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Sodium/Proton Antiporter Activity is Essential for Virulence of Yersinia pestis

Creator:: Faulkner, Wyatt J., Ghosh, Amit, Minato, Yusuke, Winogrodzki, Judith, Lind, Erin, Plano, Gregory V., Hinnebusch, Joseph B., Dibrov, Pavel, and Häse, Claudia C.
Abstract:: We found that a strains of Yersinia pestis (KIM5) which lacked the nhaA gene was fully attenuated in a plague model. This gene produces a protein of the sodium-proton antiporter family which expel sodium ions from the bacterial cytoplasm in exchange for hydrogen ions, or protons, from the surrounding environment....
Resource Type:: Poster

Development of monoclonal antibody-based assays for the detection of Vibrio tubiashii zinc-metalloprotease (VtpA)

Creator:: Gharaibeh, Dima N., Biel, Frances M., and Häse, Claudia C.
Abstract:: Vibrio tubiashii has been linked to disease outbreaks in molluscan species, including oysters, geoducks, and clams. In particular, oyster hatcheries in the Pacific Northwest have been plagued by intermittent vibriosis since 2006. Accurate detection of vibrios, including V. tubiashii, is critical to the hatcheries in order to allow for rapid...
Resource Type:: Article
Full Text:: ) Dima N. Gharaibeh, Frances M. Biel, Claudia C. Häse PII: S0167-7012(13)00160-7 DOI: doi: 10.1016

Malonate Inhibits Virulence Gene Expression in Vibrio cholerae

Creator:: Minato, Yusuke, Fassio, Sara R., and Häse, Claudia C.
Abstract:: We previously found that inhibition of the TCA cycle, either through mutations or chemical inhibition, increased toxT transcription in Vibrio cholerae. In this study, we found that the addition of malonate, an inhibitor of succinate dehydrogenase (SDH), decreased toxT transcription in V. cholerae, an observation inconsistent with the previous pattern...
Resource Type:: Article
Full Text:: Vibrio cholerae Yusuke Minato1, Sara R. Fassio2, Claudia C. Häse1,2* 1 Department of Biomedical

Na +/H + Antiport Is Essential for Yersinia pestis Virulence

Creator:: Minato, Yusuke, Ghosh, Amit, Faulkner, Wyatt J., Lind, Erin J., Schesser Bartra, Sara, Plano, Gregory V., Jarrett, Clayton O., Hinnebusch, B. Joseph, Winogrodzki, Judith, Dibrov, Pavel, and Hase, Claudia C.
Abstract:: Na⁺/H⁺ antiporters are ubiquitous membrane proteins that play a central role in the ion homeostasis of cells. In this study, we examined the possible role of Na⁺/H⁺ antiport in Yersinia pestis virulence and found that Y. pestis strains lacking the major Na⁺/H⁺ antiporters, NhaA and NhaB, are completely attenuated in...
Resource Type:: Article
Full Text:: correspondence to Claudia C. Häse, hasec@science.oregonstate.edu. * Present address: Amit Ghosh, Department of

Vet Gazette ; August 19, 2008

Creator:: Oregon State University. College of Veterinary Medicine
Abstract:: Bi-weekly newsletter of the Oregon State University College of Veterinary Medicine.
Resource Type:: Other
Full Text:: August 19, 2008 Calendar CVM faculty teaches in Chile Dr. Claudia Häse, a microbiologist in the

Vet Gazette ; July 20, 2009

Creator:: Oregon State University. College of Veterinary Medicine
Abstract:: Bi-weekly newsletter of the Oregon State University College of Veterinary Medicine.
Resource Type:: Other
Full Text:: study interactions of organisms in shipping fever complex.” • Dr. Claudia Häse has been awarded

Vet Gazette ; May 27, 2008

Creator:: Oregon State University. College of Veterinary Medicine
Abstract:: Bi-weekly newsletter of the Oregon State University College of Veterinary Medicine.
Resource Type:: Other
Full Text:: small animal practice, Wasilla, Alaska Dr. Claudia Hase studies the bacteria killing off shellfish

Vet Gazette ; April 13, 2009

Creator:: Oregon State University. College of Veterinary Medicine
Abstract:: Bi-weekly newsletter of the Oregon State University College of Veterinary Medicine.
Resource Type:: Other
Full Text:: the General Research Fund (GRF) Spring 2009 solicitation: Häse, Claudia (Dept. of Biomedical New

Vet Gazette ; July 7, 2008

Creator:: Oregon State University. College of Veterinary Medicine
Abstract:: Bi-weekly newsletter of the Oregon State University College of Veterinary Medicine.
Resource Type:: Other
Full Text:: . Claudia Hase, $12,500, “Elimination of Vibrio tubiashii Toxins from Seawater Delivered to Oyster

Vet Gazette ; January 8, 2008

Creator:: Oregon State University. College of Veterinary Medicine
Abstract:: Bi-weekly newsletter of the Oregon State University College of Veterinary Medicine.
Resource Type:: Other
Full Text:: Association (SCAVMA), will begin at 6 p.m. in the C&E Auditorium of the LaSells Stewart Center. It is free

ScholarsArchive@OSU

Sodium/Proton Antiporter Activity is Essential for Virulence of Yersinia pestis

Development of monoclonal antibody-based assays for the detection of Vibrio tubiashii zinc-metalloprotease (VtpA)

Malonate Inhibits Virulence Gene Expression in Vibrio cholerae

Na +/H + Antiport Is Essential for Yersinia pestis Virulence

Vet Gazette ; August 19, 2008

Vet Gazette ; July 20, 2009

Vet Gazette ; May 27, 2008

Vet Gazette ; April 13, 2009

Vet Gazette ; July 7, 2008

Vet Gazette ; January 8, 2008

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