Index Catalog // ScholarsArchive@OSU

Studies on the ecological functions of the antidiabetic drugs acarbose

Creator:: Tanoeyadi, Samuel
Abstract:: Natural products (a.k.a. secondary metabolites) are produced by living organisms that are not essential for their growth, development, or reproduction, but may play a role in their survival or adaptability in nature. Many secondary metabolites isolated from plants and microbes have found use as molecular probes, drug leads, or medicine...
Resource Type:: Masters Thesis

Metabolomic Profiling of Natural Products from Two Tolypocladium Fungal Species as Part of An Evolutionary Genomics Study

Creator:: Dickey, Bailey J.
Abstract:: This thesis describes an investigation of the natural products chemistry of two fungal species of the genus Tolypocladium. Natural products are small organic molecules that are considered non-essential for cell growth and reproduction, and thus part of secondary metabolism. Chemical profiling of these secondary metabolites using a combination of high-performance...
Resource Type:: Masters Thesis

Inactivation Strategy for Clostridium perfringens Spores Adhered onto Stainless Steel Surfaces

Creator:: Alzubeidi, Yasmeen S.
Abstract:: Clostridium perfringens is a spore-forming pathogenic bacterium that causes a variety of diseases in human and animals. C. perfringens type A isolates produce enterotoxin (CPE) causing food poisoning (FP) and non-food-borne (NFB) gastrointestinal (GI) diseases including antibiotic-associated diarrhea and sporadic diarrhea. C. perfringens type A food poisoning currently ranks as...
Resource Type:: Masters Thesis

The effect of ascorbate on enzymatic nitroglycerin bioactivation as measured by direct LC-MS/MS determination of nitrite

Creator:: Hardardt, Elizabeth Ann
Abstract:: This work sought to characterize a link between Vitamin C and nitroglycerin at the level of enzymatic bioactivation. Before we could proceed, we needed to develop a method that sensitively and selectively identified the product of bioactivation, nitrite. We successfully adapted traditional diaminonaphthalene derivatization with the use of stable isotope...
Resource Type:: Masters Thesis

Elimination of 11-nor-delta-9-tetrahydrocannabinol-9-carboxylic acid when normalized to urinary creatinine

Creator:: Beardsley, Grant D.
Resource Type:: Masters Thesis

The effect of cold-stress on alpha₂ modulation of transmitter release and transmitter uptake in the rat caudal artery

Creator:: Rawson, Cathleen L.
Abstract:: The level of postganglionic sympathetic nerve activity is important in determining the tone of vascular smooth muscle, and subsequent maintenance of normal blood pressure. It is generally agreed that receptors located on postganglionic nerve terminals (pre-junctional alpha₂ receptors) are important in the modulation of neurotransmitter (norepinephrine) release from these nerves....
Resource Type:: Masters Thesis

The absolute bioavailability of dyphylline tablets in human subjects

Creator:: Huston, Thomas K.
Abstract:: Dyphylline has been shown to be rapidly and completely absorbed from oral tablets in an absolute bioavailability study. In a pilot study two healthy male subjects received 1000 mg of dyphylline via intravenous infuson at a rate of 50 mg/min (1.0 ml/min) for 20 minutes. Plasma samples were collected for...
Resource Type:: Masters Thesis

The effects of L-ascorbic acid, thiamine HCl, or L-cysteine on ethanol and acetaldehyde blood levels and disposition

Creator:: Acholonu, Wilfred W.
Abstract:: The effects of L-ascorbic acid, thiamine HC1, or L-cysteine on acetaldehyde blood levels and disposition were investigated in acetaldehyde- treated rats. Rats were treated with ascorbic acid (2 mmoles/kg), thiamine (0.24 mmole/kg), or cysteine (2 mmoles/kg) one hour before the administration of acetaldehyde (6 mmoles/kg). The results show that each...
Resource Type:: Masters Thesis

Antimicrobial vaginal dosage forms employing Dimethyl Fumarate or propionic acid

Creator:: Sahajwalla, Chandrahas G.
Abstract:: Propionic acid, live Propionibacterium shermanii, and Dimethyl Fumarate (DMF) were tested for their stimulatory or inhibitory efects on yeast, bacteria, and molds. The amount of propionic acid required for inhibition of molds was strain specific and equal to or less than that required for inhibition of the yeasts. Live P....
Resource Type:: Masters Thesis

Pharmacokinetics of theophylline and it's N-7 derivatives in rabbits

Creator:: Tavipatana, Wattanaporn
Abstract:: Pharmacokinetics of theophylline and N-7 substituted theophylline in rabbits when administered alone and in various combinations were investigated. This thesis has four chapters dealing with etophylline and theophylline; proxyphylline and theophylline; dyphylline and theophylline; and etophylline, proxyphylline and dyphylline pharmacokinetics when administered concomitantly. All chapters are interrelated. Each chapter has...
Resource Type:: Masters Thesis

ScholarsArchive@OSU

Studies on the ecological functions of the antidiabetic drugs acarbose

Metabolomic Profiling of Natural Products from Two Tolypocladium Fungal Species as Part of An Evolutionary Genomics Study

Inactivation Strategy for Clostridium perfringens Spores Adhered onto Stainless Steel Surfaces

The effect of ascorbate on enzymatic nitroglycerin bioactivation as measured by direct LC-MS/MS determination of nitrite

Elimination of 11-nor-delta-9-tetrahydrocannabinol-9-carboxylic acid when normalized to urinary creatinine

The effect of cold-stress on alpha₂ modulation of transmitter release and transmitter uptake in the rat caudal artery

The absolute bioavailability of dyphylline tablets in human subjects

The effects of L-ascorbic acid, thiamine HCl, or L-cysteine on ethanol and acetaldehyde blood levels and disposition

Antimicrobial vaginal dosage forms employing Dimethyl Fumarate or propionic acid

Pharmacokinetics of theophylline and it's N-7 derivatives in rabbits

Limit your search

Academic Affiliation

Advisor

Commencement Year

Committee Member

Creator

Date

Decade

Degree Field

Degree Level

Degree Name

File Format

Language

License

Non-Academic Affiliation

Peer Reviewed

Resource Type

Rights Statement

Subject

Search Constraints

Search Results

Limit your search