Search Constraints

Start Over
Filtering by: Creator Hinkle, Stephen R. Remove constraint Creator: Hinkle, Stephen R. Academic Affiliation Electrical Engineering and Computer Science Remove constraint Academic Affiliation: Electrical Engineering and Computer Science

Search Results

  • Exploration of regression models for cancer noncoding mutation recurrence

    Creator:
    Xu, Tanjin
    Abstract:
    An important impact of the genome technology revolution will be the elucidation of mechanisms of cancer pathogenesis, leading to improvements in the diagnosis of cancer and the selection of cancer treatment. Integrated with current well-studied massive knowledge and findings about the role of protein-coding mutations in cancer, demystifying the functional...
    Resource Type:
    Masters Thesis
    Full Text:
    for Cancer Noncoding Mutation Recurrence Abstract approved: Stephen A. Ramsey An important impact

  • Variant Annotation

    Creator:
    He, Jun
    Abstract:
    With the development of technologies in genome sequencing and variant detection, a huge number of variants are detected. To further analyze the variants, it requires an efficient tool to annotate the functional effect of variants. This project managed to develop an efficient program to annotate the functional effect of variants...
    Resource Type:
    Capstone Project
    Full Text:
    approved: Stephen Ramsey With the development of technologies in genome sequencing and variant detection

  • Machine Learning for Precision Medicine: Application to Cancer Chemotherapy Response Prediction and Wound Healing Status Assessment

    Creator:
    Wei, Qi
    Abstract:
    Ph.D. candidate Qi Wei's thesis consists of two projects: Chemotherapy Project: a study based on the research paper "Predicting chemotherapy response of various cancer types using a variational auto-encoder approach" submitted to the bioRxiv preprint archive and accepted by the BMC bioinformatics; and Wound Monitor Project: implementing and assessing analytics...
    Resource Type:
    Dissertation
    Full Text:
    Assessment Abstract approved: Stephen A. Ramsey Ph.D. candidate Qi Wei’s thesis consists of two projects

  • Computational Elucidation of the Regulatory SNPs in the Non-Coding Regions of the Human Genome

    Creator:
    Yao, Yao
    Abstract:
    We describe a series of novel computational models, CERENKOV (Computational Elucidation of the REgulatory NonKOding Variome) and its successors CERENKOV2, CERENKOV3, and Convolutional CERENKOV3, for discriminating regulatory single nucleotide polymorphisms (rSNPs) from non-regulatory SNPs within non-coding genetic loci. The CERENKOV models are designed for recognizing rSNPs in the context of...
    Resource Type:
    Dissertation
    Full Text:
    Elucidation of the Regulatory SNPs in the Non-Coding Regions of the Human Genome Abstract approved: Stephen

  • Analytical Methods for Improving Causal Inference

    Creator:
    Sinha, Meghamala
    Abstract:
    Causal inference is an important analytical tool to bridge the gap between prediction and decision-making. However, learning a causal network solely from data is a challenging task. In this work, various techniques have been explored for a better and improved causal network learning from data. Firstly, the problem of learning...
    Resource Type:
    Dissertation
    Full Text:
    : Analytical Methods for Improving Causal Inference Abstract approved: Stephen A. Ramsey Causal inference is

  • Understanding the ultra-wideband channel within a computer chassis

    Creator:
    Redfield, Stephen J.
    Abstract:
    Recent developments in computing technology have generated a demand for more streamlined and effective test systems. By replacing traditional in-chassis wired interconnects with a broadcast wireless system, fault detection and error susceptibility will drastically improve, input/output capabilities will expand, and routing complexity will decrease. Ultra-wideband impulse radio's (UWB-IR) characteristic multipath-immunity...
    Resource Type:
    Masters Thesis
    Full Text:
    AN ABSTRACT OF THE THESIS OF Stephen J. Redfield for the

  • Ultra-low energy digital logic controller design for wireless sensor networks

    Creator:
    Meliza, Stephen W.
    Abstract:
    Low energy design techniques for digital circuits are examined to determine their suitability for use in a digital logic controller for wireless sensor network nodes. Transistor level simulations are used to evaluate the techniques and those demonstrating an energy reduction are used to implement a digital logic controller. The digital...
    Resource Type:
    Masters Thesis
    Full Text:
    1 AN ABSTRACT OF THE THESIS OF Stephen W. Meliza for the degree of

  • Trip Poll: Plan before you ride

    Creator:
    Baisetti, Rama Krishna
    Abstract:
    People like going on trips with friends and tend to plan their trips well in advance to have the best possible experience of a destination and get the most out of the places they visit and/or the activities they plan to partake in. Right now, the Internet provides a wealth...
    Resource Type:
    Capstone Project
    Full Text:
    near the searched location [Stephen, 2015]. Expedia has some good integrations but, as

  • A Formal Foundation for Variational Programming Using the Choice Calculus

    Creator:
    Hubbard, Spencer
    Abstract:
    In this thesis, we present semantic equivalence rules for an extension of the choice calculus and sound operations for an implementation of variational lists. The choice calculus is a calculus for describing variation and the formula choice calculus is an extension with formulas. We prove semantic equivalence rules for the...
    Resource Type:
    Masters Thesis
    Full Text:
    thank all of the members of my graduate committee, including Martin Erwig, Stephen Redfield, and Maggie

  • Don't Fool Me : Detecting Adversarial Examples in Deep Networks

    Creator:
    Li, Xin
    Abstract:
    Deep learning has greatly improved visual recognition in recent years. However, recent research has shown that there exist many adversarial examples that can negatively impact the performance of such an architecture. Different from previous perspectives that focus on improving the classifiers to detect the adversarial examples, this work focuses on...
    Resource Type:
    Masters Thesis
    Full Text:
    enlightened me during my research and my learning process. Second, I would like to thank Dr. Ramsey, Stephen