Index Catalog // ScholarsArchive@OSU

Addressing wastewater epidemiology limitations with the use of dynamic population surrogates, complementary urinalyses and in-situ experiments

Creator:: Brewer, Alex J.
Abstract:: Wastewater epidemiology is an emerging discipline that requires collaborative research involving analytical chemists, drug epidemiologists, and wastewater engineers. Wastewater epidemiology involves the sampling and quantitative analysis of raw wastewaters from communities for illicit drugs and their metabolites. Mass loads (mass per day) and per capita (mg per day per person)...
Resource Type:: Dissertation

Disruptive environmental chemicals and cellular mechanisms that confer resistance to cell death

Creator:: Narayanan, Kannan Badri, Ali, Manaf, Barclay, Barry J., Bisson, William H., Cheng, Qiang, D'Abronzo, Leandro, Dornetshuber-Fleiss, Rita, Gosh, Paramita M., Gonalez-Guzman, Michael J., Lee, Tae-Jin, Leung, Po Sing, Li, Lin, Luanpitpong, Suidjit, Ratoviski, Edward, Rojanasakul, Yon, Romano, Maria Fiammetta, Romano, Simona, Sinha, Kumar Ranjeet, Yedjou, Clement, Al-Mulla, Fahd, Al-Temaimi, Rabeah, Amedei, Amedeo, Brown, Dustin G., Ryan, Elizabeth P., Colacci, Annamaria, Hamid, Roslida A., Mondello, Chiara, Raju, Jayadev, Salem, Hosni K., Woodrick, Jordan, Scovassi, Ivana, Singh, Neetu, Vaccari, Monica, Roy, Rabindra, Forte, Stefano, Memeo, Lorenzo, Kim, Seo Yun, Lowe, Leroy, and Park, Hyun Ho
Abstract:: Cell death is a process of dying within biological cells that are ceasing to function. This process is essential in regulating organism development, tissue homeostasis, and to eliminate cells in the body that are irreparably damaged. In general, dysfunction in normal cellular death is tightly linked to cancer progression. Specifically,...
Resource Type:: Article

Assessing Chemical Dispersants Used During the Deepwater Horizon Oil Spill : Method Innovation and Application

Creator:: Perkins, Matt J.
Abstract:: Large quantities of the chemical oil dispersant Corexit were applied in the Gulf of Mexico (Gulf) in response to the Deepwater Horizon oil spill. Large data gaps regarding the potential transport, persistence and impact of Corexit in the Gulf existed at the time of the emergency response. Analytical methods for...
Resource Type:: Dissertation
Full Text:: Seawater. Environmental Forensics 2015, 16, (4), 333-343. 21. Seidel, M.; Kleindienst, S.; Dittmar, T

Environmental complex mixtures modify benzo[a]pyrene and dibenzo[a,l]pyrene-induced carcinogenesis

Creator:: Courter, Lauren A.
Abstract:: Human exposure to the carcinogenic polycyclic aromatic hydrocarbons (PAHs) benzo[a]pyrene (B[a]P) and dibenzo[a,l]pyrene (DB[a,l]P) is through environmental complex mixtures, such as urban dust particulate matter (UDPM) and diesel exhaust (DE), however the potency of these PAH within a mixture is not established. To determine the effect of these mixtures on...
Resource Type:: Dissertation
Full Text:: (ed.), Environmental Xenobiotics, pp. 333-354. London, UK: Taylor & Francis, 1996. 22 6

Chemopreventative and chemotherapeutic properties of whole cruciferous vegetables and phytochemical components in acute T-cell lymphoblastic leukemia/lymphoma

Creator:: Shorey, Lyndsey E.
Abstract:: Acute lymphoblastic leukemia (ALL) encompasses a spectrum of lymphoid progenitors that have undergone malignant transformation and clonal proliferation at various stages of differentiation. Some cases of ALL have been documented to have prenatal origins and in particular neonatal exposure to various environmental pollutants is associated with increased disease risk, including...
Resource Type:: Dissertation

Indole-3-carbinol and 3,3'-diindolylmethane : relative potency as modulators of drug metabolism and carcinogenesis

