Index Catalog // ScholarsArchive@OSU

Creator:: Siddens, Lisbeth K., Larkin, Andrew, Krueger, Sharon K., Bradfield, Christopher A., Waters, Katrina M., Tilton, Susan C., Pereira, Cliff B., Lohr, Christiane V., Arlt, Volker M., Phillips, David H., Williams, David E., and Baird, William M.
Abstract:: The polycyclic aromatic hydrocarbon (PAH), benzo[a]pyrene (BaP), was compared to dibenzo[def,p]chrysene (DBC) and combinations of three environmental PAH mixtures (coal tar, diesel particulate and cigarette smoke condensate) using a two stage, FVB/N mouse skin tumor model. DBC (4 nmol) was most potent, reaching 100% tumor incidence with a shorter latency...
Resource Type:: Article
Full Text:: adducts resistant to nuclease P1 digestion (Tang et al., 2001). The method provides a summary measure of a

Creator:: Meredith, Ailcea N.
Abstract:: The low risk and sustainable implementation of nanotechnology requires understanding how nanomaterial physicochemical properties influence their toxicity. Major drivers of toxicity need to be avoided while maximizing product efficacy so nanomaterials can be produced to best serve their applications and be of low risk when intentionally or unintentionally released into...
Resource Type:: Masters Thesis
Full Text:: 2 (Albanese, Tang et al. 2012). This can be a benefit for the targeted delivery of therapeutics

Creator:: Slattery, Matthew R.
Abstract:: Nanotechnologies continue to permeate a multitude of industries, with diverse applications ranging from pesticides to fuel additives. The unusual behavior of nanomaterials that drives their innovation also complicates the job of toxicologists tasked with assessing their potential environmental and public health impacts. This dissertation investigates the underlying reasons for uncertainty...
Resource Type:: Dissertation

Creator:: Larkin, Andrew
Abstract:: In 2004 the National Toxicology Program published an article describing their intent to pursue toxicology testing and risk assessment practices solely reliant on high throughput in vitro datasets and in silico modeling for dose-response assessments. Support and contributions form regulatory agencies and a significant portion of the life sciences community...
Resource Type:: Dissertation

ScholarsArchive@OSU