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Filtering by: Subject DNA-protein interactions Academic Affiliation College of Pharmacy

Deciphering the molecular mechanisms of the transcriptional regulation mediated by orphan nuclear receptor COUP-TFI and C2H2 zinc finger protein Ctip2

Creator:

Zhang, Lingjuan

Abstract:

COUP-TFI, an orphan nuclear receptor of the steroid/thyroid hormone receptor superfamily, plays important roles in homeostasis and the CNS development, including differentiation, patterning, axonal projection, cell migration, cortical arealization and the temporal specification of neural stem cells. A number of COUP-interacting proteins have been described previously, and the majority of...

Resource Type:

Dissertation

Full Text:

recruitment of the 7 CBP/p300 coactivator complex through direct protein-protein interaction