Index Catalog // ScholarsArchive@OSU

Creator:: Kim, Dojung
Abstract:: This dissertation describes studies of isoprenoid biosynthesis in the phytoflagellate Euglena gracilis. Elucidation of a novel isoprerioid pathway, the 2-Cmethyl-D-erythritol-4-phosphate (MEP) pathway, in addition to the generally known mevalonate (MVA) pathway, led to extensive exploration of the distribution of both pathways in a variety of organisms. To date, photosynthetic eukaryotes...
Resource Type:: Dissertation
Full Text:: , the 2-C- methyl-D-erythritol-4-phosphate (MEP) pathway, in addition to the generally known

Creator:: Grochowski, Laura L.
Abstract:: Molecular genetic and enzymological techniques have been employed to study secondary metabolite biosynthesis. These investigations have focused on two projects: the cloning and heterologous expression of biosynthetic gene clusters from unculturable marine organisms and the characterization of individual enzymes involved in the biosynthesis of the antifungal agent blasticidin S. The...
Resource Type:: Dissertation
Full Text:: -D- tryptophanyl-D--tyrosine) with a 12-carbon tetraketide that appears to be propionate- derived

Creator:: Bajaj, Gaurav
Abstract:: EF-hand proteins are a conserved family of proteins that are modulated by divalent cations and regulate diverse cellular activities. In the present study we characterized the molecular determinants of myosin regulatory light chain (RLC) interaction with several subunits of the N-methyl-D-aspartate (NMDA)-type glutamate receptor. Myosin RLC is an EF-hand protein...
Resource Type:: Dissertation
Full Text:: regulatory light chain (RLC) interaction with several subunits of the N-methyl-D-aspartate (NMDA)- type

Creator:: Li, Shan
Abstract:: Mammalian skin is the largest organ of the body and serves as a barrier to protect the body against chemical, mechanical and pathogenic insults as well as water loss. The epidermis is formed from the primitive ectoderm into a multilayered stratified epithelium, consisting of basal, spinous, granular and outermost cornified...
Resource Type:: Dissertation
Full Text:: , Dr. Theresa Filtz, Dr. Barbara Taylor, Dr. David William) for their support, encouragement and

Creator:: Taur, Jan-Shiang
Abstract:: The goal of this dissertation is to investigate the interaction between cimetidine and dietary flavonoids using the Caco-2 cell transport model. It has been shown that flavonoids can change the bioavailability of pharmaceuticals, either by inhibiting metabolizing enzymes or inhibiting the drug efflux transporters. However, the effect of dietary flavonoids...
Resource Type:: Dissertation
Full Text:: radiation [33]. The flavonoids isolated from cudweed Gnaphalium affme D. Don have been shown insect

Creator:: Al-Ghazawi, Mutasin
Resource Type:: Dissertation
Full Text:: )). Thirty years later William Beal of Ohio University designed the first free-piston engine; an engine that

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