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Filtering by: Creator Rodrigues, Ema G. Academic Affiliation Environmental and Molecular Toxicology Degree Name Doctor of Philosophy (Ph.D.) Subject Helix-loop-helix motifs

Ligand selective regulation of cell growth by the Ah receptor through activation of TGF-beta signaling, Ligand selective regulation of cell growth by the Ah receptor through activation of TGFβ signaling

Creator:

Koch, Daniel C.

Abstract:

The Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor and member of the basic helix-loop-helix Per/ARNT/Sim (bHLH/PAS) family of chemosensors and developmental regulators. As a member of the PAS domain family of transcription factors responsive to exogenous signals, the AhR exerts influence on many processes relating to cellular fate....

Resource Type:

Dissertation

Full Text:

States of America 99(15): 9990-9995. Barretina, J., G. Caponigro, N. Stransky, K. Venkatesan, A. A
Developmental toxicity of polycyclic aromatic hydrocarbons : defining mechanisms with systems-based transcriptional profiling

Creator:

Goodale, Britton C.

Abstract:

Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous in the environment as components of fossil fuels and by-products of combustion. Defining toxicity mechanisms for this large family of multi-ring structures and substituted derivatives is a substantial challenge. Several PAHs, such as benzo(a)pyrene (BaP), are mutagenic, toxic to wildlife, and classified as probable...

Resource Type:

Dissertation

ScholarsArchive@OSU

Ligand selective regulation of cell growth by the Ah receptor through activation of TGF-beta signaling, Ligand selective regulation of cell growth by the Ah receptor through activation of TGFβ signaling

Developmental toxicity of polycyclic aromatic hydrocarbons : defining mechanisms with systems-based transcriptional profiling

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