feels towards Professor Peter K

  • Displacement-based fluorescent microRNA biosensors : design principles and analytical metrics

    Creator:
    Larkey, Nicholas E.
    Abstract:
    One post-transcriptional mechanism that regulates the progression of cancer and other diseases involves small 22-23 nucleotide sequences called microRNA (miR). Early detection of small changes in concentration of these biomarkers holds potential to diagnose diseases at their earliest stages. Use of current nucleic-acid based biosensors, like molecular beacons, for in...
    Resource Type:
    Dissertation
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    also thank the other members of my graduate committee: Dr. Vincent Remcho, Dr. Ryan Mehl, Dr. Emily

  • Investigation of the structural influence on the properties of functional inorganic oxides

    Creator:
    Laurita-Plankis, Geneva
    Abstract:
    While properties are extremely important from an application point of view, it is crucial to have a detailed understanding of the underlying structural influence. Once a concrete correlation between the structure and the observed property is established, rational design of novel materials with optimized properties can be realized. These optimized...
    Resource Type:
    Dissertation
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    materials for electronic and energy applications. A series of pyrochlores Ag1-nxMnxSbO3 (M = Na+, K+, Tl

  • Galvanostatic control of ion selective electrodes with the solvent polymeric membrane

    Creator:
    Perera, Hasini R.
    Abstract:
    Detection technique that proposed utilizing electrochemically controlled, reversible ion extraction into polymeric membrane in an alternating galvanostatic/ potentiostatic mode was introduced. This method is studied in detail to comprehend the advantages of the novel sensor (pulstrode) compared to the potentiometric ion selective electrode (ISE), studies included possible applications and limitations....
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    Dissertation
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    error. Further studies with K + , Ag + and Ca 2+ selective electrodes reveal that pulstrodes yield

  • The Role of Materials Chemistry in Designing Advanced Color Inorganic Pigments

    Creator:
    Medina, Elena A.
    Abstract:
    The results of the research presented in this work are related to synthesis and investigations of novel color inorganic pigments having various structures and shades. Inorganic pigments play a major role in contemporary life. They are used in paints, rubber, plastic, cosmetics etc. Searching for new, stable, environmentally benign and...
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    Dissertation
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    show paramagnetic behavior in the measured temperature region (5–300 K). All synthesized

  • CoLocalized Excitation Emission Resolution : A CLEER approach for multicolor fluorescence analysis

    Creator:
    Almlie, C. Kyle
    Abstract:
    Fluorescence has proven to be a robust and powerful method of analysis in numerous fields: forensics, pharmaceutics, geology, food science, and environmental sciences have all developed a large collection of fluorescence instruments and methods to overcome application-specific challenges. Biological applications saw the same development of a fluorescence toolkit with methods...
    Resource Type:
    Dissertation
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    ). Furthermore, the comparison of theoretical thermodynamic (∆G) and equilibrium (K) values to experimental

  • Effects of small molecule ligands on the conformational dynamics of the Farnesoid X Receptor ligand binding domain (FXR-LBD)

    Creator:
    Yang, Liping
    Abstract:
    The Farnesoid X Receptor (FXR) is a member of the nuclear receptor superfamily of transcription factors that plays a key role in the regulation of bile acids, lipid and glucose metabolisms. The regulative function of FXR is governed by conformational changes of the ligand binding domain (LBD) upon ligand binding....
    Resource Type:
    Dissertation

  • Venturing Beyond Crystallinity and Into Amorphous Space : A Na-ion Battery Perspective

    Creator:
    Bommier, Clement
    Abstract:
    As scientists, we have an affinity for order: repeating crystal structures, Euclidean space, continuous functions… Even concepts such as defects are discussed in the context of distracting from order. Things are most logical and best described in straightforward, taxonomical fashion. But what happens when the very application desired is dependent...
    Resource Type:
    Dissertation
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    batteries (LIBs) or K-ion batteries (KIBs), use graphite as an anode material due to its ease of forming

  • Polymeric submicron optical ion-selective sensors

    Creator:
    Bychkova, Valeriya
    Abstract:
    Ion-selective polymeric optical sensors – ion optodes – are a promising alternative to ion-selective electrodes and fluorescent dyes for analytical and biological applications, e.g. extra- and intracellular measurements. They are non-toxic, highly selective robust probes for ionic fluxes monitoring. A large-scale fabrication of ion optodes using a solvent displacement method...
    Resource Type:
    Dissertation
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    developed recently. They can reliably measure the most relevant cations (H + , Na + , K + , Ca 2+ , Mg

  • Polycyclic Aromatic Hydrocarbons in Atmospheric Fine Particulate Matter: Beyond the Priority Pollutant List

    Creator:
    Kramer, Amber L.
    Abstract:
    Atmospheric fine particulate matter (PM2.5) has been linked to the death of 7 million people per year around the planet. The organic portion of PM2.5 is responsible for increases in oxidative stress, inflammation, mutation and carcinogenesis. Anthropogenic activity releases more organic material into the atmosphere, and has increased the amount...
    Resource Type:
    Dissertation
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    , Claudia Meier, Mark Dolan, Alla Zelenyuk, and Stephen Giovannoni for their patience and guidance through