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Carcinogenicity and acute toxicity of dimethylnitrosamine in rainbow trout (Salmo gairdneri)

Creator:: Grieco, Mary Porter
Abstract:: A dose related carcinogenic response was established for dimethylnitrosamine administered in the diet of rainbow trout (Salmo gairdneri). An equation was derived for the relationship between dose and hepatocellular carcinoma incidence. From a published dose response study using Porton rats as a test animal, a second equation was derived for...
Resource Type:: Masters Thesis
Full Text:: Food Toxicology and Nutrition Laboratory is gratefully acknowledged. Thanks are also due to Gregory

Induction of autoantibodies in MRL/lpr mice exposed to 2% aniline denatured low-erucic acid rapeseed oil, an oil associated with the Spanish Toxic Oil Syndrome

Creator:: Richards, Carolyn L. K.
Abstract:: In 1981, illegal processing of rapeseed oil by a Spanish oil refinery resulted in the mass foodborne illness epidemic known as Toxic Oil Syndrome (TOS). The toxic oil associated with this epidemic was sold in neighborhood markets and by itinerant salesmen as inexpensive olive oil. Ingestion of the toxic oil...
Resource Type:: Masters Thesis

Developmental regulation of flavin-containing monooxygenase (FMO) form 1 and form 2 mRNA in fetal and neonatal rabbit

Creator:: Yueh, Mei-Fei
Abstract:: The mammalian FMO represents a multigene family which oxygenates a large number of xenobiotics. No physiological role has been determined for FMO, although synthesis of disulfide bonds and detoxification of dietary chemicals have been suggested. Five FMO gene subfamilies, each containing a single gene, have been identified. In this study,...
Resource Type:: Masters Thesis
Full Text:: gestation and the letter denotes that these were pooled fetuses from a single maternal rabbit. The number

Synthesis of the 2, 3, 3a, 8a-tetrahydro-2-hydroxy-furo [2, 3-b]benzofuran ring system, an aflatoxin moiety

Creator:: Jones, David James
Abstract:: A new method for the preparation of the 2, 3, 3a,8a-tetrahydro-2-hydroxyfuro[2, 3-b] benzofuran, XXX, ring system has been developed. The synthesis envolved a substitution reaction of phenol, XXIV, with 1-bromo-2, 5-hexadiene, XXV, to give 2, 5-hexadien-l -yl phenyl ether, XXVII. The ether was rearranged via an ortho-Claisen rearrangement to 3-(o-hydroxyphenyl)-l,...
Resource Type:: Masters Thesis
Full Text:: the letter H. The ab- breviations s, d, t, q, and m indicate singlet, doublet, triplet

A study of the DNA excision repair capabilities of rainbow trout (Salmo gairdneri) exposed to dietary cyclopropenoid fatty acids

Creator:: Collier, John Mark
Abstract:: The DNA repair capabilities of rainbow trout (Salmo gairdneri) were studied vising the method of autoradiography. Trout were fed a semi-purified control diet containing 0 ppm, 50 ppm, or 300 ppm cyclopropenoid fatty acids (CPFA) for 6-9 weeks. Liver slices were prepared and exposed in vitro to a control treatment,...
Resource Type:: Masters Thesis
Full Text:: the Food Toxicology and Nutrition Laboratory is appreciated. The times that my caring friend

The significance of glutathione conjugation for aflatoxin B₁ metabolism in rainbow trout and coho salmon

Creator:: Valsta, Liisa M.
Abstract:: In rodent models as well as in fish models there are significant species differences in the susceptibility toward aflatoxin B₁ (AFB₁) carcinogenesis. Mouse is less susceptible toward AFB₁ carcinogenesis than rat. Researchers have come to the conclusion that the lower susceptibility of mice is not a result of less effective...
Resource Type:: Masters Thesis
Full Text:: (Pabst et ah , 1973). This finding led to the renaming of glutathlone transferases by Roman letters

Efficacy of electrolyzed oxidizing water and ozonated water for microbialdecontamination of fresh strawberries (Fragaria x ananassa)

Creator:: Udompijitkul, Pathima
Abstract:: The objectives of this project were to evaluate the efficacies of electrolyzed oxidizing (EO) and ozonated waters as antimicrobial agents for enhancing the microbiological safety of fresh strawberries (Fragaria x ananassa). The influence of sodium chloride (NaCl) concentrations used for preparing EO water was evaluated on their bactericidal activities against...
Resource Type:: Masters Thesis

Factors Affecting the Efficacy of Depuration for Decreasing Vibrio parahaemolyticus Contamination in Pacific Oysters (Crassostrea gigas)

Creator:: Hou, Yishu
Abstract:: Vibrio parahaemolyticus is a foodborne pathogen recognized as the leading cause of acute gastroenteritis associated with consumption of raw and undercooked seafood, particularly raw oysters, with major symptoms of nausea, vomiting, abdominal cramps and diarrhea. It is estimated that 45,000 cases of V. parahaemolyticus infection occur each year in the...
Resource Type:: Masters Thesis

Selective oxidation of biological matrices for subsequent peroxidase and peroxidase-based quantitative analyses

Creator:: Jiang, Shu
Abstract:: Hydrogen peroxide quantification is of broad interest due to the common use of hydrogen peroxide as an oxidizing agent in industrial processing and laboratory research. Hydrogen peroxide assays are also of general importance for biological studies aimed at understanding the role of in situ generated reactive oxygen species. In the...
Resource Type:: Masters Thesis

Some enzyme changes in levers of rainbow trout (Salmo gairdnerii) fed aflatoxin B₁ and sterculic acid

Creator:: Taylor, Stephen Lloyd
Resource Type:: Masters Thesis
Full Text:: artificially spawned and reared at the Food Toxicology and Nutrition Laboratory at this university

ScholarsArchive@OSU

Carcinogenicity and acute toxicity of dimethylnitrosamine in rainbow trout (Salmo gairdneri)

Induction of autoantibodies in MRL/lpr mice exposed to 2% aniline denatured low-erucic acid rapeseed oil, an oil associated with the Spanish Toxic Oil Syndrome

Developmental regulation of flavin-containing monooxygenase (FMO) form 1 and form 2 mRNA in fetal and neonatal rabbit

Synthesis of the 2, 3, 3a, 8a-tetrahydro-2-hydroxy-furo [2, 3-b]benzofuran ring system, an aflatoxin moiety

A study of the DNA excision repair capabilities of rainbow trout (Salmo gairdneri) exposed to dietary cyclopropenoid fatty acids

The significance of glutathione conjugation for aflatoxin B₁ metabolism in rainbow trout and coho salmon

Efficacy of electrolyzed oxidizing water and ozonated water for microbialdecontamination of fresh strawberries (Fragaria x ananassa)

Factors Affecting the Efficacy of Depuration for Decreasing Vibrio parahaemolyticus Contamination in Pacific Oysters (Crassostrea gigas)

Selective oxidation of biological matrices for subsequent peroxidase and peroxidase-based quantitative analyses

Some enzyme changes in levers of rainbow trout (Salmo gairdnerii) fed aflatoxin B₁ and sterculic acid

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