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Filtering by: Academic Affiliation Environmental and Molecular Toxicology Creator Tilton, Susan C. Creator Tanguay, Robert L.

Bioinformatics resource manager v2.3: an integrated software environment for systems biology with microRNA and cross-species analysis tools

Creator:

Tilton, Susan C., Tal, Tamara L., Scroggins, Sheena M., Franzosa, Jill A., Peterson, Elena S., Tanguay, Robert L., and Waters, Katrina M.

Abstract:

Background: MicroRNAs (miRNAs) are noncoding RNAs that direct post-transcriptional regulation of protein coding genes. Recent studies have shown miRNAs are important for controlling many biological processes, including nervous system development, and are highly conserved across species. Given their importance, computational tools are necessary for analysis, interpretation and integration of high-throughput...

Resource Type:

Article
MicroRNAs control neurobehavioral development and function in zebrafish

Creator:

Tal, Tamara L., Franzosa, Jill A., Tilton, Susan C., Philbrick, Kenneth A., Iwaniec, Urszula T., Turner, Russell T., Waters, Katrina M., and Tanguay, Robert L.

Abstract:

microRNAs (miRNAs) have emerged as regulators of a broad spectrum of neurodevelopmental processes, including brain morphogenesis, neuronal differentiation, and survival. While the role of miRNAs in establishing and maintaining the developing nervous system is widely appreciated, the developmental neurobehavioral role of miRNAs has yet to be defined. Here we show...

Resource Type:

Article