Index Catalog // ScholarsArchive@OSU

Creator:: Zhang, Jinying
Abstract:: Quinolinate (QUIN) is an endogenous neurotoxic product of the kynurenine pathway of tryptophan metabolism. Quinolinate is a selective agonist of the NMDA family of glutamate receptors and, as such, may play a role in the pathology of a number of major central nervous system (CNS) disorders. These include both chronic...
Resource Type:: Masters Thesis
Full Text:: .) Glutamate induces significant neurotoxicity with an EC, for LDH release of 76.2 (95% C.I.: 46.8-124.2) liM

Creator:: Nosal, Daniel Grzegorz
Abstract:: Superwarfarins are anticoagulant rodenticides that are 100 times more potent and 15 times more persistent than warfarin. They have been used since the 1980s and cause over 10,000 cases of accidental and intentional poisonings per year. Apart from inducing uncontrollable bleeding, by inhibiting the vitamin K cycle, superwarfarins can disrupt...
Resource Type:: Dissertation

Creator:: Leelasvatanakij, Leena
Resource Type:: Dissertation
Full Text:: metalloendopeptidase EC 3.4.24.11 (enkephalinase) or angiotensin converting enzyme (Fig 2.2) [Leslie et al., 1982

Creator:: Li, Shan
Abstract:: Mammalian skin is the largest organ of the body and serves as a barrier to protect the body against chemical, mechanical and pathogenic insults as well as water loss. The epidermis is formed from the primitive ectoderm into a multilayered stratified epithelium, consisting of basal, spinous, granular and outermost cornified...
Resource Type:: Dissertation

Creator:: Le, Uyen Minh
Abstract:: Cancer is one of the leading causes of death in the U.S., and new approaches to control cancer are constantly sought. This dissertation is comprised of two parts: (i) improving the uptake and retention of gadolinium in tumors for potential gadoliniumneutron capture therapy (Gd-NCT) and (ii) integration of gemcitabine or...
Resource Type:: Dissertation

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