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Filtering by: Contributor Sutherland, Dave Academic Affiliation Environmental and Molecular Toxicology Decade 2000-2009

Investigations into the mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced immune suppression: effects on dendritic cell phenotype and function

Creator:

Vorderstrasse, Beth A.

Abstract:

T cell-dependent immune responses are highly sensitive to suppression by exposure to the environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), yet direct effects of TCDD on T cells have been difficult to demonstrate. Because the activation of naive T cells is initiated by dendritic cells (DC), the studies presented in this dissertation were...

Resource Type:

Dissertation

Full Text:

having "one last breakfast together". It has been my pleasure to work and socialize with Carl, Dave
Chlordecone pretreatment promoted subcellular distribution of scavenger receptor class B type II to murine hepatic microsomes ; mass spectrometry detected hepatic soluble cholesterol binding proteins and comparison of protein iTRAQ ratios using ESI QTOF and MALDI TOF/TOF

Creator:

Scheri, Richard C.

Abstract:

Chlordecone belongs to the class of persistent organochlorine pesticides that are remarkably resistant to environmental degradation. Even though their use was banned in the United States in 1978, these compounds can still be detected in both humans and wildlife throughout the world. Previous work has shown that the pretreatment of...

Resource Type:

Dissertation

Full Text:

. David Williams and Dr. Mark Harmon. Many thanks to Dr. Dave Williams lab and especially to Beth