Index Catalog // ScholarsArchive@OSU

Assessing the toxicity of nanoplastics using the primary human bronchial epithelial model

Creator:: Germano, Francesca
Abstract:: Emerging data showing the presence of atmospheric microplastics (MPs) has recently raised awareness surrounding the potential of human nanoplastics (NPs) exposure. Due to factors such as weathering, UV exposure, and other biodegradation processes, plastic pollution in the environment breaks down over time into micro (<5 micrometers) and nanoscale (<1000nm) particles....
Resource Type:: Masters Thesis
Full Text:: such a positive learning experience for us all. To Jamie Pennington and Bryan Harper, no

Assessing Exposures and Simplifying Complex Mixtures of SVOCs for Hazard Characterization using Alternative Model Systems

Creator:: Rivera, Brianna N.
Abstract:: Throughout their lifetime individuals are exposed to complex mixtures of chemicals. The study of chemical mixtures is an internationally recognized research priority, but seemingly complex challenge. To reduce the intricacy of studying mixtures, researchers have identified different prioritization methods based on exposure or the toxicity of chemicals. However, understanding the...
Resource Type:: Dissertation
Full Text:: Brianna N. Rivera for the degree of Doctor of Philosophy in Toxicology presented on June 10, 2022

Investigations of the AhR-induced Treg : transcriptional regulation and suppressive mechanisms

Creator:: Rohlman, Diana
Abstract:: The aryl hydrocarbon receptor (AhR) has recently been described as a novel therapeutic target, given the potent suppression of multiple immune-mediated diseases following activation by the prototypic ligand, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). In the parent-into-F1 graft-versus-host (GVH) model, suppression of the cytotoxic T-lymphocyte (CTL) response is associated with the presence of CD25⁺CTLA-4⁺IL-10⁺Foxp3[superscript...
Resource Type:: Dissertation
Full Text:: tested. The increase in Il22 expression translated to increased IL-22 protein n. Of the 49 genes

Implications for Wildfire Health Recommendations and Remediation Strategies: Source, Fate and Risk of PAHs

Creator:: Ghetu, Christine, C.
Abstract:: (Polycyclic aromatic hydrocarbons) PAHs are widespread in the environment, and are derived from both natural and anthropogenic sources. The physicochemical properties of PAHs along with the wide range of PAH sources leads to their persistence in the environment. Since PAHs are ubiquitous, and have the potential to illicit adverse effects,...
Resource Type:: Dissertation
Full Text:: Wilson, Pete Hoffman, Mike Barton, Jessica Scotten, Jamie Minick, Holly Dixon, Carolyn Poutasse and

TCDD: An Environmental Immunotoxicant Reveals a Novel Pathway of Immunoregulation—A 30-Year Odyssey

Creator:: Kerkvliet, Nancy I.
Abstract:: I was honored to be the keynote speaker at the 30th Annual Society of Toxicologic Pathology Symposium “Toxicologic Pathology and the Immune System.” I had the opportunity to reminisce about events in the 1970s that set the stage for the birth and subsequent growth of the field of immunotoxicology and...
Resource Type:: Article
Full Text:: , research assistant Jamie Pennington and flow cytometry specialist Charles (Sam) Bradford. Last but not

New applications and emerging contaminants : developing silicone passive sampling devices for environmental and novel monitoring applications

Creator:: O'Connell, Steven G.
Abstract:: Passive sampling is a popular technology for environmental monitoring, and silicone is an ideal choice for a variety of passive sampling applications. The silicone work described here encompasses laboratory and field studies that demonstrate the use of this polymer in novel environments, for new applications, and for emerging compounds. Unique...
Resource Type:: Dissertation
Full Text:: , Jamie Pennington and Dr. Nancy Kerkvliet provided in vivo expertise during study design, housing

Indole-3-carbinol in the maternal diet provides chemoprotection for the fetus against transplacental carcinogenesis by dibenzo[a,l]pyrene in the B6 129 mouse model : role of the Aryl Hydrocarbon Receptor

