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Filtering by: Creator Navara, James Louis Remove constraint Creator: Navara, James Louis Academic Affiliation College of Pharmacy Remove constraint Academic Affiliation: College of Pharmacy Non-Academic Affiliation Oregon State University. Graduate School Remove constraint Non-Academic Affiliation: Oregon State University. Graduate School

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Pharmacokinetics of theophylline and it's N-7 derivatives in rabbits

Creator:

Tavipatana, Wattanaporn

Abstract:

Pharmacokinetics of theophylline and N-7 substituted theophylline in rabbits when administered alone and in various combinations were investigated. This thesis has four chapters dealing with etophylline and theophylline; proxyphylline and theophylline; dyphylline and theophylline; and etophylline, proxyphylline and dyphylline pharmacokinetics when administered concomitantly. All chapters are interrelated. Each chapter has...

Resource Type:

Masters Thesis
Product formulations and in vitro-in vivo evaluation of 1) topical insect repellent formualtions against mosquitoes; 2) oral sustained release formulations of cefaclor and pentoxifylline in adults

Creator:

Chou, Joyce Tian-wei

Resource Type:

Dissertation

Full Text:

materialized. The enthusiasm and optimism of my advisor, Dr. James Ayres, who makes this research an
Development and in vivo testing of novel hydrochlorothiazide gastric retention formulations in healthy volunteers and stage I hypertensive patients

Creator:

Farid, Samar Farghali

Abstract:

This thesis describes in vitro and in vivo evaluation of a gastric retention formulation (GRF) developed at Oregon State University. The formulation was prepared from xanthan gum and locust bean gum as gelling agents and other formulation ingredients were added, then it was originally vacuum oven dried. The effect of...

Resource Type:

Dissertation

Full Text:

Hypertensive Patients. Abstract Approved: James W This thesis describes in vitro and in vivo evaluation of a
Evaluation of gastrointestinal transit time and novel oral acetaminophen product formulation

Creator:

Hossain, Mohammad

Abstract:

Gastrointestinal (GI) transit data were collected using pigs as animal models. Density and size effects of non-disintegrating dosage forms on GI transit were investigated. Total GI transit times range from 2 to 33 days for 22 administrations of these nondisintegrating dosage forms. Pigs are found to not be an appropriate...

Resource Type:

Dissertation

Full Text:

Novel Oral Acetaminophen Product Formulation. Abstract approved: ,Redacted for Privacy James W. Ayres
Bioadhesive polymers in drug product formulations

Creator:

Tavipatana, Wattanaporn

Abstract:

Gastric retention time of single unit dosage forms in swine was found to be much longer than in humans. It was concluded that swine are not a good animal model to study GI transit time of nonerodable or slowly eroded dosage forms. Noneradable and slowly eroded dosage forms used to...

Resource Type:

Dissertation

Full Text:

approved: _Redacted for Privacy ((/ James W. Ayres, Ph /. / Gastric retention time of single unit dosage
Pharmacokinetics and pharmacodynamics of: 1) Oral sustained release acetaminophen suspension in children; 2) Potassium chloride in adults

Creator:

Kalns, John Eric

Resource Type:

Dissertation

Full Text:

., St. Louis, MO.) dissolved in 700 ml 95% ethanol USP. Polyvinylpyrrolidinone (2% w/w), MW 40,000 and
Development and evaluation of a sustained release amoxicillin dosage form

Creator:

Ge, Yan, 1962-

Resource Type:

Masters Thesis

Full Text:

. James W. Ayres. Who was the instructor of my first class I took in the US. That class gave me the
Pharmacokinetic modeling and simulations of gastrointestinal transit effects on drug pharmacokinetics from enteric-coated pellet formulations and their applications

Creator:

Watanalumlerd, Prapoch

Abstract:

Effects of gastrointestinal transit on plasma concentrations of drugs from enteric-coated pellet formulations were demonstrated using pharmacokinetic models describing plasma concentrations of drugs from various enteric-coated pellet formulations. Gastric emptying time, lag time of emptying, and drug release rate from pellets in the small intestine, along with other pharmacokinetic parameters...

Resource Type:

Dissertation

Full Text:

Formulations 3) Development of Leaky Enteric-Coated Pellets Formulations Abstract James W. Effects of
In vitro and in vivo testing of a gastric retention device : development and evaluation of a new colonic delivery system

Creator:

Ahmed, Iman Saad

Abstract:

This thesis describes evaluation of a gastric retention device (GRD) developed at Oregon State University. The device was originally fabricated from Xanthan gum and Locust bean gum. A modified gastric retention device containing other additives was developed and investigated in this work. The modified device was evaluated in vitro for...

Resource Type:

Dissertation

Full Text:

Professor Dr. James Ayres for giving me the chance to be one of his students. I was inspired by his
The absolute bioavailability of dyphylline tablets in human subjects

Creator:

Huston, Thomas K.

Abstract:

Dyphylline has been shown to be rapidly and completely absorbed from oral tablets in an absolute bioavailability study. In a pilot study two healthy male subjects received 1000 mg of dyphylline via intravenous infuson at a rate of 50 mg/min (1.0 ml/min) for 20 minutes. Plasma samples were collected for...

Resource Type:

Masters Thesis

Full Text:

Abstract approved: Redacted for Privacy 0 James W. Ayres,(PV.D. Dyphylline has been shown to be rapidly

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Academic Affiliation

College of Pharmacy[remove]47

Advisor

Ayres, James W.27
Christensen, J. Mark4
Aldrich, Jane V.2
Christensen, John M.2
Cui, Zhengrong2
more Advisors »

Commencement Year

Commencement Year range begin – Commencement Year range end

Current results range from 1984 to 2013

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Committee Member

Christensen, J. Mark5
Proteau, Rosita4
Lesser, Virginia3
Thomas, David3
Ayres, James W.2
more Committee Members »

Creator

Tavipatana, Wattanaporn2
Ahmed, Iman Saad1
Altaf, Syed Azhar1
Bajaj, Gaurav1
Bani Jaber, Ahmad Kh.1
more Creators »

Date

Date range begin – Date range end

Current results range from 1983 to 2012

View distribution

Decade

2010-20194
2000-200915
1990-199920
1980-19898

Degree Field

Pharmacy47

Degree Level

Doctoral42
Master's5

Degree Name

Doctor of Philosophy (Ph.D.)42
Master of Science (M.S.)5

File Format

application/pdf1

Language

English [eng]47

License

All rights reserved15

Non-Academic Affiliation

Oregon State University. Graduate School[remove]47

Peer Reviewed

No46

Resource Type

Dissertation42
Masters Thesis5

Rights Statement

Copyright Not Evaluated32
In Copyright15

Subject

Drugs -- Controlled release6
Acetaminophen -- Controlled release5
Drug delivery systems5
Drugs -- Coatings4
Acetaminophen -- Bioavailability2
more Subjects »

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