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Creator:: Bakalinsky, Alan T. and Watson, Barney T.
Abstract:: Objectives: 1. Isolation or construction of an acid protease-excreting laboratory strain of Saccharomyces cerevisiae. 2. Evaluation of enzyme activity against model protein, protein-tannin, and grape protein substrates. 3. Selection or screening of isolates producing greater enzyme activity with improved specificity. 4. Construction of an acid protease-excreting wine strain of Saccharomyces...
Resource Type:: Technical Report

Creator:: Hadduck, Alex N., Hindagolla, Vihangi, Contreras, Alison E., Li, Qilin, and Bakalinsky, Alan T.
Abstract:: Studies reporting on potentially toxic interactions between aqueous fullerene nanoparticles (nC₆₀) and microorganisms have been contradictory. When known confounding factors were avoided, growth yields of Saccharomyces cerevisiae and Escherichia coli cultured in the presence and absence of independently prepared lots of underivatized nC₆₀ were found not to be significantly different.
Resource Type:: Article

Creator:: Smith, Mark R., Boenzli, Matthew G., Hindagolla, Vihangi, Ding, Jun, Miller, John M., Hutchison, James E., Greenwood, Jeffrey A., Abeliovich, Hagai, and Bakalinsky, Alan T.
Abstract:: Positively-charged gold nanoparticles (0.8-nm core diameter) reduced yeast survival, but not growth, at a concentration of 10 to 100 μg/ml. Among 17 resistant deletion mutants isolated in a genome-wide screen, highly significant enrichment was observed for respiration-deficient mutants lacking genes encoding proteins associated with the mitochondrion.
Resource Type:: Article

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