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Filtering by: Subject Bacterial diseases -- Vaccination Academic Affiliation College of Pharmacy

Rational vaccine development 1) Design of a Triantigen Nasal Anthrax Vaccine Candidate 2) A Novel Lecithin Based Nanoparticle as a Vaccine Delivery System

Creator:

Sloat, Brian R.

Abstract:

Currently, the only anthrax vaccine licensed for human use in the United States is the Anthrax-vaccine-absorbed (AVA or Biothrax®). AVA suffers from several drawbacks, including a complicated and lengthy dosing schedule that requires six initial injections administered over eighteen months, followed by annual boosters. Therefore, a new generation anthrax vaccine...

Resource Type:

Dissertation

Full Text:

preparation that elicits an immune response against a particular disease. The concept of vaccination was
Characterization and Validation of Neisseria gonorrhoeae Proteins GmhAGC and NGO1985 as Molecular Targets for Development of Novel Anti-gonorrhea Therapeutic Interventions

Creator:

Wierzbicki, Igor H.

Abstract:

The sexually transmitted disease gonorrhea, caused by the Gram-negative bacterium and obligate human pathogen Neisseria gonorrhoeae, remains a significant health and economic burden worldwide. In the absence of a protective vaccine, antimicrobial agents are the only pharmacological intervention for patients with gonorrhea. However, due to the remarkable ability of gonococcus...

Resource Type:

Dissertation

Full Text:

The sexually transmitted disease gonorrhea, caused by the Gram-negative bacterium and obligate human