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Creator:: Sakoulas, George, Nonejuie, Poochit, Kullar, Ravina, Pogliano, Joseph, Rybak, Michael J., and Nizet, Victor
Abstract:: Five cases of bacterial meningitis treated with ceftaroline (4 Streptococcus pneumoniae and 1 Staphylococcus aureus) are summarized here. The pharmacodynamics of human cathelicidin LL-37 and ceftaroline were evaluated against S. pneumoniae. Patients who received ceftaroline 600 mg every 8 h (q8h) (1 S. aureus and 3 S. pneumoniae) were successfully...
Resource Type:: Article
Full Text:: Meningitis with Reference to Human Cathelicidin LL-37 George Sakoulas,a Poochit Nonejuie,b Ravina Kullar,c

Creator:: Levine, Pamela J., Elman, Miriam R., Kullar, Ravina, Townes, John M., Bearden, David T., Vilches-Tran, Rowena, McClellan, Ian, and McGregor, Jessina C.
Abstract:: Background: Epidemiologic studies of skin and soft tissue infections (SSTIs) depend upon accurate case identification. Our objective was to evaluate the positive predictive value (PPV) of electronic medical record data for identification of SSTIs in a primary care setting. Methods: A validation study was conducted among primary care outpatients in...
Resource Type:: Article
Full Text:: study Pamela J Levine1, Miriam R Elman1, Ravina Kullar1, John M Townes2, David T Bearden1, Rowena

Creator:: Casapao, Anthony M., Kullar, Ravina, Davis, Susan L., Levine, Donald P., Zhao, Jing J., Potoski, Brian A., Goff, Debra A., Crank, Christopher W., Segreti, John, Sakoulas, George, Cosgrove, Sara E., and Rybak, Michael J.
Abstract:: Enterococci are among the leading pathogens isolated in hospital-acquired infections. Current antimicrobial options for vancomycin- resistant enterococci (VRE) are limited. Prior data suggest that daptomycin at>6 mg/kg of body weight/day may be used to treat enterococcal infections. We retrospectively evaluated the effectiveness and safety of high-dose daptomycin (HD-daptomycin) therapy (>6...
Resource Type:: Article
Full Text:: Enterococcal Infections Anthony M. Casapao,a,b Ravina Kullar,c Susan L. Davis,b,d Donald P. Levine,e,f Jing J

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