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Filtering by: Subject Rhythm Academic Affiliation College of Veterinary Medicine

Loss of rhythmic circadian clock gene expression is associated with decreases in estrogen receptor expression in canine mammary cancer

Creator:

Hughes, Kelly L.

Abstract:

The endogenous circadian clock is an intracellular transcriptional feedback loop timing daily patterns of multiple biological rhythms within a 24-hour period. Disturbance in various rhythms leads to alteration of normal biological processes including cellular proliferation and tumor suppression. Endogenous circadian clock rhythms have been found to be disrupted in breast...

Resource Type:

Masters Thesis

Full Text:

breast cancer. These findings support the increasing evidence that circadian rhythm interference leads