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Filtering by: Creator Tzeng, Shin-Cheng Remove constraint Creator: Tzeng, Shin-Cheng Academic Affiliation College of Pharmacy Remove constraint Academic Affiliation: College of Pharmacy

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  • Boosting Intracellular Delivery of mRNA Therapeutics

    Creator:
    Patel, Siddharth D.
    Abstract:
    Intracellular delivery of mRNA holds great potential for vaccine and therapeutic discovery and development. This is realized by the preeminent role mRNA is playing in the record-breaking pace of SARS-CoV-19 vaccine development. Recent advances in chemical modifications of mRNA have enabled high-efficiency gene expression with superior spatiotemporal control while eliminating...
    Resource Type:
    Dissertation

  • Deciphering the Function of New Gonorrhea Vaccine Candidates in Cell Envelope Homeostasis

    Creator:
    Baarda, Benjamin I.
    Abstract:
    Neisseria gonorrhoeae is the sexually transmitted pathogen responsible for millions of cases of gonorrhea worldwide each year. Rapidly-spreading antibiotic resistance is diminishing the ability to effectively treat a disease with significant consequences to female and male reproductive health, as well as to neonatal well-being. A protective vaccine has the potential...
    Resource Type:
    Dissertation