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Filtering by: Creator Maier, Claudia Academic Affiliation College of Veterinary Medicine Peer Reviewed Yes

A Multiplex Biomarker Approach for the Diagnosis of Transitional Cell Carcinoma from Canine Urine

Creator:

Bracha, Shay, McNamara, Michael, Hilgart, Ian, Milovancev, Milan, Medlock, Jan, Goodall, Cheri, Wickramasekara, Samanthi, and Maier, Claudia S.

Abstract:

Transitional cell carcinoma (TCC), the most common cancer of the urinary bladder in dogs, is usually diagnosed at an advanced disease stage with limited response to chemotherapy. Commercial screening tests lack specificity and current diagnostic procedures are invasive. A proof of concept pilot project for analyzing the canine urinary proteome...

Resource Type:

Article
Comparative analysis of the surface exposed proteome of two canine osteosarcoma cell lines and normal canine osteoblasts

Creator:

Milovancev, Milan, Hilgart-Martiszus, Ian, McNamara, Michael J., Goodall, Cheri P., Seguin, Bernard, Bracha, Shay, and Wickramasekara, Samanthi I.

Abstract:

Background: Osteosarcoma (OSA) is the most common primary bone tumor of dogs and carries a poor prognosis despite aggressive treatment. An improved understanding of the biology of OSA is critically needed to allow for development of novel diagnostic, prognostic, and therapeutic tools. The surface-exposed proteome (SEP) of a cancerous cell...

Resource Type:

Article

Full Text:

. Acknowledgements The authors would like to acknowledge Prof. Claudia Maier for her critical advice on the project