Creator:: Katchamart, Sirinmas
Abstract:: Indole-3-carbinol (I3C), the most abundant metabolite of glucobrassicins, is found in cruciferous vegetables such as broccoli, Brussels sprouts, cabbage and cauliflower. I3C has been shown to have anticarcinogenic activity against many chemical carcinogens in multiple target organs in animal models. However, the anticarcinogenic activity of I3C is considered indirect since...
Resource Type:: Dissertation
Full Text:: pH levels is myrosinase (thioglucoside glycohydrolase EC 3:2:3:1). This enzyme is found in the

A proteomic approach to 1,2-dichloroethane bioactivation and reaction with redox-active protein disulfide isomerase

Creator:: Kaetzel, Rhonda Sue
Abstract:: Protein disulfide isomerase (PDI), a member of the thioredoxin superfamily, contains two domains with significant sequence homology to the active sites in thioredoxin. PDI facilitates the folding of nascent proteins in the endoplasmic reticulum (ER), binds hormones and Ca²⁺, catalyzes the glutathione dependent reduction of dehydroascorbate, serves as a major...
Resource Type:: Dissertation
Full Text:: on the redox-active protein disulfide isomerase (EC 5.3.4.1), a member of the thioredoxin

Puget Sound Exhaust Gas Cleaning System (EGCS) Washwater Ecological Risk Assessment

Creator:: Word, Jay, Wang, Dayang (Cindy), McGrath, Joy, and Stubblefield, William
Abstract:: Beginning in 2020, the International Maritime Organization International Convention for the Prevention of Pollution from Ships (MARPOL) required vessels to comply with new sulfur air emission standards in Sulphur Emission Control Areas (Baltic Sea, North Sea, and off the coasts of the US and Canada) by: 1) using 0.1% sulfur...
Resource Type:: Technical Report
Full Text:: Desulfurization EC Effect Concentration ECHA REACH European Chemicals Agency Registration, Evaluation

Disruptive chemicals, senescence and immortality

Creator:: Carnero, Amancio, Blanco-Aparicio, Carmen, Kondoh, Hiroshi, Lleonart, Matilde E., Martinez-Leal, Juan Fernando, Mondello, Chiara, Scovassi, A. Ivana, Bisson, William H., Amedei, Amedeo, Roy, Rabindra, Woodrick, Jordan, Colacci, Annamaria, Vaccari, Monica, Raju, Jayadev, Al-Mulla, Fahd, Al-Temaimi, Rabeah, Salem, Hosni K., Memeo, Lorenzo, Forte, Stefano, Singh, Neetu, Hamid, Roslida A., Ryan, Elizabeth P., Brown, Dustin G., Wise, John P., Sr., Wise, Sandra S., and Yasaei, Hemad
Abstract:: Cell death is a process of dying within biological cells that are ceasing to function. This process is essential in regulating organism development, tissue homeostasis, and to eliminate cells in the body that are irreparably damaged. In general, dysfunction in normal cellular death is tightly linked to cancer progression. Specifically,...
Resource Type:: Article

Developmental toxicity of polycyclic aromatic hydrocarbons : defining mechanisms with systems-based transcriptional profiling

Creator:: Goodale, Britton C.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous in the environment as components of fossil fuels and by-products of combustion. Defining toxicity mechanisms for this large family of multi-ring structures and substituted derivatives is a substantial challenge. Several PAHs, such as benzo(a)pyrene (BaP), are mutagenic, toxic to wildlife, and classified as probable...
Resource Type:: Dissertation

ScholarsArchive@OSU

Addressing wastewater epidemiology limitations with the use of dynamic population surrogates, complementary urinalyses and in-situ experiments

Disruptive environmental chemicals and cellular mechanisms that confer resistance to cell death

Assessing Chemical Dispersants Used During the Deepwater Horizon Oil Spill : Method Innovation and Application

Environmental complex mixtures modify benzo[a]pyrene and dibenzo[a,l]pyrene-induced carcinogenesis

Chemopreventative and chemotherapeutic properties of whole cruciferous vegetables and phytochemical components in acute T-cell lymphoblastic leukemia/lymphoma

Indole-3-carbinol and 3,3'-diindolylmethane : relative potency as modulators of drug metabolism and carcinogenesis

A proteomic approach to 1,2-dichloroethane bioactivation and reaction with redox-active protein disulfide isomerase

Puget Sound Exhaust Gas Cleaning System (EGCS) Washwater Ecological Risk Assessment

Disruptive chemicals, senescence and immortality

Developmental toxicity of polycyclic aromatic hydrocarbons : defining mechanisms with systems-based transcriptional profiling

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