Index Catalog // ScholarsArchive@OSU

Product formulations and in vitro-in vivo evaluation of 1) topical insect repellent formualtions against mosquitoes; 2) oral sustained release formulations of cefaclor and pentoxifylline in adults

Creator:: Chou, Joyce Tian-wei
Resource Type:: Dissertation
Full Text:: materialized. The enthusiasm and optimism of my advisor, Dr. James Ayres, who makes this research an

Development and in vivo testing of novel hydrochlorothiazide gastric retention formulations in healthy volunteers and stage I hypertensive patients

Creator:: Farid, Samar Farghali
Abstract:: This thesis describes in vitro and in vivo evaluation of a gastric retention formulation (GRF) developed at Oregon State University. The formulation was prepared from xanthan gum and locust bean gum as gelling agents and other formulation ingredients were added, then it was originally vacuum oven dried. The effect of...
Resource Type:: Dissertation
Full Text:: Hypertensive Patients. Abstract Approved: James W This thesis describes in vitro and in vivo evaluation of a

Evaluation of gastrointestinal transit time and novel oral acetaminophen product formulation

Creator:: Hossain, Mohammad
Abstract:: Gastrointestinal (GI) transit data were collected using pigs as animal models. Density and size effects of non-disintegrating dosage forms on GI transit were investigated. Total GI transit times range from 2 to 33 days for 22 administrations of these nondisintegrating dosage forms. Pigs are found to not be an appropriate...
Resource Type:: Dissertation
Full Text:: Novel Oral Acetaminophen Product Formulation. Abstract approved: ,Redacted for Privacy James W. Ayres

Bioadhesive polymers in drug product formulations

Creator:: Tavipatana, Wattanaporn
Abstract:: Gastric retention time of single unit dosage forms in swine was found to be much longer than in humans. It was concluded that swine are not a good animal model to study GI transit time of nonerodable or slowly eroded dosage forms. Noneradable and slowly eroded dosage forms used to...
Resource Type:: Dissertation
Full Text:: approved: _Redacted for Privacy ((/ James W. Ayres, Ph /. / Gastric retention time of single unit dosage

Pharmacokinetics and pharmacodynamics of: 1) Oral sustained release acetaminophen suspension in children; 2) Potassium chloride in adults

Creator:: Kalns, John Eric
Resource Type:: Dissertation
Full Text:: ., St. Louis, MO.) dissolved in 700 ml 95% ethanol USP. Polyvinylpyrrolidinone (2% w/w), MW 40,000 and

Pharmacokinetic modeling and simulations of gastrointestinal transit effects on drug pharmacokinetics from enteric-coated pellet formulations and their applications

Creator:: Watanalumlerd, Prapoch
Abstract:: Effects of gastrointestinal transit on plasma concentrations of drugs from enteric-coated pellet formulations were demonstrated using pharmacokinetic models describing plasma concentrations of drugs from various enteric-coated pellet formulations. Gastric emptying time, lag time of emptying, and drug release rate from pellets in the small intestine, along with other pharmacokinetic parameters...
Resource Type:: Dissertation
Full Text:: Formulations 3) Development of Leaky Enteric-Coated Pellets Formulations Abstract James W. Effects of

In vitro and in vivo testing of a gastric retention device : development and evaluation of a new colonic delivery system

Creator:: Ahmed, Iman Saad
Abstract:: This thesis describes evaluation of a gastric retention device (GRD) developed at Oregon State University. The device was originally fabricated from Xanthan gum and Locust bean gum. A modified gastric retention device containing other additives was developed and investigated in this work. The modified device was evaluated in vitro for...
Resource Type:: Dissertation
Full Text:: Professor Dr. James Ayres for giving me the chance to be one of his students. I was inspired by his

New product formulations, pharmacokinetics and bioavailability of dyphylline

Creator:: Chang, Shyi-Feu
Abstract:: Product formulation and in vitro dissolution characteristics of sustained-release chewable tablet dosage forms are presented in chapter one of this thesis. In vivo single dose and multiple dose studies of two sustained-release formulations as well as one conventional dyphylline formulation are described in chapter two. The pharmacokinetics of dyphylline following...
Resource Type:: Dissertation

Formulation and in vitro-in vivo evaluation of a new compression-coated tablet of amoxicillin/clavulanate and formulation potential of the antimicrobial peptide nisin

Creator:: Bani Jaber, Ahmad Kh.
Abstract:: This thesis is compromised of two distinct formulation sections, which are described below: New compression-coated tablet formulations were developed for amoxicillin/clavulanate. Amoxicillin in an outer coat was separated from clavulanic acid in a core tablet by inactive ingredients in a middle coat. A chewable compression-coated tablet formulation with 50% stearic...
Resource Type:: Dissertation
Full Text:: Peptide Nisin jAbstract Approved: James W. Ay es of two distinct formulation sections, which are This

Development and in vivo testing of a gastric retention device (GRD) in dogs

Creator:: Kapsi, Shivakumar G.
Abstract:: This thesis describes 1) development of a gastric retention device (GRD) to increase gastric retention time of certain drugs, 2) product formulations of an immediate release itraconazole and controlled-release ketoprofen. GRD was fabricated from crosslinked carbohydrate polymers. Rate and extent of hydration of the film in water and in simulated...
Resource Type:: Dissertation
Full Text:: received from my Prof. James W. Ayres during my graduate studies. I consider myself privileged to have

ScholarsArchive@OSU

Product formulations and in vitro-in vivo evaluation of 1) topical insect repellent formualtions against mosquitoes; 2) oral sustained release formulations of cefaclor and pentoxifylline in adults

Development and in vivo testing of novel hydrochlorothiazide gastric retention formulations in healthy volunteers and stage I hypertensive patients

Evaluation of gastrointestinal transit time and novel oral acetaminophen product formulation

Bioadhesive polymers in drug product formulations

Pharmacokinetics and pharmacodynamics of: 1) Oral sustained release acetaminophen suspension in children; 2) Potassium chloride in adults

Pharmacokinetic modeling and simulations of gastrointestinal transit effects on drug pharmacokinetics from enteric-coated pellet formulations and their applications

In vitro and in vivo testing of a gastric retention device : development and evaluation of a new colonic delivery system

New product formulations, pharmacokinetics and bioavailability of dyphylline

Formulation and in vitro-in vivo evaluation of a new compression-coated tablet of amoxicillin/clavulanate and formulation potential of the antimicrobial peptide nisin

Development and in vivo testing of a gastric retention device (GRD) in dogs

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