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Filtering by: Committee Member Gombart, Adrian Academic Affiliation College of Pharmacy Degree Name Doctor of Philosophy (Ph.D.)

A Nanoparticle Mediated Gene Silencing Approach for the Treatment of Metastatic Ovarian Cancer

Creator:

Schumann, Canan B.

Abstract:

Ovarian cancer, “the silent killer,” is one of the deadliest gynecological diseases due to delayed diagnosis, leading to a heavily disseminated and aggressive metastatic cancer. Therapeutic options are limited at stages III-IV of ovarian cancer, in which debulking surgery and cytotoxic chemotherapy remain the mainstays of intervention. However, these therapeutic...

Resource Type:

Dissertation
Bioactive Microbial Natural Products from Unique Indonesian Black Water Ecosystems

Creator:

Sheng, Yan

Abstract:

The discovery of new antibiotics reached its peak during the golden era of antibiotics in the mid 20th century and continued to thrive until the 1980s. However, after more than 50 years of fruitful exploration and exploitation of microbial natural products the discovery rate of new antibiotics has dropped drastically...

Resource Type:

Dissertation

Full Text:

Proteau, Dr. Jane Ishmael and Dr. Adrian Gombart for their generous time, support, advice and