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Filtering by: Creator Chadwick, Amanda Academic Affiliation College of Pharmacy

Safety of Phytoestrogenic Botanical Dietary Supplements: in vivo and in vitro Evaluation of Botanical-Drug Interactions

Creator:

Chen, Luying

Abstract:

Popular botanical dietary supplements marketed for management of menopausal symptoms, including hops (Humulus lupulus L.), red clover (Trifolium pratense) and licorice (Glycyrrhiza uralensis), were evaluated for their potential to alter CYP-mediated drug metabolism clinically and pre-clinically. Both hops and red clover had been reported to inhibit certain cytochrome P450 (CYP)...

Resource Type:

Dissertation

Full Text:

Tonsing- Carter and Dr. Amanda Lee. I would like to thank Dr. Caitlin Howell from UIC for her sincere
Biologically active metabolites from marine microorganisms : methods to identify drug leads and chemical signals

Creator:

Vining, Oliver B.

Abstract:

Microbial natural products represent a massive repository of unique chemical scaffolds with corresponding diverse biological functions. However, in the past decade the development of natural products into new therapeutics has dwindled, in part due to the challenges posed by high rediscovery rates and low throughput associated with classical bioassay-guided fractionation...

Resource Type:

Dissertation

Full Text:

. Mitchell performed phylogenetic and morphological analysis of cultured strains. Dr. Amanda M. Fenner