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Filtering by: Creator Meyer, Erik Academic Affiliation Environmental and Molecular Toxicology Degree Field Pharmaceutical Sciences Resource Type Dissertation

Mass spectrometry techniques to assess the metabolism and toxicity of pharmaceutical and dietary nitrates

Creator:

Axton, Elizabeth R.

Abstract:

Nitric oxide (NO) is a signaling molecule that regulates blood pressure and vascular tone. Humans produce NO by endothelial nitric oxide synthase (eNOS), which is impaired in patients with cardiovascular disease leading to increased blood pressure, endothelial dysfunction, and an increased risk of adverse cardiovascular outcomes. Maintaining optimal levels of...

Resource Type:

Dissertation

Full Text:

: Eleonso Cristobal, Jackilyn Toftner, Eunice Lee, Joshua Hay, and Erik McEntire. I acknowledge all past

ScholarsArchive@OSU

Mass spectrometry techniques to assess the metabolism and toxicity of pharmaceutical and dietary nitrates

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