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Filtering by: Creator Loh, Woh Ping Academic Affiliation College of Pharmacy

Analysis of nonlinear pharmacokinetic systems and the nonlinear disposition of phenylbutazone in equine (horses)

Creator:

Ma, Lian

Abstract:

The first part of the dissertation is to evaluate the use of proposed and established equations for area under the plasma concentration versus time (AUC) for molecules undergoing nonlinear Michaelis–Menten pharmacokinetic elimination. The effects of varying Michaelis-Menten parameters, rate of drug absorption, or bioavailability on the predictability of drug exposure...

Resource Type:

Dissertation

Full Text:

FDA, Dr. Ying Fan, Dr. Ping Ji and Dr. Yaning Wang for their patient guidance and warm help to make
Comparison of pharmacokinetic data analysis with two competing pharmacokinetic software program

Creator:

Karnpracha, Chanida

Abstract:

Pharmacokinetics (PK) is the study of the transit of drug into, within and removal from the body to reveal how the body acts on a drug when it is taken. There are four major areas in PK: absorption, distribution, metabolism and elimination. Pharmacokinetics research can be separated into two areas:...

Resource Type:

Masters Thesis