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Filtering by: Creator Richman, James Academic Affiliation Chemistry

Cyclization of olefinic β-ketoesters. An approach to the synthesis of aplysistatin

Creator:

Skeean, Richard William

Resource Type:

Dissertation

Full Text:

. An Approach to the Synthesis of Aplysistatin Abstract Approved: Redacted for privacy 7/ Dr. James D
Synthesis of marine natural products. part I, Cryptophycins-1, -3, -4, -24, and -29, part II, Polycavernoside A

Creator:

Robarge, Lonnie A.

Resource Type:

Dissertation

Full Text:

A. Abstract approved:, James D. White Part 1: A convergent synthesis of cryptophycins has been
Cis-2,5-diaminobicyclo[2.2.2]octane : a novel C₂-symmetric scaffold for asymmetric catalysis

Creator:

Shaw, Subrata

Abstract:

This thesis describes the development of a new enantioselective synthetic method employing chiral cis-2,5-diaminobicyclo[2.2.2]octane-based organometallic catalysts. The significance of this new method to organic synthesis is illustrated with preparation of enantioenriched products that are transformed to important pharmaceutical agents. Chapter 1 provides a brief historical overview of asymmetric catalysis, especially...

Resource Type:

Dissertation

Full Text:

[2.2.2]octane: A Novel C2-Symmetric Scaffold for Asymmetric Catalysis Abstract approved: James D
New Treatments for HIV and Cancer: Uncovering Bioactive Compounds from Small Molecule Sources

Creator:

Overacker, Ross D.

Abstract:

Small molecule drugs have been instrumental in our fight against diseases, beginning when some of the earliest ancient cultures used plant remedies to treat illnesses. More recently, the skill of isolating and characterizing the active ingredients within bioactive plants and microbial extracts has led to the isolation and design of...

Resource Type:

Dissertation

Full Text:

library screening and the determination of viral inhibition values (IC50). Dr. James Strother analyzed