Creator:: Yu, Zhen
Abstract:: Lymphomas and leukemias are the most common cancer in children and young adults and in utero exposure to carcinogens may contribute to the etiology of these cancers. A polycyclic aromatic hydrocarbon (PAH), dibenzo[a,l]pyrene (DBP), was administered to pregnant mice (15 mg/Kg b.w., gavage) on gestation day 17. Significant mortalities in...
Resource Type:: Dissertation
Full Text:: the AHR genotype method. Drs. Roderick H. Dashwood, Nancy I. Kerkvliet, Mark S. Miller, Jamie E

‘Tis a Gift to be Simple : On Passive Sampling and Compatible Techniques for Reducing the Complexity of Environmental Mixtures

Creator:: Bergmann, Alan J.
Abstract:: Assessing the risk from exposure to a chemical mixture in the environment can seem prohibitively challenging. Most components of the mixture are not readily identifiable, chemicals may interact to cause other-than-additive toxicity, and the number of potential combinations of environmental contaminants is enormous. These challenges can make it seem impossible...
Resource Type:: Dissertation
Full Text:: Paulik, Jamie Minick, Holly Dixon, Gary Points, Kevin Hobbie, Matt Perkins, and Ricky Scott deserve

Human Exposure to PAHs in Air, Water, and Crayfish

Creator:: Paulik, L. Blair
Abstract:: There are many links between exposure to environmental pollution and risks to human health. While advances in the fields of toxicology, exposure science, and environmental chemistry have shown light on many of these links, many more research challenges remain. One major challenge is how to accurately characterize the toxicity of...
Resource Type:: Dissertation
Full Text:: , Kevin, Brian, Lane, Alan, Carey, Holly, Jamie, and Pete for all of the training, help, and guidance. I

Toxicogenomic Biomarkers Associated with PAH Carcinogenic Potential in a 3D in Vitro Bronchial Epithelial Model

Creator:: Chang, Yvonne
Abstract:: The environmental health science community recognizes polycyclic aromatic hydrocarbons (PAHs) as a re-emerging class of environmental pollutants due to their persistence and prominence in mixtures of concern. Due to their widespread distribution in the environment, exposure to PAHs often occur as complex chemical mixtures. Exposures are linked to numerous adverse...
Resource Type:: Dissertation
Full Text:: Tilton lab (especially Beth, Zhen, Lauren, Brianna, Celine, Kelley, Andrew, and Jamie), I am thankful

ScholarsArchive@OSU

Assessing the toxicity of nanoplastics using the primary human bronchial epithelial model

Assessing Exposures and Simplifying Complex Mixtures of SVOCs for Hazard Characterization using Alternative Model Systems

Investigations of the AhR-induced Treg : transcriptional regulation and suppressive mechanisms

Implications for Wildfire Health Recommendations and Remediation Strategies: Source, Fate and Risk of PAHs

TCDD: An Environmental Immunotoxicant Reveals a Novel Pathway of Immunoregulation—A 30-Year Odyssey

New applications and emerging contaminants : developing silicone passive sampling devices for environmental and novel monitoring applications

Indole-3-carbinol in the maternal diet provides chemoprotection for the fetus against transplacental carcinogenesis by dibenzo[a,l]pyrene in the B6 129 mouse model : role of the Aryl Hydrocarbon Receptor

‘Tis a Gift to be Simple : On Passive Sampling and Compatible Techniques for Reducing the Complexity of Environmental Mixtures

Human Exposure to PAHs in Air, Water, and Crayfish

Toxicogenomic Biomarkers Associated with PAH Carcinogenic Potential in a 3D in Vitro Bronchial Epithelial Model

Limit your search

Academic Affiliation

Advisor

Commencement Year

Committee Member

Creator

Contributor

Date

Decade

Degree Field

Degree Level

Degree Name

File Format

Language

License

Non-Academic Affiliation

Peer Reviewed

Resource Type

Rights Statement

Subject

Search Constraints

Search Results

Limit your search