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Filtering by: Academic Affiliation Environmental and Molecular Toxicology Date issued sim 2009-12-01 Peer Reviewed Yes

Chlordecone Increased Subcellular Distribution of Scavenger Receptor Class B Type II to Murine Hepatic Microsomes without Altering Cytosolic Cholesterol Binding Proteins

Creator:

Scheri, Richard C., Lee, Junga, Barofsky, Douglas F., and Curtis, Lawrence R.

Abstract:

Pretreatment of male C57BL/6 mice with low doses of the persistent organochlorine (OC) pesticide, chlordecone (CD), stimulated biliary excretion of exogenous CH up to 3-fold. Increased biliary excretion occurred without changes in hepatic ATP-binding cassette transporter G8 (ABCG8) of the bile canaliculus or scavenger receptor class B type I (SR-BI)...

Resource Type:

Article