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Genetic Susceptible Locus in NOTCH2 Interacts with Arsenic in Drinking Water on Risk of Type 2 Diabetes

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Pan, Wen-Chi, Kile, Molly L., Seow, Wei Jie, Lin, Xihong, Quamruzzaman, Quazi, Rahman, Mahmuder, Mahiuddin, Golam, Mostofa, Golam, Lu, Quan, and Christiani, David C.

Abstract:

Abstract: Background: Chronic exposure to arsenic in drinking water is associated with increased risk of type 2 diabetes mellitus (T2DM) but the underlying molecular mechanism remains unclear. Objectives: This study evaluated the interaction between single nucleotide polymorphisms (SNPs) in genes associated with diabetes and arsenic exposure in drinking water on...

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Genetic Susceptible Locus in NOTCH2 Interacts with Arsenic in Drinking Water on Risk of Type 2 Diabetes

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