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Filtering by: Academic Affiliation College of Pharmacy Non-Academic Affiliation Oregon State University. Undergraduate Research, Scholarship, and the Arts (URSA)

O-Glycosylation of transcription factor BCL11b: truth or myth?

Creator:

Pendergrass, Elizabeth A.

Abstract:

BCL11B, a gene regulatory transcription factor, is known to be a regulator of T cell development in the immune system, and has been identified as a tumor suppressor for T cell leukemias. Defining the molecular events that regulate the activity of BCL11B will provide potential drug targets that will aid...

Resource Type:

Presentation
Unexpected links reflect the noise in networks

Creator:

Yambartsev, Anatoly, Perlin, Michael A., Kovcehgov, Yevgeniy, Shulzhenko, Natalia, Mine, Karina L., Dong, Xiaoxi, and Morgun, Andrey

Abstract:

Gene regulatory networks are commonly used for modeling biological processes and revealing underlying molecular mechanisms. The reconstruction of gene regulatory networks from observational data is a challenging task, especially considering the large number of players (e.g. genes) involved and the small number of biological replicates available for analysis. Herein, we...

Resource Type:

Article

ScholarsArchive@OSU

O-Glycosylation of transcription factor BCL11b: truth or myth?

Unexpected links reflect the noise in networks

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