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Filtering by: Academic Affiliation College of Pharmacy Creator Campbell, Adam L.

Regulation of Motility of Myogenic Cells in Filling Limb Muscle Anlagen by Pitx2

Creator:

Campbell, Adam L., Shih, Hung-Ping, Xu, Jun, Gross, Michael K., and Kioussi, Chrissa

Abstract:

Cells of the ventrolateral dermomyotome delaminate and migrate into the limb buds where they give rise to all muscles of the limbs. The migratory cells proliferate and form myoblasts, which withdraw from the cell cycle to become terminally differentiated myocytes. The myogenic lineage colonizes pre-patterned regions to form muscle anlagen...

Resource Type:

Article
The role of the homeodomain transcription factor Pitx2 in regulating skeletal muscle precursor migration and higher order muscle assembly

Creator:

Campbell, Adam L.

Abstract:

Cells of the ventrolateral dermomyotome delaminate and migrate into the limb buds where they give rise to all muscles of the limbs. The migratory cells proliferate and form myoblasts, which withdraw from the cell cycle to become terminally differentiated myocytes. The regulatory mechanisms that control the later steps of this...

Resource Type:

Dissertation