Index Catalog // ScholarsArchive@OSU

Creator:: Chibwe, Leah, Geier, Mitra C., Nakamura, Jun, Tanguay, Robert L., Aitken, Michael D., and Simonich, Staci L. Massey
Abstract:: This is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by the American Chemical Society and can be found at: https://doi.org/10.1021/acs.est.5b00499
Resource Type:: Article

Creator:: Corvi, Margaret M., Stanley, Kerri A., Peterson, Tracy S., Kent, Michael L., Feist, Stephen W., La Du, Jane K., Volz, David C., Hosmer, Alan J., and Tanguay, Robert L.
Abstract:: Atrazine (ATZ) is a selective triazine herbicide used primarily for pre-emergent weed control in corn, sorghum and sugar cane production. It is one of the most widely used herbicides in North America. Some research published over the last decade suggests that chronic exposure to environmentally relevant ATZ concentrations can adversely...
Resource Type:: Article
Full Text:: , Tracy S Peterson c,d , Michael L Kent c,d , Stephen W Feist e , Jane K La Du a,d , David C Volz f

Creator:: O’Donnell, Edmond F., Kopparapu, Prasad Rao, Koch, Daniel C., Jang, Hyo Sang, Phillips, Jessica Lynne, Tanguay, Robert L., Kerkvliet, Nancy I., and Kolluri, Siva Kumar
Abstract:: A novel role of the dihydroorotatedehydrogenase (DHODH) inhibitor leflunomide as a potential anti-melanoma therapy was recently reported (Nature 471: 518-22, 2011). We previously reported that leflunomide strongly activates the transcriptional activity of the Aryl Hydrocarbon Receptor (AhR). We therefore tested whether the AhR regulates the anti-proliferative effects of leflunomide in...
Resource Type:: Article
Full Text:: , Daniel C. Koch1,2,5, Hyo Sang Jang1,2,5, Jessica Lynne Phillips1,3,5, Robert L. Tanguay2,3,4,5, Nancy I

Creator:: Tilton, Susan C., Tal, Tamara L., Scroggins, Sheena M., Franzosa, Jill A., Peterson, Elena S., Tanguay, Robert L., and Waters, Katrina M.
Abstract:: Background: MicroRNAs (miRNAs) are noncoding RNAs that direct post-transcriptional regulation of protein coding genes. Recent studies have shown miRNAs are important for controlling many biological processes, including nervous system development, and are highly conserved across species. Given their importance, computational tools are necessary for analysis, interpretation and integration of high-throughput...
Resource Type:: Article

Creator:: Tal, Tamara L., Franzosa, Jill A., Tilton, Susan C., Philbrick, Kenneth A., Iwaniec, Urszula T., Turner, Russell T., Waters, Katrina M., and Tanguay, Robert L.
Abstract:: microRNAs (miRNAs) have emerged as regulators of a broad spectrum of neurodevelopmental processes, including brain morphogenesis, neuronal differentiation, and survival. While the role of miRNAs in establishing and maintaining the developing nervous system is widely appreciated, the developmental neurobehavioral role of miRNAs has yet to be defined. Here we show...
Resource Type:: Article
Full Text:: C. Tilton,‡ Kenneth A. Philbrick,† Urszula T. Iwaniec,† Russell T. Turner,† Katrina M. Waters,‡ and

Creator:: Nahta, Rita, Al-Mulla, Fahd, Al-Temaimi, Rabeah, Amedei, Amedeo, Andrade-Vieira, Rafaela, Bay, Sarah N., Brown, Dustin G., Calaf, Gloria M., Castellino, Robert C., Cohen-Solal, Karine A., Colacci, Annamaria, Cruickshanks, Nichola, Dent, Paul, Di Fiore, Riccardo, Forte, Stefano, Goldberg, Gary S., Hamid, Roslida A., Krishnan, Harini, Laird, Dale W., Lasfar, Ahmed, Marignani, Paola A., Memeo, Lorenzo, Mondello, Chiara, Naus, Christian C., Ponce-Cusi, Richard, Raju, Jayadev, Roy, Debasish, Roy, Rabindra, Ryan, Elizabeth P., Salem, Hosni K., Scovassi, A. Ivana, Singh, Neetu, Vaccari, Monica, Vento, Renza, Vondráček, Jan, Wade, Mark, Woodrick, Jordan, and Bisson, William H.
Abstract:: As part of the Halifax Project, this review brings attention to the potential effects of environmental chemicals on important molecular and cellular regulators of the cancer hallmark of evading growth suppression. Specifically, we review the mechanisms by which cancer cells escape the growth-inhibitory signals of p53, retinoblastoma protein, transforming growth...
Resource Type:: Article
Full Text:: , Gloria M.Calaf6,7, Robert C.Castellino8, Karine A.Cohen-Solal9, Annamaria Colacci10, Nichola

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