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The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on T cell activation

Creator:

Shepherd, David M.

Abstract:

The immune system has been identified as a very sensitive target for the toxic effects of 2,3,7,S-tetrachlorodibenzo-p-dioxin (TCDD). Exposure to TCDD has been shown to disrupt the generation of both cell-mediated and humoral T cell-dependent immunity in laboratory animals; however, the mechanism remains unknown. In this dissertation, the hypothesis is...

Resource Type:

Dissertation

Full Text:

The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on T cell
T lymphocyte death as a potential mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced immune suppression

Creator:

Dearstyne, Erica A.

Resource Type:

Dissertation

Full Text:

suppressive effects of TCDD. Exposure to TCDD causes a reduction in T cell numbers and function by unknown