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Filtering by: Committee Member Gombart, Adrian Remove constraint Committee Member: Gombart, Adrian Academic Affiliation College of Pharmacy Remove constraint Academic Affiliation: College of Pharmacy Degree Level Master's Remove constraint Degree Level: Master's

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  • The effect of ascorbate on enzymatic nitroglycerin bioactivation as measured by direct LC-MS/MS determination of nitrite

    Creator:
    Hardardt, Elizabeth Ann
    Abstract:
    This work sought to characterize a link between Vitamin C and nitroglycerin at the level of enzymatic bioactivation. Before we could proceed, we needed to develop a method that sensitively and selectively identified the product of bioactivation, nitrite. We successfully adapted traditional diaminonaphthalene derivatization with the use of stable isotope...
    Resource Type:
    Masters Thesis
    Full Text:
    ” Rochefort, Phil Proteau and Adrian “Fritz” Gombart, and all the researchers who developed the use of

  • Regulation of BCL11B by post-translational modifications

    Creator:
    Liu, Xiao
    Abstract:
    Bcl11b (B-cell lymphoma/leukemia 11b), also known as Ctip2 (Chicken ovalbumin upstream promoter transcription factor (COUP-TF)-interacting protein 2), is a C2H2 zinc finger transcriptional regulatory protein, which is an essential protein for post-natal life in the mouse and plays crucial roles in the development, and presumably function, of several organ systems,...
    Resource Type:
    Masters Thesis
    Full Text:
    . Filtz, Dr. Taifo Mahmud, and Dr. Adrian F. Gombart for serving on my committee and for their advice