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Filtering by: Advisor Morgun, Andrey Academic Affiliation College of Pharmacy

Identification of Cervical Cancer Key Regulators using Network Biology Approach

Creator:

Vyshenska, Dariia

Abstract:

Cervical cancer is the fourth most common cancer in women worldwide with human papillomavirus (HPV) being the main cause of the disease. Currently available treatment methods are limited and emphasize the need for discovery of new therapies that improve patient outcome. Chromosomal amplifications have been identified as a source of...

Resource Type:

Dissertation

Full Text:

. Abstract approved: ______________________________________________________ Andrey Morgun
Unexpected links reflect the noise in networks

Creator:

Yambartsev, Anatoly, Perlin, Michael A., Kovcehgov, Yevgeniy, Shulzhenko, Natalia, Mine, Karina L., Dong, Xiaoxi, and Morgun, Andrey

Abstract:

Gene regulatory networks are commonly used for modeling biological processes and revealing underlying molecular mechanisms. The reconstruction of gene regulatory networks from observational data is a challenging task, especially considering the large number of players (e.g. genes) involved and the small number of biological replicates available for analysis. Herein, we...

Resource Type:

Article

Full Text:

, Xiaoxi Dong2, Andrey Morgun2. AY & AM equally contributed to this work. Correspondence to: anemorgun
Development and implementation of a transkingdom network analysis pipeline to identify drivers of disease

Creator:

Newman, Nolan K.

Abstract:

The gut microbiome has been previously implemented in a number of diseases. Of note is its substantial role in metabolic syndrome, which encapsulates a group of conditions that increase the risk of cardiovascular disease, type 2 diabetes, and stroke. Understanding the causal relationships between the gut microbiome and host processes...

Resource Type:

Dissertation

Full Text:

Andrey Morgun The gut microbiome has been previously implemented in a number of diseases. Of