Index Catalog // ScholarsArchive@OSU

Creator:: Thornburg, Christopher C.
Abstract:: Metagenomics has revealed that the marine microbial biosphere is immensely more diverse than originally considered, and is an almost untapped reservoir for the potential discovery of microbial natural products. Despite numerous advances in culturing, biosynthetic engineering and genomic-based screening efforts to uncover much of this diversity in relatively accessible environments,...
Resource Type:: Dissertation
Full Text:: external committee members, Dr. Martin Schuster and Dr. Daniel Rockey for your time and assistance during

Creator:: Williamson, R. Thomas
Resource Type:: Dissertation
Full Text:: him for giving me the opportunity to meet Dr. Gary B. Martin who continues to be a good friend and

Creator:: Sabry, Omar Mohamed
Abstract:: This thesis is an account of investigation on the natural products deriving from various marine algae and has resulted in the discovery of eleven novel bioactive metabolites. Isolation and characterization of these new molecules were carried out using different chromatographic techniques and by analyses of different spectroscopic data, respectively. Using...
Resource Type:: Dissertation
Full Text:: , T. G.; Fregeau, N. L.; Stroh, J. G.; Kiefer, P. A.; Sun, F.; Li, L. H.; Martin, 0. G. J. Org. Chem

Creator:: Liu, Xiao
Abstract:: Bcl11b (B-cell lymphoma/leukemia 11b), also known as Ctip2 (Chicken ovalbumin upstream promoter transcription factor (COUP-TF)-interacting protein 2), is a C2H2 zinc finger transcriptional regulatory protein, which is an essential protein for post-natal life in the mouse and plays crucial roles in the development, and presumably function, of several organ systems,...
Resource Type:: Masters Thesis
Full Text:: , 2002; Kuppers et al., 2002; Martin-Subero et al., 2002; Martinez- Climent et al., 2003; Satterwhite et

Creator:: Carpenter, Evan L.
Abstract:: Melanocytes are dendritic, pigment-producing cells located in the skin and are responsible for its protection against the deleterious effects of solar ultraviolet radiation (UVR), which include DNA damage and elevated reactive oxygen species (ROS). They do so by synthesizing photoprotective melanin pigments and distributing them to adjacent skin cells (e.g.,...
Resource Type:: Dissertation

Creator:: Vining, Oliver B.
Abstract:: Microbial natural products represent a massive repository of unique chemical scaffolds with corresponding diverse biological functions. However, in the past decade the development of natural products into new therapeutics has dwindled, in part due to the challenges posed by high rediscovery rates and low throughput associated with classical bioassay-guided fractionation...
Resource Type:: Dissertation

Creator:: Nogle, Lisa Marie
Abstract:: This thesis details my investigations of marine cyanobacterial natural products that resulted in the discovery of thirteen new secondary metabolites, the isolation of over fifteen previously reported metabolites and the biosynthetic investigation of two additional cyanobacterial compounds. Two novel lipopeptides were identified from a Lyngbya majuscula and Schizothrix sp. assemblage...
Resource Type:: Dissertation
Full Text:: ) Rinehart, K. L.; Holt, T. 0.; Fregeau, N. L.; Stroh, J. G.; Kiefer, P. A.; Sun, F.; Li, L. H.; Martin, D. G

ScholarsArchive@OSU