Index Catalog // ScholarsArchive@OSU

Evaluation of gastrointestinal transit time and novel oral acetaminophen product formulation

Creator:: Hossain, Mohammad
Abstract:: Gastrointestinal (GI) transit data were collected using pigs as animal models. Density and size effects of non-disintegrating dosage forms on GI transit were investigated. Total GI transit times range from 2 to 33 days for 22 administrations of these nondisintegrating dosage forms. Pigs are found to not be an appropriate...
Resource Type:: Dissertation
Full Text:: Methanold 40.00 mL a,b Mallinckrodt, Inc., St. Louis, MO 63147. bib J.T. Baker Chemical Co., Phillipsburg

Tablet machine instrumentation to study tablet compaction and compression of polymer-coated beads into tablets

Creator:: Altaf, Syed Azhar
Resource Type:: Dissertation
Full Text:: Walter and Augsburger (7) measured punch displacement into the die for the Colton 216 with a LVDT, they

Transdermal Delivery of Atenolol to Cats

Creator:: Mohamed, Sumeia M.
Abstract:: This thesis describes in-vitro and in-vivo evaluation of a transdermal atenolol formulation developed at Oregon State University, College of Pharmacy. The formulation was prepared from carbomer as a gel base with propylene glycol, glycerol, ethanol, polysorbate 80 and dimethyl-isosorbide (DMI) as mixture of penetration enhancing agents. The effect of the...
Resource Type:: Dissertation
Full Text:: ), Propylene glycol and Triethanolamine from J.T. Baker Inc (600 Broad St, Phillipsburg, NJ 08865 USA

Solid phase synthesis of dynorphin analogues as probes of Kappa opioid receptors

Creator:: Story, Sandra Catherine
Resource Type:: Dissertation

Effect of pharmaceuticals and natural products on multidrug resistance mediatedtransport in Caco-2 and MDCKII-MDR1 drug transport models

Creator:: Fan, Ying
Abstract:: This thesis details my investigation of some pharmaceuticals and natural products on the transport of drugs which are substrates of P-glycoprotein (P-gp), such as cyclosporin A (CSA) and digoxin by using Caco-2 and MDCKII-MDR1 drug transport models. Three objectives were performed to address this goal. The first objective was to...
Resource Type:: Dissertation

Bcl11b is at the Nexus of Wnt and MAP Kinase Signaling Pathways in Two Stages of Thymocyte Development

Creator:: Selman, Wisam H.
Abstract:: Leukemogenesis, uncontrolled proliferation of dysfunctional, transformed immature lymphocytes, appears, especially in children, to be associated with abrogation of normal lymphopoiesis, and thymopoiesis in the case of T cell leukemias. Sequence specific transcription factors (SSTFs) are nuclear control switches that respond to cellular signals to alter cell state and cell fate...
Resource Type:: Dissertation
Full Text:: experiments and chapters except where explicitly noted below Chapter 2: Walter K. Vogel, Ph.D., conceived

Effects of Medicinal Herbs on Contraction Rate of Cultured Cardiomyocyte. Possible Mechanisms Involved in the Chronotropic Effects of Hawthorn and Berberine in Neonatal Murine Cardiomyocyte

Creator:: Salehi, Satin
Abstract:: Herbs have been used for many centuries in diverse civilizations for the treatment of heart disease. Only a few natural supplements claim to have direct cardiovascular actions including hawthorn (Crataegus spp.) and berberine derived from the Berberidaceae family. Several different studies indicate important cardiovascular effects of hawthorn and berberine. For...
Resource Type:: Dissertation
Full Text:: beginning. I would like to thank Dr. Walter K. Vogel, Dr. Yong Zhang, Sun Hyung Kwon and Kristi Crofoot

Development of novel oral enteric-coated aquaculture vibrio vaccines

Creator:: Wong, George Kaon
Abstract:: An oral Vibrio vaccine for salmonids was developed. The vaccine was produced by spray coating lyophilized formalin-killed whole cells of Vibrio anguillarum (VA LS 1- 74) onto non-pareil sugar beads. Then methacrylic acrylic acid copolymer (Eudragit L-30D) was applied as an enteric protective coating. Using x-ray radiographic techniques, it was...
Resource Type:: Dissertation

Deciphering the molecular mechanisms of the transcriptional regulation mediated by orphan nuclear receptor COUP-TFI and C2H2 zinc finger protein Ctip2

Creator:: Zhang, Lingjuan
Abstract:: COUP-TFI, an orphan nuclear receptor of the steroid/thyroid hormone receptor superfamily, plays important roles in homeostasis and the CNS development, including differentiation, patterning, axonal projection, cell migration, cortical arealization and the temporal specification of neural stem cells. A number of COUP-interacting proteins have been described previously, and the majority of...
Resource Type:: Dissertation
Full Text:: described in Fig. 3.3 and 3.8. Dr. Theresa Filtz and Dr. Walter Vogel provided valuable suggestions for

Novel formulation : development of oral microparticulate non-viral DNA vaccine delivery system against infectious hematopoetic necrosis virus (IHNV) in Rainbow Trout, statistical design in matrix tablets formulation

Creator:: Tantituvanont, Angkana
Abstract:: This dissertation describes two different projects. The first is the development of an oral DNA vaccine delivery system for fish. A novel oral DNA vaccine delivery system was developed for Rainbow Trout by combining non-viral vectors (polycationic liposomes or polycationic polymer) to facilitate the DNA vaccine's uptake by cell membranes...
Resource Type:: Dissertation

ScholarsArchive@OSU

Evaluation of gastrointestinal transit time and novel oral acetaminophen product formulation

Tablet machine instrumentation to study tablet compaction and compression of polymer-coated beads into tablets

Transdermal Delivery of Atenolol to Cats

Solid phase synthesis of dynorphin analogues as probes of Kappa opioid receptors

Effect of pharmaceuticals and natural products on multidrug resistance mediatedtransport in Caco-2 and MDCKII-MDR1 drug transport models

Bcl11b is at the Nexus of Wnt and MAP Kinase Signaling Pathways in Two Stages of Thymocyte Development

Effects of Medicinal Herbs on Contraction Rate of Cultured Cardiomyocyte. Possible Mechanisms Involved in the Chronotropic Effects of Hawthorn and Berberine in Neonatal Murine Cardiomyocyte

Development of novel oral enteric-coated aquaculture vibrio vaccines

Deciphering the molecular mechanisms of the transcriptional regulation mediated by orphan nuclear receptor COUP-TFI and C2H2 zinc finger protein Ctip2

Novel formulation : development of oral microparticulate non-viral DNA vaccine delivery system against infectious hematopoetic necrosis virus (IHNV) in Rainbow Trout, statistical design in matrix tablets formulation

Limit your search

Academic Affiliation

Advisor

Commencement Year

Committee Member

Creator

Date

Decade

Degree Field

Degree Level

Degree Name

File Format

Language

License

Non-Academic Affiliation

Peer Reviewed

Resource Type

Rights Statement

Subject

Search Constraints

Search Results

Limit your search