Index Catalog // ScholarsArchive@OSU

Creator:: Phaosiri, Chanokporn
Abstract:: The discovery of the methylerythritol phosphate pathway (the MEP pathway) as an alternate pathway for isoprenoid biosynthesis in some organisms including most bacteria, malarial parasites and plants, but not in animals, has stimulated extensive studies in this area. Research has revealed the potential of finding novel antibacterials, antimalarial drugs, and...
Resource Type:: Dissertation
Full Text:: ethylerythritol triacetate derivative from the enzymatic reaction. C). Co-injection of synthetic and enzymatically

Creator:: Ma, Lian
Abstract:: The first part of the dissertation is to evaluate the use of proposed and established equations for area under the plasma concentration versus time (AUC) for molecules undergoing nonlinear Michaelis–Menten pharmacokinetic elimination. The effects of varying Michaelis-Menten parameters, rate of drug absorption, or bioavailability on the predictability of drug exposure...
Resource Type:: Dissertation
Full Text:: . (ka = 1 hr-1, Vm = 20 mg/hr) ...................................................... 19 Figure 1-4-C

Creator:: Fernandes, Roberta P. M.
Abstract:: In recent years, the methyl erythritol phosphate (MEP) pathway to isoprenoids has been the subject of intensive research. The interest is because isoprenoids have important roles in many cellular processes essential for the survival of several pathogenic organisms, making the inhibition of this pathway an attractive target for the drug...
Resource Type:: Dissertation
Full Text:: mechanisms for the rearrangement of DXP to the 2-C- methylerytbrose 4-phosphate intermediate

Creator:: Tavipatana, Wattanaporn
Abstract:: Pharmacokinetics of theophylline and N-7 substituted theophylline in rabbits when administered alone and in various combinations were investigated. This thesis has four chapters dealing with etophylline and theophylline; proxyphylline and theophylline; dyphylline and theophylline; and etophylline, proxyphylline and dyphylline pharmacokinetics when administered concomitantly. All chapters are interrelated. Each chapter has...
Resource Type:: Masters Thesis
Full Text:: rpm at 4°C for 30 min.15 Plasma was separated and frozen until assayed. Assay 25 pl of plasma was

Creator:: Ali, Seham A.
Abstract:: An in vitro labeling procedure was developed based on optimal conditions of anticoagulant, stannous ion concentration, incubation time, and incubation temperature. This procedure was used to investigate the effects of various agents on Tc-99m RBC labeling yields. These agents were inorganic ions, therapeutic agents, biochemicals, chelating agents, oxidizing agents, an...
Resource Type:: Dissertation
Full Text:: Ferric ammonium citrate x x C-14 Glycine x x x C-11 Carbon monoxide x x P-32 Diisopropyl fluoro

Creator:: Carpenter, Evan L.
Abstract:: Melanocytes are dendritic, pigment-producing cells located in the skin and are responsible for its protection against the deleterious effects of solar ultraviolet radiation (UVR), which include DNA damage and elevated reactive oxygen species (ROS). They do so by synthesizing photoprotective melanin pigments and distributing them to adjacent skin cells (e.g.,...
Resource Type:: Dissertation
Full Text:: (BTB) domain, the BTB and c-terminal kelch (BACK) domain, and six kelch motifs (Figure 1.12.1B

Creator:: Arttamangkul, Seksiri
Resource Type:: Dissertation
Full Text:: APPROVED: Major Professor, representing College of Pharmacy Dean of College of Pharmacy Dean of Gradua c

ScholarsArchive@OSU