Index Catalog // ScholarsArchive@OSU

Role of Transcriptional Factor COUP-TF-interacting Proteins in Skin Permeability Barrier Development, and in Skin Carcinogenesis, and Role of Lipids in Atopic Dermatitis

Creator:: Li, Shan
Abstract:: Mammalian skin is the largest organ of the body and serves as a barrier to protect the body against chemical, mechanical and pathogenic insults as well as water loss. The epidermis is formed from the primitive ectoderm into a multilayered stratified epithelium, consisting of basal, spinous, granular and outermost cornified...
Resource Type:: Dissertation
Full Text:: Shan Li for the degree of Doctor of Philosophy in Pharmacy presented on February 20th, 2017 Title

Draft Genome Sequence of Streptomyces sp. Strain ventii, Isolated from a Microbial Mat near Hydrothermal Vents within the Axial Seamount in the Pacific Ocean, and Resequencing of the Type Strains Streptomyces lonarensis NCL 716 and Streptomyces bohaiensis 11A07

Creator:: Loughran, Rachel M., Mitchell, Edward A., Vining, Oliver B., Gallegos, David A., Deadmond, Monica C., Wasson, Benjamin J., Pfannmuller, Kaysa M., Paddock, Brie E., Koyack, Marc J., Oline, David K., Ushijima, Blake, Saw, Jimmy H., McPhail, Kerry L., and Videau, Patrick
Abstract:: The draft genome of Streptomyces sp. strain ventii, an environmental isolate recovered from deep-sea hydrothermal vents in the Pacific Ocean, is presented along with the resequenced draft genomes of the type strains Streptomyces bohaiensis 11A07 and Streptomyces lonarensis NCL 716.
Resource Type:: Article
Full Text:: /10.1155/2019/ 5283948. 5. Pan H-Q, Cheng J, Zhang D-F, Yu S-Y, Khieu T-N, Son CK, Jiang Z, Hu J-C, Li W-J

Roles of homeodomain transcription factors during organogenesis

Creator:: Xu, Jun
Abstract:: The spatial and temporal patterning of sequence specific transcription factors (SSTFs) contributes to cell type specification and organ formation during embryogenesis. Homeodomain transcription factors are evolutionally conserved among invertebrate and vertebrate animals. They are responsible for body segmentation and organogenesis. Lbx1 and Pitx2 both are homeodomain transcription factors contributing to...
Resource Type:: Dissertation
Full Text:: committed to diverse cellular fates (Cheng et al., 2005, Brohl et al., 2008, Huang et al., 2008). It has

Gene networks during cardiogenesis and skeletal myogenesis

Creator:: Ma, Hsiao-Yen
Abstract:: Organismal development requires a precisely orchestrated transcriptional program to correctly deploy genetic information into the genome. This process requires sophisticated gene regulatory networks at multiple spatial and temporal levels from early embryonic development to adult physiological conditions. Molecular differences that define cell types are set up during the pattern formation...
Resource Type:: Dissertation
Full Text:: (Dodou et al., 2004; Li et al., 2010). Foxh1 is essential for RV formation (von Both et al., 2004

Nonmuscle myosins II-B and Va are components of detergentresistant membrane skeletons derived from mouse forebrain

Creator:: Ishmael, Jane E., Safic, Masa, Amparan, David, Vogel, Walter K., Pham, Tuyen, Marley, Kevin, Filtz, Theresa M., and Maier, Claudia S.
Abstract:: Myosins are actin-based molecular motors that may have specialized trafficking and contractile functions in cytoskeletal compartments that lack microtubules. The postsynaptic excitatory synapse is one such specialization, yet little is known about the spatial organization of myosin motor proteins in the mature brain. We used a proteomics approach to determine...
Resource Type:: Preprint and Article
Full Text:: neurotransmitter glutamate (Cheng et al. 2006; Collins et al. 2006). Myosins are protein complexes comprised of

Regulation of Redox Homeostasis in Skin Cells for the Prevention of UV-Induced Stress and Treatment of Melanoma

Creator:: Carpenter, Evan L.
Abstract:: Melanocytes are dendritic, pigment-producing cells located in the skin and are responsible for its protection against the deleterious effects of solar ultraviolet radiation (UVR), which include DNA damage and elevated reactive oxygen species (ROS). They do so by synthesizing photoprotective melanin pigments and distributing them to adjacent skin cells (e.g.,...
Resource Type:: Dissertation

Pitx2 expression induces cell cycle exit and p21 expression in neural stem cells

Creator:: Heldring, Nina, Joseph, Bertrand, Hermanson, Ola, and Kioussi, Chrissa
Abstract:: Cortical development is a complex process that involves many events including proliferation, cell cycle exit, and differentiation that need to be appropriately synchronized.. Neural stem cells (NSCs) isolated from embryonic cortex are characterized by their ability of self-renewal under continued maintenance of multipotency. The G1 phase of the cell cycle...
Resource Type:: Article
Full Text:: stem cell and progenitor pool size and protects them from exhaustion {Cheng, 2000 #184}. Here we show

Inhalable Lipid Nanoparticles for Messenger RNA Therapeutics

Creator:: Kim, Jeonghwan
Abstract:: Messenger RNA (mRNA) therapy has massive potential to treat various genetic disorders by providing effective proteins to the diseased cells and tissues. Its therapeutic applications include protein replacement, genome editing, and immunotherapy. For successful mRNA treatment, mRNA must be delivered to the cytosol of target cells. One of the leading...
Resource Type:: Dissertation

Investigating Multimodal Therapies with Nanotechnology to Engineer Advanced Chemoradiation Platforms

Creator:: DuRoss, Allison N.
Abstract:: The potential for nanomedicine to reduce toxicity and improve therapeutic response to radiation is vast. Clinically, this potential has thus far only begun to be realized with the recent success of the radioenhancing nanoparticle, NBTXR3 by Nanobiotix. Radioenhancing nanoparticles, however, represent only a small class of nanomaterials that may be...
Resource Type:: Dissertation

Synthesis and biological evaluation of dynorphin a analogues as pharmacological probed of opioid receptors

Creator:: Choi, Heekyung
Resource Type:: Dissertation
Full Text:: lumbosacral spinal cord (Atta li et al., 1982). Further evidence for distinct K-receptor subtypes was

ScholarsArchive@OSU

Role of Transcriptional Factor COUP-TF-interacting Proteins in Skin Permeability Barrier Development, and in Skin Carcinogenesis, and Role of Lipids in Atopic Dermatitis

Draft Genome Sequence of Streptomyces sp. Strain ventii, Isolated from a Microbial Mat near Hydrothermal Vents within the Axial Seamount in the Pacific Ocean, and Resequencing of the Type Strains Streptomyces lonarensis NCL 716 and Streptomyces bohaiensis 11A07

Roles of homeodomain transcription factors during organogenesis

Gene networks during cardiogenesis and skeletal myogenesis

Nonmuscle myosins II-B and Va are components of detergentresistant membrane skeletons derived from mouse forebrain

Regulation of Redox Homeostasis in Skin Cells for the Prevention of UV-Induced Stress and Treatment of Melanoma

Pitx2 expression induces cell cycle exit and p21 expression in neural stem cells

Inhalable Lipid Nanoparticles for Messenger RNA Therapeutics

Investigating Multimodal Therapies with Nanotechnology to Engineer Advanced Chemoradiation Platforms

Synthesis and biological evaluation of dynorphin a analogues as pharmacological probed of opioid receptors

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