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Filtering by: Creator Xie, Pengfei Academic Affiliation College of Pharmacy

Transcriptional Regulation and Increased Production of Asukamycin in Engineered Streptomyces nodosus subsp. asukaensis Strains

Creator:

Xie, Pengfei, Sheng, Yan, Ito, Takuya, and Mahmud, Taifo

Abstract:

Asukamycin, a member of the manumycin family of antibiotics, exhibits strong antibacterial, antifungal, and anti-neoplastic activities. However, its production in the wild-type strain of Streptomyces nodosus subsp. asukaensis ATCC 29757 is relatively low. Recently, the biosynthetic gene cluster for asukamycin was identified in the producing organism and among the 36...

Resource Type:

Article

Full Text:

Asukamycin in Engineered Streptomyces nodosus subsp. asukaensis Strains Pengfei Xie, Yan Sheng, Takuya