Index Catalog // ScholarsArchive@OSU

Creator:: Pratt, Mary Margaret
Abstract:: Chlorophyllin (CHL), a water-soluble derivative of the green plant pigment, chlorophyll, is an effective antimutagen and anticarcinogen in various model systems when used as a modulator against a class of carcinogens that, in general, have a structure consisting of at least three fused rings. Dibenzo[a,l]pyrene (DBP), an extremely potent environmental...
Resource Type:: Dissertation
Full Text:: Chemoprevention Against Dibenzo[a,/]pyrene-Initiated Multi-organ Carcinogenesis in the Rainbow Trout Model

Creator:: Shilling, Adam D.
Resource Type:: Dissertation
Full Text:: Rainbow Trout by Comparing Liver Slice to Whole Animal Studies AN ABSTRACT OF THE THESIS OF Adam D

Creator:: Lee, Su-Jun
Resource Type:: Dissertation
Full Text:: Cytochrome P450 3A forms in rainbow trout (Oncorhynchus mykiss

Creator:: Ford, Bryan L.
Abstract:: Previous work (Thorgaard, G. H. et al., Aquatic Toxicology 46:121-126, 1999) showed triploid rainbow trout (0. mykiss) given embryonic carcinogen bath exposures had significant reduction of induced tumors relative to diploids. In the present study, trout were made triploid by thermal shock after fertilization. At age of 5 months they...
Resource Type:: Dissertation

Creator:: Rosemond, Marie Victoire M.
Abstract:: Previous studies have shown that rainbow trout exposed to dieldrin via diet for 9 to 12 weeks increased biliary excretion of a subsequent dose of [¹⁴C]dieldrin by 500%. This was not explained by induction of the cytochrome P-450 (CYP) system involved in oxidative metabolism of these compounds. We hypothesized that...
Resource Type:: Masters Thesis
Full Text:: Not Induce Hepatic Microsomal and Cytosolic Epoxide Hydrolase Activities in Rainbow Trout

Creator:: Barnhill, Melanie L.
Abstract:: Feeding rainbow trout 0.3-0.4 mg dieldrinlkg/d for 9-12 weeks stimulated the biliary excretion of a subsequent dose of [¹⁴C]dieldrin by 500% and [³H]7,12- dimethylbenz[a]anthracene (DMBA) by 240%. In vitro work demonstrated that this interaction occurred without induction of the cytochrome P450 system, or other hepatocellular proteins involved in metabolism. The...
Resource Type:: Masters Thesis
Full Text:: Trout (Oncorhyncus mykiss). Abstract approved: Lawrence R. Feeding rainbow trout 0.3-0.4 mg

Creator:: Bravo, Claudia F.
Abstract:: During the past 30 years, numerous studies have focused on the toxicities of polycyclic aromatic hydrocarbons (PAH). Laboratory and field studies have helped elucidate the detrimental effects of these chemicals on growth, reproduction and immune response. Polycyclic aromatic hydrocarbons are in the priority list of chemicals to be studied by...
Resource Type:: Dissertation
Full Text:: examined disease susceptibility of rainbow trout after 50 days of dietary PAH exposure. Rainbow trout

Creator:: Norby, Tyler S.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are significant pollutants in aquatic environments. Many are carcinogenic and lead to DNA fragmentation and adduct formation in marine and freshwater organisms. Previous research demonstrates that rainbow trout (Oncorhynchus mykiss) compensate to long-term PAH dietary exposures and reduce the DNA damage. The aim of this study...
Resource Type:: Masters Thesis
Full Text:: Rainbow Trout (Oncorhynchus mykiss) After Subchronic Exposure to an Environmentally-Relevant Polycyclic

ScholarsArchive@OSU