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Filtering by: Creator Shannon, Ceili T. Academic Affiliation College of Pharmacy License Attribution 3.0 United States

Regulation of Motility of Myogenic Cells in Filling Limb Muscle Anlagen by Pitx2

Creator:

Campbell, Adam L., Shih, Hung-Ping, Xu, Jun, Gross, Michael K., and Kioussi, Chrissa

Abstract:

Cells of the ventrolateral dermomyotome delaminate and migrate into the limb buds where they give rise to all muscles of the limbs. The migratory cells proliferate and form myoblasts, which withdraw from the cell cycle to become terminally differentiated myocytes. The myogenic lineage colonizes pre-patterned regions to form muscle anlagen...

Resource Type:

Article

Full Text:

of cyclin-dependent kinases [25]. Alternatively, Pitx2 represses T-box genes by recruiting corepres